Titanium

Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.

Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

General First Aid:

General First Aid:

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear positive pressure self-contained breathing apparatus (SCBA).

ORDINARY EXTINGUISHERS ARE OFTEN INEFFECTIVE AGAINST TITANIUM FIRES. SUCH FIRES REQUIRE SPECIAL EXTINGUISHERS DESIGNED FOR METAL FIRES. IN AIRTIGHT ENCLOSURES TITANIUM FIRES CAN BE CONTROLLED BY THE USE OF ARGON OR HELIUM. TITANIUM, IN THE ABSENCE OF MOISTURE, BURNS SLOWLY, BUT EVOLVES MUCH HEAT.

DO NOT USE WATER OR CARBON DIOXIDE TO EXTINGUISH.

If material on fire or involved in fire: Cool all affected containers with flooding quantities of water. Use graphite, soda ash, powdered sodium chloride, or suitable dry powder. /Titanium powder, wetted/

If material on fire or involved in fire: Do not use water. Use graphite, soda ash, powdered sodium chloride, or suitable dry powder. /Titanium powder, dry/

Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

ADEQUATE VENTILATION & LUBRICATION SHOULD BE PROVIDED DURING SAWING, GRINDING & POLISHING OF TITANIUM METAL.

SRP: Local exhaust ventilation should be applied wherever there is an incidence of point source emissions or dispersion of regulated contaminants in the work area. Ventilation control of the contaminant as close to its point of generation is both the most economical and safest method to minimize personnel exposure to airborne contaminants.

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Keep material wet. /Titanium powder, dry/

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Keep material wet. /Titanium powder, wetted/

Personnel protection: ... Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. /Titanium powder, dry; titanium powder, wetted/

Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Immediate precautionary measure

Immediate precautionary measure

15 [mg/m3]

170 [mg/m3]

990 [mg/m3]

Excerpt from ERG Guide 135 [Substances - Spontaneously Combustible]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

Excerpt from ERG Guide 170 [Metals (Powders, Dusts, Shavings, Borings, Turnings, or Cuttings, etc.)]:

WORKERS SHOULD ALSO WEAR PERSONAL & RESPIRATORY PROTECTIVE EQUIPMENT WHERE NECESSARY.

· DO NOT USE WATER, CO2 OR FOAM ON MATERIAL ITSELF.

· DO NOT USE WATER, FOAM OR CO2.

... REPORT OF LUNG CHANGES IN ANIMALS EXPOSED FOR 5 MO TO TITANIUM COMBINED WITH CARBON. CHANGES WERE SAID TO RESEMBLE SILICOSIS, LESIONS NOT FOUND IN ANIMALS EXPOSED FOR SEVERAL YR TO DUST OF ... CARBOLOY WHICH CONTAINS TITANIUM CARBON CMPD ... .

/INVESTIGATOR/ ... STUDIED CASE OF CHRONIC LUNG DISEASE IN WORKER EXPOSED TO SEVERAL METALS ... TITANIUM WAS FOUND IN LUNG BIOPSY.

LACK OF TOXICITY ... BY CONTACT WITH SKIN & TISSUES HAS BEEN ... DEMONSTRATED BY ITS USE IN THERAPY OF SKIN DISORDERS & IN SURGICAL APPLIANCES.

Food is considered to be the principal source of titanium exposure for humans. The chemical and biological kinetics and metabolism of titanium are discussed. The only carcinogenic effects of titanium thus far reported have been the development of fibrosarcomas at the injection sites in exposed rats. There is no evidence that titanium is carcinogenic in humans. /It was concluded/ that the current extent of exposure to titanium of the general population does not pose a health risk.

DISKS OF TITANIUM METAL IMPLANTED IN MUSCLE OF DOGS & LEFT IN SITU FOR 7 MO WERE INERT; WOUND HEALED & METAL WAS ENCAPSULATED WITH FIBROUS TISSUE.

INHALATION /OF TITANIUM DUST/ HAS CAUSED ONLY SLIGHT LESIONS OF LUNG ... .

... INERTNESS & LACK OF RESPONSE IN BONE TISSUE HAS ... BEEN SHOWN BY RESULTS OF PLATING & FIXATION OF FRACTURES IN DOGS BY TITANIUM PLATES & SCREWS.

CARCINOGENICITY STUDIES WERE PERFORMED ON 50 RATS USING 6 MONTHLY INTRAMUSCULAR DOSES EACH CONTAINING 6 MG OF TITANIUM METAL POWDER SUSPENDED IN 0.2 ML OF TRIOCTANOIN. INCR RATES OF FIBROSARCOMAS & LYMPHOSARCOMAS WERE OBSERVED IN RATS, WHICH SURVIVED UP TO 820 DAYS COMPARED WITH CONTROLS.

For more Non-Human Toxicity Excerpts (Complete) data for TITANIUM (7 total), please visit the HSDB record page.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poison A and B/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poison A and B/

Titanium

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2010