Monoethylglycinexylidide

MEGX · N-(2,6-DIMETHYLPHENYL)-2-(ETHYLAMINO)ACETAMIDE · Norlidocaine · L-86 · MGEX · Lidocaine-006 · Ethylglycylxylidide · Lidocaine Impurity 9

Identifikatoren & physikalische Daten

CAS No.	7728-40-7
Summenformel	C12H18N2O
Durchschnittliche Molmasse	206,28 g/mol
Monoisotopische Masse	206,1419132 g/mol
SMILES	CCNCC(=O)Nc1c(C)cccc1C
InChIKey	WRMRXPASUROZGT-UHFFFAOYSA-N
PubChem CID	24415
ChEMBL	CHEMBL1028
ChEBI	CHEBI:222828
EC No.	694-788-9
DTXSID	DTXSID60228006

XLogP	1,3
Polarare Oberfläche (TPSA)	41,1
H-Brücken-Donoren	2
H-Brücken-Akzeptoren	2
Frei drehbare Bindungen	4
Schwere Atome	15
Formalladung	0
Komplexität	196
Arzneimittel	Pharmaceuticals -> Metabolite of Lidocaine
Löslichkeit	25.2 [ug/mL] (The mean of the results at pH 7.4)H2O: soluble10mg/mL, clearH2O: 10mg/mL, clear
Schmelzpunkt	242-245°C
Siedepunkt	335.6±30.0℃ (760 Torr)
Dichte	1.047±0.06 g/cm3 (20 ºC 760 Torr)
Flammpunkt	127.8±24.7℃
Lagerbedingungen	2-8°C
pKa (Säurekonstante)	pKa 8.04(H2O,t =25±0.2,I=0.01(NaCl)) (Uncertain)
Aggregatzustand	powder
Farbe	white to beige
Hauptanwendungen	pharmaceutical
InChI	1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)
InChIKey	WRMRXPASUROZGT-UHFFFAOYSA-N
SMILES	CC1=C(NC(CNCC)=O)C(C)=CC=C1

GHS-Einstufung	DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard Classes and Categories	Acute Tox. 3 (100%)
Wassergefährdungsklasse (WGK)	3
UN-Transportnummer	UN 2811 6.1 / PGIII
RTECS-Nr.	AN7740000
R-Sätze (R)	22
Gefahrensymbole	Xn
Sicherheitshinweise (S)	45
Lagerklasse	6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Gefahrenklasse	Acute Tox. 3 Oral

A metabolite of Lidocaine (L397800).