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Trinatriumtrimetaphosphat
STMP · trimetaphosphate · TRISODIUM TRIMETAPHOSPHATE · cyclischestrinatriummetaphosphat · CPD-610 · trisodiummetaphosphate · 2,4,6-trioxido-1,3,5,2 · SODIUM TRIMETAPHOSPHATE
Identifikatoren & physikalische Daten
| CAS No. | 7785-84-4 |
|---|---|
| Summenformel | Na3O9P3 |
| Durchschnittliche Molmasse | 305,89 g/mol |
| Monoisotopische Masse | 305,84482431 g/mol |
| SMILES | O=P1([O-])OP(=O)([O-])OP(=O)([O-])O1.[Na+].[Na+].[Na+] |
| InChIKey | UGTZMIPZNRIWHX-UHFFFAOYSA-K |
| PubChem CID | 24579 |
| ChEMBL | CHEMBL2107557 |
| EC No. | 232-088-3 |
| DTXSID | DTXSID7052789 |
| Lokaler Name | Trinatriumtrimetaphosphat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 148 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 9 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 15 |
| Formalladung | 0 |
| Komplexität | 224 |
| Stoffklassen | Metals -> Phosphates, Metallic Salts |
| Kosmetika | Cosmetic ingredients (Sodium Trimetaphosphate) -> CIR (Cosmetic Ingredient Review)AnticakingChelatingBuffering |
| Decomposition | When heated to decomposition it emits toxic fumes of phosphoxides and sodium oxide. |
| Food Contact Substances | FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR |
| Brechungsindex | COLORLESSINDEX OF REFRACTION: 1.433, 1.442, 1.446 /HEXAHYDRATE/ |
| Physical Description | Dry PowderOther SolidHexahydrate: Efflorescent solid[Merck Index] White odorless powder[MSDSonline] |
| Stability/Shelf Life | LOSES WATER ON STORAGE @ 20 °C /HEXAHYDRATE/ |
| Other Experimental Properties | Loses water on storage at 20 °C, becomes definitely anhydrous at 100 °C. /Hexahydrate/Efflorescent, triclinic-rhombohedral prisms. Melting point 53 °C. Specific gravity 1.786. One gram dissolves in 4.5 ml water. Insol in alc. /Hexahydrate/ |
| Schmelzpunkt | 53℃ [MER06] |
| Dichte | 2.49 |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Löslichkeit | Water (Slightly)Soluble in water. Insoluble in alcohol. |
| Aggregatzustand | Powder |
| Farbe | White |
| Wichte | 2.49 |
| Merck | 14,8696 |
| Kosmetik-Inhaltsstoffe Funktionen | BUFFERINGCHELATINGANTICAKING |
| InChI | InChI=1S/3Na.H3O9P3/c1-10(2)7-11(3,4)9-12(5,6)8-10/h(H,1,2)(H,3,4)(H,5,6)/q3*+1/p-3 |
| InChIKey | UGTZMIPZNRIWHX-UHFFFAOYSA-K |
| SMILES | P1([O-])(=O)OP(OP([O-])(=O)O1)([O-])=O.[Na+].[Na+].[Na+] |
| CAS Datenbank | 7785-84-4(CAS DataBase Reference) |
| EPA chemische Informationen | Sodium trimetaphosphate (7785-84-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (132 of 132) of all reports.Not ClassifiedAggregated GHS information provided per 132 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Metaphosphoric acid (H3P3O9), trisodium saltMetaphosphoric acid (H3P3O9), sodium salt (1:3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Metaphosphoric acid (H3P3O9), sodium salt (1:3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 10-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/5327Metaphosphoric acid (H3P3O9), trisodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Weitere Sicherheitsinformationen | IMAP assessments - Metaphosphoric acid (H3P3O9), trisodium salt: Human health tier I assessment |
| Gefahrenübersicht | Emergency treatment: Inorganic phosphatesInorganic phosphates can cause diarrhea, hyperphosphatemia, and hypocalcemia after ingestionAn adult died after receiving four sodium phosphate enemas within 24 hourshe had electrolyte abnormalities and died from cardiac arrest[HSDB] Oral LD50 (mouse) = 10300 mg/kg[RTECS] May cause irritation[MSDSonline] |
| FDA-Anforderungen | Conditions of use: This substance is generally recognized as safe when used in accordance with good manufacturing practice.Sodium metaphosphate used as a sequestrant in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice. |
| CERCLA-Meldepflichtmengen | Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 454 kg. The toll free telephone number of the NRC is (800) 424-8802In the Washington metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.6 (section IV. D.3.b).Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 5000 lb or 2270 kg. The toll free number of the NRC is (800) 424-8802In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b). |
| Hazard Classes and Categories | Not Classified |
| Brandbekämpfungsverfahren | If material /sodium phosphate, tribasic/ is involved in a fire: extinguish fire using agent suitable for type of surrounding fire (material itself does not burn or burns with difficulty). Keep material out of water sources and sewers, building dikes to contain flow as necessary. |
| Entsorgungsverfahren | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
| Personal Protective Equipment (PPE) | US BUREAU OF MINES TOXIC DUST MASKPROTECTIVE GLOVES, CHEMICAL-TYPE GOGGLES, FULL-COVER CLOTHING. |
| Toxizitätsübersicht | The CIR Expert Panel concluded that the following 31 ingredients are safe in the present practices of use and concentration in cosmetics as described in this safety assessment, when formulated to be non-irritating...Sodium Trimetaphosphate...Safe for use in cosmetics, with qualificationsIDENTIFICATION AND USE: Trisodium trimetaphosphate exists as colorless efflorescent triclinic rhombohedral prisms. It is used in tooth polishing agents and used in synthetic dairy products. It is used in detergent processing, water softeners, sequesterants, emulsifiers, food additives, textile processing, and laundering. HUMAN EXPOSURE AND TOXICITY: Disodium salts such as the metaphosphates are toxic because of their excess alkalinity rather than from sodium excess. ANIMAL STUDIES: Rats fed diets containing this chemical, high doses had adverse effects on kidneys. Growth retardation was also observed in rats fed this chemical in diets. |
| Human Toxicity Excerpts | ... /SODIUM/ SALTS, SUCH AS METAPHOSPHATES, ARE TOXIC PROBABLY BECAUSE OF THEIR EXCESS ALKALINITY RATHER THAN FROM SIMPLE SODIUM EXCESS. |
| Non-Human Toxicity Excerpts | /IN RAT/ DIETS CONTAINING 0.2, 2.0, & 10% SODIUM TRIMETAPHOSPHATE ... ONLY THE HIGHEST LEVELS WERE FOUND TO HAVE ADVERSE EFFECTS ON KIDNEYSNONE OF THE LOWER LEVELS HAD ANY ADVERSE EFFECTS. ... A FURTHER STUDY OF 100 RATS FED DIETS CONTAINING 0.1, 1.0, & 10% SODIUM TRIMETAPHOSPHATE RESULTED IN RETARDED GROWTH FOR ALL RATS WHEN THE DIETS CONTAINED 10% & A REDUCTION IN GROWTH RATE FOR THOSE MALE RATS RECEIVING 1%.EXPTL USE: THE LEVEL OF CARIES WAS LOWER IN RATS FED CARIES-CONDUCIVE DIETS CONTAINING 0.5 OR 1% TRIMETAPHOSPHATE THAN IN CONTROLS FED THE DIET ALONE, REGARDLESS OF WHETHER THE TRIMETAPHOSPHATE WAS FED IN THE DIET CONTINUOUSLY OR DURING ALTERNATING 24 HR PERIODS.EXPTL USE: SODIUM METAPHOSPHATE INHIBITED EXPTL CALCULI FORMATION IN RAT BLADDER IN VIVO. THIS INHIBITORY EFFECT WAS DUE TO INCREASED URINARY EXCRETION OF PYROPHOSPHATES & PHOSPHORYLATED POLYPEPTIDES, WITH THEIR SUBSEQUENT CRYSTAL POISONING EFFECT.EXPTL USE: THE INCLUSION OF SODIUM TRIMETAPHOSPHATE IN A HIGH-SUCROSE DIET DECREASED IN THE LEVAN HYDROLASE ACTIVITY OF PLAQUE, POPULATIONS OF TOTAL VIABLE MICROORGANISMS & STREPTOCOCCI, & URINE CALCIUM LEVEL. AN INCREASE IN THE FRUCTOSYLTRANSFERASE ACTIVITY OF PLAQUE, IN POPULATIONS OF VEILLONELLA & STREPTOCOCCUS SANGUIS, & IN URINE PHOSPHORUS LEVELS ALSO OCCURRED.EXPTL USE: SODIUM, CALCIUM, & MAGNESIUM TRIMETAPHOSPHATES WERE EQUALLY CAPABLE OF INHIBITING CARIOUS LESIONS IN RAT OCCLUSAL SULCI. |
| RAIS Toxicity Values | 1PPRTV Current4 |
| Non-Human Toxicity Values | LD50 Rat ip 3650 mg/kg |
| Hazard Quotient Level 0.1 or Cancer Risk Level 1E-06 | 7.80e+041.20e+062.00e+041.5E+01(G)1.00e+00Volatile |
| Hazard Quotient Level 3 or Cancer Risk Level 1E-04 | 2.30e+053.50e+066.00e+041.5E+01 (G)1.00e+00Volatile |
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 3077 9 / PGIII |
| Zollcode | 28353190 |
| RTECS-Nr. | OY4025000 |
| Sicherheitshinweise (S) | 44 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrstoffdaten | 7785-84-4(Hazardous Substances Data) |
Anwendungen & Verwendung
Verwenden
Sodium Trimetaphosphate works as the crosslinking agent in the cross-linked amylase-resistant starch.