1,2,3-Tris(2,3-epoxypropoxy)propan

Warning

H315 (97.1%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 70 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Chemical: Oxirane, 2,2',2''-[1,2,3-propanetriyltris(oxymethylene)]tris-

TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.

Status: Active Update: 16-03-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/34059

Triglycidylglycerol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Cool fire exposed containers with water... fight fire with chemical foam, water, carbon dioxide, or dry chemicals. /Glycidyl ethers/

Dry chemical extinguishers should be placed in areas where glycidyl ethers are loaded, unloaded, or stored. /Glycidyl ethers/

Should be stored in a cool place where they will be protected from extreme temperatures. /Glycidyl ethers/

Keep away from acids, bases, and salts. /Glycidyl ethers/

Leather articles such as belts or shoes which become contaminated with glycidyl ethers shall be discarded. /Glycidyl ethers/

Use only spark-proof tools in areas where glycidyl ethers are in use. /Glycidyl ethers/

No consumption of food or beverages in areas where glycidyl ethers are in use. /Glycidyl ethers/

Safety showers and eyewash fountains shall be provided in appropriate areas. /Glycidyl ethers/

For more Preventive Measures (Complete) data for TRIGLYCIDYLGLYCEROL (7 total), please visit the HSDB record page.

Protective clothing... gloves, aprons, suits, boots and face shields (8 in minimum) should be made of materials impervious to glycidyl ethers, eg., milled butyl rubber or polyvinyl alcohol... such clothing should be fire-resistant. /Glycidyl ethers/

Chemical safety goggles (splash proof) should be worn. /Glycidyl ethers/

Gloves shall be of sufficient length to protect forearms of workers. /Glycidyl ethers/

Unacceptable glove material include: natural rubber (latex), neoprene-natural rubber (latex), milled neoprene, neoprene with nylon, milled Buna-N, vinyl and polyethylene (disposable), and polyvinyl chloride. /Glycidyl ethers/

Comprehensive medical and work histories...Emphasis directed to prior exposure to glycidyl ethers or other vinyl derivatives... History of sensitivities, allergies, and reproductive events. Physical examination.. Attention to the skin, eyes, and mucous membranes. Clinical tests: total and differential leukocyte counts, urinalysis, pulmonary function tests, tests of manual dexterity, and visual-motor coupling. /Glycidyl ethers/

THE MUTAGENIC ACTIVITIES OF EPOXIDE COMPOUNDS, INCLUDING GLYCERYL GLYCIDYL ETHER, WERE EXAMINED BY THE DNA REPAIR & REVERSION TESTS WITH STRAINS OF ESCHERICHIA COLI & SALMONELLA TYPHIMURIUM. WHEREIN SOME EPOXIDE COMPOUNDS OF RELATIVELY LOW MOLECULAR WEIGHT INDUCE MUTATION, THE MUTAGENICITY OF THE EPOXIDE RESINS MIGHT BE INFLUENCED BY THEIR SOLUBILITIES &(OR) TRANSPORTATION THROUGH CELLULAR MEMBRANES.

Glycidyl ethers are capable of producing testicular atrophy and hemopoietic abnormalities in various species of laboratory animals. /Glycidyl ethers/

Intramuscular injections of glycidyl ethers in Long-Evans rats ... produced ... up to 400 mg/kg ... CNS effects including muscular incoordination reduced motor activity, agitation, excitement, deep depression, /deep/ sleep, and coma. ... Route of administration ... important in the onset, duration, and severity of CNS effects. ... /Glycidyl ethers/

Glycidyl ethers produce widespread systemic effects ... necrosis, edema, inflammation, hyperemia, hemorrhaging, and tissue degeneration. /Glycidyl ethers/

Inhalation of glycidyl ethers in the manufacture or utilization of adhesives, tooling and molding operations, and the application of protective coatings containing epoxy resins. /Glycidyl ethers/

Skin contact in handling glycidyl ethers and uncured resins. /Glycidyl ethers/

Used as reactive diluent and to make epoxy resins flexible; [HSDB]

Plastic Composites Manufacturing [Category: Industry]

Used as reactive diluents in epoxy manufacture and/or utilization systems. /Glycidyl ethers/

REACTIVE DILUENT & FLEXIBILIZER FOR EPOXY RESINS

(1979) No Data

(1981) No Data

(1979) No Data

(1981) No Data

(1979) AT LEAST 4.54X10+6 GRAMS

(1981) No Data