Ciprofibrat

Ciprofibrate

HCID 2763CAS 52214-84-3
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Grundinformationen

Standard-SMILES
CC(C)(Oc1ccc(C2CC2(Cl)Cl)cc1)C(=O)O
InChIKey
KPSRODZRAIWAKH-UHFFFAOYSA-N
Summenformel
C13H14Cl2O3
Durchschnittliche Molmasse
289,15 g/mol
Monoisotopische Masse
288,03199967

Überblick

Ciprofibrate is a monocarboxylic acid, an organochlorine compound and a member of cyclopropanes. It has a role as an antilipemic drug.

Namen und Bezeichner

Bevorzugter Name
Ciprofibrate
IUPAC
2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
Lokaler Name
Ciprofibrat
Englischer Name
Ciprofibrate
Summenformel
C13H14Cl2O3
Molmasse
289.15

Namen und Synonyme

Ciprofibrate52214-84-32-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acidCiprofibratumCiprofibratoModalimWin-35833WIN 35833DTXSID8020331Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-NSC-759617
Weitere Namen anzeigen
CiprobrateCiprofibric acidCipmlCiprolLipanorCiprofibrate >Ciprofibrate CRS
F8252JGO9S2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acidPropanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-DTXCID20331CHEBI:50867Hyperlipen2-[p-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropionic acidRefChem:577246

Datenbank-Bezeichner

CAS
52214-84-3
PubChem CID
2763
DTXSID
DTXSID8020331
ChEMBL
CHEMBL557555
ChEBI
CHEBI:50867
UNII
F8252JGO9S
EC Number
257-744-6
Nikkaji
J10.383G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
3,4
Polarare Oberfläche (TPSA)
46,5 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
4
Schwere Atome
18

Experimentelle und physikochemische Eigenschaften

Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section171.9 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID8020331]

Physikochemische Eigenschaften

Schmelzpunkt
114 · 114-116°
Siedepunkt
401.74 °C · 401.74°C (rough estimate)
Dichte
1.2576 · 1.2576 (rough estimate)
Brechungsindex
1.5209 · 1.5209 (estimate)
storage temp.
2 · 2-8°C
Löslichkeit
Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in toluene.

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H350 (95%): May cause cancer [Danger Carcinogenicity]

P203, P280, P318, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Hazard Classes and CategoriesCarc. 1B (95%)

Toxikologische Informationen

Drug Induced Liver Injury · 4 Einträge

Drug-Induced Liver Injury Severity and Toxicity (DILIst)

ciprofibrate

DILI Positive

DOI:10.1016/j.drudis.2019.09.022

Sicherheitsdaten

wgk
3
hs_code
29189900
RTECS-Nr.
UF0880000
risk_code
45
hazard_code
T
safety_code
53-22-36/37/39-45

Chemie und Industrie

Pharmakologische Informationen

ATC Code · 3 Einträge

C10AB08

C - Cardiovascular system

QC - Cardiovascular system

MeSH Pharmacological Classification · 2 Einträge

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.

A class of nongenotoxic CARCINOGENS that induce the production of hepatic PEROXISOMES and induce hepatic neoplasms after long-term administration.

Anwendungen · 2 Einträge

BeschreibungCiprofibrate is a potent, long-acting hypolipidemic agent related to clofibrate, bezafibrate and fenofibrate. It is effective in types IIa, IIb, IIX and IV hyperlipoproteinemias, and produces a beneficial elevation of the anti-atherogenic HDL.

VerwendenCiprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]

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