Hexamethylene Bisacetamide

HCID 3616CAS 3073-59-4

Grundinformationen

Standard-SMILES
CC(=O)NCCCCCCNC(C)=O
InChIKey
BNQSTAOJRULKNX-UHFFFAOYSA-N
Summenformel
C10H20N2O2
Durchschnittliche Molmasse
200,28 g/mol
Monoisotopische Masse
200,15247788

Überblick

N-(6-acetamidohexyl)acetamide is a member of acetamides.

Namen und Bezeichner

Bevorzugter Name
Hexamethylene Bisacetamide
IUPAC
N-(6-acetamidohexyl)acetamide
Englischer Name
Hexamethylene bisacetamide
Summenformel
C10H20N2O2
Molmasse
200.28

Namen und Synonyme

3073-59-4Hexamethylene bisacetamideHexamethylenebisacetamideN,N'-HexamethylenebisacetamideHexamethylenediacetamidediacetyldiaminohexaneNSC-95580ACETAMIDE, N,N'-HEXAMETHYLENEBIS-NSC 95580N,N'-diacetyl-1,6-hexanediamineN,N'-1,6-HexanediylbisacetamideNSC95580
Weitere Namen anzeigen
N,N'-(Hexane-1,6-diyl)diacetamideN,N′1,6-DIACETAMIDOHEXANE1,6-HexanebisacetamideHEXAMETHYLENE BISCETAMIDE
LA133J59VUDTXSID2041044N, N'-DiacetylhexamethylenediamineAcetamide, N,N'-1, 6-hexanediylbis-N-{6-[(1-hydroxyethylidene)amino]hexyl}ethanimidic acidhexamethylen bisacetamideN-(6-((1-hydroxyethylidene)amino)hexyl)ethanimidic acidRefChem:786209

Datenbank-Bezeichner

CAS
3073-59-4
PubChem CID
3616
DTXSID
DTXSID2041044
ChEMBL
CHEMBL291481
ChEBI
CHEBI:125472
UNII
LA133J59VU
Nikkaji
J227.810C

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,3
Polarare Oberfläche (TPSA)
58,2 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
7
Schwere Atome
14

Experimentelle und physikochemische Eigenschaften

Solubility · 6 Einträge

H2O > 50 (mg/mL)

pH 4 Acetate buffer > 50 (mg/mL)

pH 9 Carbonate buffer > 50 (mg/mL)

0.1 N NaOH > 50 (mg/mL)

0.1 N HCL > 50 (mg/mL)

10% Ethanol > 50 (mg/mL)

Stability/Shelf Life · 1 Eintrag

Bulk: A sample stored at 60°C in the dark for 30 days retained 99 2% of its potency (GC). Solution: Samples were dissolved in water at a concentration of 20 mg/mL and stored in clear glass containers at room temperatures under normal laboratory light for 9 days. The sample retained 98 2% of its potency (GC).

Physikochemische Eigenschaften

Schmelzpunkt
128 · 128-129 °C(lit.)
Siedepunkt
338.01 °C · 338.01°C (rough estimate)
Dichte
0.974 · 0.974
Brechungsindex
1.471 · 1.4710 (estimate)
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
5 %, · water: soluble5%, clear, colorless

Sicherheit und Regulatorisches

Sicherheitsdaten

wgk
3
hs_code
29241990
RTECS-Nr.
AC2976200
risk_code
33
Toxizität
human,TDLo,intravenous,4270mg/kg/10D (4270mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBLOOD: THROMBOCYTOPENIA,Cancer Research. Vol. 47, Pg. 5788, 1987.
safety_code
22-24/25

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Substances that inhibit or prevent the proliferation of NEOPLASMS.

Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.

Anwendungen

VerwendenN,N′-Hexamethylene bis(acetamide) was used as an inducing agent in obtaining mononuclear cells from the peripheral blood (PB) sample by Ficoll-Hypaque gradient separation.

Anbieter50 Anbieter

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