HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hexamethylene Bisacetamide
N,N'-HEXAMETHYLENEBISACETAMIDE · N,N'-(Hexane-1,6-diyl)diacetamide · NSC-95580 · N,N′1,6-DIACETAMIDOHEXANE · 1,6-Hexanebisacetamide · Hexamethylenediacetamide · hexamethylenebisacetamide · HEXAMETHYLENE BISCETAMIDE
Identifikatoren & physikalische Daten
| CAS No. | 3073-59-4 |
|---|---|
| Summenformel | C10H20N2O2 |
| Durchschnittliche Molmasse | 200,28 g/mol |
| Monoisotopische Masse | 200,15247788 g/mol |
| SMILES | CC(=O)NCCCCCCNC(C)=O |
| InChIKey | BNQSTAOJRULKNX-UHFFFAOYSA-N |
| PubChem CID | 3616 |
| ChEMBL | CHEMBL291481 |
| ChEBI | CHEBI:125472 |
| DTXSID | DTXSID2041044 |
Chemische & physikalische Eigenschaften
| XLogP | 0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 58,2 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 14 |
| Formalladung | 0 |
| Komplexität | 161 |
| Löslichkeit | H2O > 50 (mg/mL)pH 4 Acetate buffer > 50 (mg/mL)pH 9 Carbonate buffer > 50 (mg/mL)0.1 N NaOH > 50 (mg/mL)0.1 N HCL > 50 (mg/mL)10% Ethanol > 50 (mg/mL)water: soluble5%, clear, colorlesswater: soluble 5%, clear, colorless |
| Stability/Shelf Life | Bulk: A sample stored at 60°C in the dark for 30 days retained 99 2% of its potency (GC). Solution: Samples were dissolved in water at a concentration of 20 mg/mL and stored in clear glass containers at room temperatures under normal laboratory light for 9 days. The sample retained 98 2% of its potency (GC). |
| Schmelzpunkt | 128-129 °C(lit.) |
| Siedepunkt | 338.01°C (rough estimate) |
| Dichte | 0.974 |
| Brechungsindex | 1.4710 (estimate) |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Aggregatzustand | A solid |
| pKa (Säurekonstante) | 16.20±0.46(Predicted) |
| Farbe | White to off-white |
| BRN | 1775764 |
| InChI | InChI=1S/C10H20N2O2/c1-9(13)11-7-5-3-4-6-8-12-10(2)14/h3-8H2,1-2H3,(H,11,13)(H,12,14) |
| InChIKey | BNQSTAOJRULKNX-UHFFFAOYSA-N |
| SMILES | C(NC(=O)C)CCCCCNC(=O)C |
| CAS Datenbank | 3073-59-4(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 29241990 |
| RTECS-Nr. | AC2976200 |
| R-Sätze (R) | 33 |
| Toxizität | human,TDLo,intravenous,4270mg/kg/10D (4270mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBLOOD: THROMBOCYTOPENIA,Cancer Research. Vol. 47, Pg. 5788, 1987. |
| Sicherheitshinweise (S) | 22-24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
N,N′-Hexamethylene bis(acetamide) was used as an inducing agent in obtaining mononuclear cells from the peripheral blood (PB) sample by Ficoll-Hypaque gradient separation.