6-Amino-o-cresol (HCID 413657)

Namen und Bezeichner

Bevorzugter Name: 6-Amino-o-cresol
IUPAC: 2-amino-6-methylphenol
Englischer Name: 6-Amino-2-methylphenol
Summenformel: C7H9NO
Molmasse: 123.15

Namen und Synonyme

2-amino-6-methylphenol17672-22-96-Amino-2-methylphenol6-Amino-o-cresolPhenol, 2-amino-6-methyl-o-Cresol, 6-amino-6-Methyl-2-aminophenol6-Methyl-o-aminophenolUNII-4N899ESJ5B6-Amino-o-cresol [INCI]4N899ESJ5BDTXSID80170179

Weitere Namen anzeigen

2-methyl-6-aminophenol6- aMinocresolASISCHEM D509546-AMINO-ORTHO-CRESOL2-Amino-6-methylpheno6-Amino-o-methylphenol6-AMINO-O-CRESOL, 99.5%

2A6MP6-Amino-o-creosolRefChem:104199DTXCID9092670605-780-12-Amino-6-methyl-phenolMFCD03788432Amino-hydroxy-methyl-benzol

Datenbank-Bezeichner

CAS: 17672-22-9
PubChem CID: 413657
DTXSID: DTXSID80170179
ChEMBL: CHEMBL5542658
UNII: 4N899ESJ5B
EC Number: 605-780-1
Nikkaji: J1.712.101D

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 1,5
Polarare Oberfläche (TPSA): 46,3 Å²
H-Brücken-Donoren: 2
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 0
Schwere Atome: 9
Formalladung: 0
Komplexität: 94

Physikochemische Eigenschaften

Schmelzpunkt: 86 ℃ · 86℃
Siedepunkt: 232.9 · 232.9±28.0 °C(Predicted)
Dichte: 1.157 · 1.157±0.06 g/cm3(Predicted)
storage temp.: 2 · 2-8°C(protect from light)
pka: 10.1 · 10.10±0.10(Predicted)
Kosmetik-Inhaltsstoffe Funktionen: HAIR DYEING
InChI: 1S/C7H9NO/c1-5-3-2-4-6(8)7(5)9/h2-4,9H,8H2,1H3
InChIKey: ALQKEYVDQYGZDN-UHFFFAOYSA-N
SMILES: Cc1cccc(N)c1O
CAS Datenbank: 17672 · 17672-22-9

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory InformationChemical: Phenol, 2-amino-6-methyl-

Other Safety InformationIMAP assessments - Chemicals with limited data availability that may be used in hair dyes overseas: Human health tier II assessment；IMAP assessments - Phenol, 2-amino-6-methyl-: Environment tier I assessment

Hazard Classes and CategoriesAcute Tox. 4 (100%)；Skin Irrit. 2 (100%)；Eye Irrit. 2A (100%)；STOT SE 3 (100%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The Expert Panel for Cosmetic Ingredient Safety concluded that the available data are insufficient to make a determination of safety for 6-Amino-o-Cresol under the intended conditions of use as a hair dye ingredient.

Safe for use in cosmetics, with qualifications

Regulatorische Informationen

Regulatory InformationChemical: Phenol, 2-amino-6-methyl-

Sicherheitsdaten

wgk: WGK 3
hs_code: 29222990
risk_code: 22-36/37/38
hazard_code: Xn
safety_code: 26
hazard_class: IRRITANT
Speicherklasse: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: 6-Amino-o-Cresol

Use ClassificationCosmetics -> Hair dyeing

Anwendungen · 1 Eintrag

Verwenden6-Amino-2-methylphenol is a colorant that has been classified as a skin sensitizer. It is used in the manufacture of inorganic pigments and other organic compounds, such as dyes and paints. 6-Amino-2-methylphenol absorbs ultraviolet radiation and reacts with chloride to form 2-amino, 6-(chloromethyl) phenol, which has been shown to have subchronic toxicity. This chemical also photodegrades in sunlight, producing free radicals that can damage cells.