HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Amino-o-cresol
2-amino-6-methylphenol · 6-AMINO-O-CRESOL · 2-methyl-6-aminophenol · 6- aMinocresol · ASISCHEM D50954 · 6-AMINO-ORTHO-CRESOL · 2-Amino-6-methylpheno · 6-Amino-o-methylphenol
Identifikatoren & physikalische Daten
| CAS No. | 17672-22-9 |
|---|---|
| Summenformel | C7H9NO |
| Durchschnittliche Molmasse | 123,15 g/mol |
| Monoisotopische Masse | 123,06841391 g/mol |
| SMILES | Cc1cccc(N)c1O |
| InChIKey | ALQKEYVDQYGZDN-UHFFFAOYSA-N |
| PubChem CID | 413657 |
| ChEMBL | CHEMBL5542658 |
| EC No. | 605-780-1 |
| DTXSID | DTXSID80170179 |
Chemische & physikalische Eigenschaften
| XLogP | 1,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 46,3 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 9 |
| Formalladung | 0 |
| Komplexität | 94 |
| Schmelzpunkt | 86℃ |
| Siedepunkt | 232.9±28.0 °C(Predicted) |
| Dichte | 1.157±0.06 g/cm3(Predicted) |
| Lagerbedingungen | 2-8°C(protect from light) |
| pKa (Säurekonstante) | 10.10±0.10(Predicted) |
| Kosmetik-Inhaltsstoffe Funktionen | HAIR DYEING |
| InChI | 1S/C7H9NO/c1-5-3-2-4-6(8)7(5)9/h2-4,9H,8H2,1H3 |
| InChIKey | ALQKEYVDQYGZDN-UHFFFAOYSA-N |
| SMILES | Cc1cccc(N)c1O |
| CAS Datenbank | 17672-22-9 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Phenol, 2-amino-6-methyl- |
| Weitere Sicherheitsinformationen | IMAP assessments - Chemicals with limited data availability that may be used in hair dyes overseas: Human health tier II assessmentIMAP assessments - Phenol, 2-amino-6-methyl-: Environment tier I assessment |
| Hazard Classes and Categories | Acute Tox. 4 (100%)Skin Irrit. 2 (100%)Eye Irrit. 2A (100%)STOT SE 3 (100%) |
| Toxizitätsübersicht | The Expert Panel for Cosmetic Ingredient Safety concluded that the available data are insufficient to make a determination of safety for 6-Amino-o-Cresol under the intended conditions of use as a hair dye ingredient.Safe for use in cosmetics, with qualifications |
| Wassergefährdungsklasse (WGK) | WGK 3 |
| Zollcode | 29222990 |
| R-Sätze (R) | 22-36/37/38 |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 26 |
| Gefahrenklasse | IRRITANTAcute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
6-Amino-2-methylphenol is a colorant that has been classified as a skin sensitizer. It is used in the manufacture of inorganic pigments and other organic compounds, such as dyes and paints. 6-Amino-2-methylphenol absorbs ultraviolet radiation and reacts with chloride to form 2-amino, 6-(chloromethyl) phenol, which has been shown to have subchronic toxicity. This chemical also photodegrades in sunlight, producing free radicals that can damage cells.