5-Oxo-D-prolin

D-Pyroglutamic acid

HCID 439685CAS 4042-36-8
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
O=C1CC[C@H](C(=O)O)N1
InChIKey
ODHCTXKNWHHXJC-GSVOUGTGSA-N
Summenformel
C5H7NO3
Durchschnittliche Molmasse
129,11 g/mol
Monoisotopische Masse
129,04259308

Überblick

5-oxo-D-proline is the D-enantiomer of 5-oxoproline. It has a role as a metabolite. It is a 5-oxoproline and a D-proline derivative. It is a conjugate acid of a 5-oxo-D-prolinate. It is an enantiomer of a 5-oxo-L-proline.

Namen und Bezeichner

Bevorzugter Name
D-Pyroglutamic acid
IUPAC
(2R)-5-oxopyrrolidine-2-carboxylic acid
Lokaler Name
5-Oxo-D-prolin
Englischer Name
D-Pyroglutamic acid
Summenformel
C5H7NO3
Molmasse
129.11

Namen und Synonyme

D-Pyroglutamic acid4042-36-85-oxo-D-proline(2R)-5-oxopyrrolidine-2-carboxylic acidD-Proline, 5-oxo-D-Pidolic acid(+)-Pyroglutamic acid(+)-Pidolic acidD-5-Pyrrolidone-2-carboxylic acidD-5-OxoprolineEINECS 223-735-0CHEBI:16924
Weitere Namen anzeigen
H-D-PYR-OHD-pyroglutamateD-PyrogD-PyrogL
DTXSID10193432RefChem:584412DTXCID20115923(2R)-5-oxopyrrolidine-2-carboxylic acid;5-oxo-D-proline223-735-0(R)-5-Oxopyrrolidine-2-carboxylic AcidD-Pyr-OH(R)-(+)-2-Pyrrolidone-5-carboxylic acid

Datenbank-Bezeichner

CAS
4042-36-8
PubChem CID
439685
DTXSID
DTXSID10193432
ChEMBL
CHEMBL1235172
ChEBI
CHEBI:16924
UNII
TQP297C4HN
EC Number
223-735-0
Nikkaji
J53.019K

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-0,8
Polarare Oberfläche (TPSA)
66,4 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
1
Schwere Atome
9

Experimentelle und physikochemische Eigenschaften

CosmeticsPersonal care product
Collision Cross Section124.6 Ų [M-H]-

Physikochemische Eigenschaften

Schmelzpunkt
155 · 155-162 °C
Siedepunkt
239.15 °C · 239.15°C (rough estimate)
Dichte
1.3816 · 1.3816 (rough estimate)
Brechungsindex
10 ° · 10 ° (C=5, H2O)
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
Dimethylformamide, DMSO (Slightly), Methanol (Slightly), Water

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationD-Proline, 5-oxo-: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheitsdaten

wgk
3
hs_code
29339900
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36-37/39
Speicherklasse
11 - Combustible Solids

Chemie und Industrie

Anwendungen · 1 Eintrag

BeschreibungD-Pyroglutamic acid, also known as 5-oxo-D-proline, is a metabolite of D-glutamate. It is formed from D-glutamate by D-glutamate cyclase. The levels of D-pyroglutamic acid are increased in the urine of patients with nascent metabolic syndrome and the plasma of patients with end-stage renal disease.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
山东海舟生物工程有限公司130-0567-0367 13006570367 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: D-Pyroglutamic acid is the D-enantiomer of 5-oxoproline. It has a role as a metabolite. It is a D-proline derivative and a 5-oxoproline. It is a conjugate acid of a 5-oxo-D-prolinate. It is an enantiomer of a 5-oxo-L-proline.

Zugehörige Reaktionen

19
Reaktionsaufzeichnung erstellen

Verknüpfte Notizen

Wird geladen…