Grundinformationen
- Standard-SMILES
NCCc1cc(O)c(O)cc1O- InChIKey
DIVDFFZHCJEHGG-UHFFFAOYSA-N- Summenformel
- C8H11NO3
- Durchschnittliche Molmasse
- 169,18 g/mol
- Monoisotopische Masse
- 169,07389321
Überblick
6-hydroxydopamine is a solid. Used as a pharmacological agent.
Namen und Bezeichner
- Bevorzugter Name
- 6-Hydroxydopamine
- IUPAC
- 5-(2-aminoethyl)benzene-1,2,4-triol
- Lokaler Name
- Oxidopamin
- Englischer Name
- oxidopamine
- Summenformel
- C8H11NO3
- Molmasse
- 169.18
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
1199-18-4- PubChem CID
- 4624
- DTXSID
DTXSID0036768- ChEMBL
CHEMBL337702- ChEBI
CHEBI:78741- UNII
- 8HW4YBZ748
- EC Number
- 214-842-3
- Nikkaji
- J126K
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,2
- Polarare Oberfläche (TPSA)
- 86,7 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 12
- Formalladung
- 0
- Komplexität
- 142
Experimentelle und physikochemische Eigenschaften
Physical Description
6-hydroxydopamine is a solid. Used as a pharmacological agent.
Solid
Collision Cross Section
143 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
143.2 Ų [M+H]+
Physikochemische Eigenschaften
- Siedepunkt
- 298.46 °C · 298.46°C (rough estimate)
- Dichte
- 1.2435 · 1.2435 (rough estimate)
- Brechungsindex
- 1.51 · 1.5100 (estimate)
- EPA chemische Informationen
- 6 · 6-Hydroxydopamine (1199-18-4)
Sicherheit und Regulatorisches
Gefahrenhinweise
Reactivity Profile
Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Sicherheit und Schutzausrüstung
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Personal Protective Equipment (PPE)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.
Anwendungen
VerwendenAdrenergic (ophthalmic).
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter5 Anbieter
Ergänzende Hinweise
DefinitionChEBI: A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Pa kinson's disease).
Zugehörige Reaktionen
Verknüpfte Notizen
Wird geladen…