2-Brom-3'-chlorpropiophenon

alpha-Bromo-3-chloropropiophenone

HCID 4992116CAS 34911-51-8
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Grundinformationen

Standard-SMILES
CC(Br)C(=O)c1cccc(Cl)c1
InChIKey
OFNMQTRHMBQQEA-UHFFFAOYSA-N
Summenformel
C9H8BrClO
Durchschnittliche Molmasse
247,51 g/mol
Monoisotopische Masse
245,94470466

Namen und Bezeichner

Bevorzugter Name
alpha-Bromo-3-chloropropiophenone
IUPAC
2-bromo-1-(3-chlorophenyl)propan-1-one
Lokaler Name
2-Brom-3'-chlorpropiophenon
Englischer Name
2-Bromo-3'-chloropropiophenone
Summenformel
C9H8BrClO
Molmasse
247.52

Namen und Synonyme

34911-51-82-Bromo-3'-chloropropiophenone2-bromo-1-(3-chlorophenyl)propan-1-one2-Bromo-1-(3-chlorophenyl)-1-propanone3OP1CI6QQX1-Propanone, 2-bromo-1-(3-chlorophenyl)-EINECS 252-282-1ALPHA-BROMO-3-CHLOROPROPIOPHENONE2-BROMO-3-CHLOROPROPIOPHENONEBROMOCHLOROPROPIO PHENONEDTXSID10956382.ALPHA.-BROMO-M-CHLOROPROPIOPHENONE
Weitere Namen anzeigen
Bupropion Related Compound GDK7492B3CP2-Bromo BupropionBupropion Impurity 5Bupropion Impurity 42Bupropion impurity M1-9
BROMOCHLOROPROPIO PHENONE [USP IMPURITY]BROMOCHLOROPROPIO PHENONE (USP IMPURITY)RefChem:555412DTXCID501384347ALPHA-BROMO-M-CHLOROPROPIOPHENONE.ALPHA.-BROMO-3-CHLOROPROPIOPHENONE3'-CHLORO-2-BROMOPROPIOPHENONEBupropion 2-Bromo Impurity

Datenbank-Bezeichner

CAS
34911-51-8
PubChem CID
4992116
DTXSID
DTXSID10956382
UNII
3OP1CI6QQX
EC Number
252-282-1
Nikkaji
J289.863B

Eigenschaften

Berechnete Struktureigenschaften

XLogP
3,7
Polarare Oberfläche (TPSA)
17,1 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
1
Frei drehbare Bindungen
2
Schwere Atome
12

Physikochemische Eigenschaften

Siedepunkt
148 · 148-148.5 °C(Press: 9 Torr)
Dichte
1.532 · 1.532
Brechungsindex
1.577 · 1.5770
storage temp.
Refrigerator, Under Inert Atmosphere
Löslichkeit
Soluble in acetonitrile, chloroform, dichloromethane and ethyl acetate.
Aggregatzustand
Liquid

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (83.3%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazard Classes and CategoriesSkin Irrit. 2 (83.3%)

Sicherheitsdaten

wgk
WGK 3
hs_code
2914790000
hazard_class
IRRITANT
Speicherklasse
12 - Non Combustible Liquids
Hazard Classifications
Skin Irrit. 2Skin Sens. 1B

Chemie und Industrie

Anwendungen

Verwenden2-Bromo-3'-chloropropiophenone is used as an important intermediate for raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
Ergänzende Hinweise · 1 Eintrag

Definition2-Bromo-3'-chloropropiophenone (BCP), a yellow oil, is an intermediate used in the synthesis of bupropion and is also found as an impurity of bupropion hydrochloride. Bupropion is a second-generation antidepressant that was originally approved by the United States Food and Drug Administration (FDA) in 1985. It is a norepinephrine and dopamine transporter inhibitor and an antagonist at neuronal nicotinic acetylcholine receptors. Bupropion is also approved for smoking cessation[1].

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