Nedocromil Sodium

HCID 50295

Grundinformationen

CAS
69049-74-7
Standard-SMILES
CCCc1c2oc(C(=O)[O-])cc(=O)c2cc2c(=O)cc(C(=O)[O-])n(CC)c12.[Na+].[Na+]
InChIKey
JQEKDNLKIVGXAU-UHFFFAOYSA-L
Summenformel
C19H15NNa2O7
Durchschnittliche Molmasse
415,3 g/mol
Monoisotopische Masse
415,06439038

Namen und Bezeichner

Bevorzugter Name
Nedocromil Sodium
IUPAC
disodium;9-ethyl-4,6-dioxo-10-propylpyrano[3,2-g]quinoline-2,8-dicarboxylate
Englischer Name
NEDOCROMIL SODIUM
Summenformel
C19H18NNaO7
Molmasse
395.34

Namen und Synonyme

NEDOCROMIL SODIUM69049-74-7TiladeAlocrilTayledFPL 59002KPRapitilTilarinNedocromil disodium saltFPL-59002KPET8IF4KS1TCHEBI:7493
Weitere Namen anzeigen
NEDOCROMIL SODIUM###Nedocromil4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylicacid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, sodium salt
4H-Pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium saltDTXSID00219115RefChem:57534DTXCID20141606620-501-3Sodium 9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylateNedocromil sodium [USAN]UNII-ET8IF4KS1T

Datenbank-Bezeichner

CAS
69049-74-7
PubChem CID
50295
DTXSID
DTXSID00219115
ChEMBL
CHEMBL915
ChEBI
CHEBI:7493
UNII
ET8IF4KS1T
EC Number
620-501-3
Nikkaji
J357.902F

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
127 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
8
Frei drehbare Bindungen
3
Schwere Atome
29

Physikochemische Eigenschaften

storage temp.
2 · Inert atmosphere,2-8°C
Löslichkeit
2 O: · H2O: soluble20mg/mL, clear
Aggregatzustand
powder
Farbe
, white to beige to brown
Wasserlöslichkeit
2 O: · H2O: 20mg/mL, clear
InChI
1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 16.7% (1 of 6) of reports.

Warning

H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (83.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (33.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 6 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 6 reports by companies.;There are 2 notifications provided by 5 of 6 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Other Safety Information · 1 Eintrag

IMAP assessments - 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt: Human health tier I assessment;IMAP assessments - 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt: Environment tier I assessment

Hazard Classes and CategoriesSkin Irrit. 2 (33.3%);Eye Irrit. 2 (83.3%);STOT SE 3 (33.3%)

Sicherheitsdaten

wgk
3
Speicherklasse
11 - Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 4 Einträge

Substances that reduce or suppress INFLAMMATION.

Compounds that prevent the release of inflammatory mediators from MAST CELLS.

Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)

Drugs that are used to treat asthma.

Anwendungen

BeschreibungNedocromil sodium is an antiallergic agent with broader mast cell stabilizing properties than related cromolyn sodium. Administered as an aerosol, it is useful in the treatment of bronchial asthma and related diseases.

VerwendenNedocromil Sodium (Technical Grade) is a medication considered as mast cell stabilizer which act to prevent wheezing, shortness of breath, and other breathing problems caused by asthma.

Anbieter30 Anbieter

陕西缔都新材料有限公司81124267 17392282731 · [email protected]
合肥曼奇诺生物医药技术有限公司19719236623 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

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