HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Eprosartan Mesylate
Eprosartan Myslate · Eposartan mesylate · EPROSARTAN MESYLATE · Monomethanesulfonate · EprosartanMesylate>Eprosartan mesylate, >=99% · Eprosartan Methanesulfonate · Eprosartan mesylate USP/EP/BP · Sunitinib and its interMediate
Identifikatoren & physikalische Daten
| CAS No. | 144143-96-4 |
|---|---|
| Summenformel | C24H28N2O7S2 |
| Durchschnittliche Molmasse | 520,6 g/mol |
| Monoisotopische Masse | 520,13379358 g/mol |
| SMILES | CCCCc1ncc(/C=C(\Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1.CS(=O)(=O)O |
| InChIKey | DJSLTDBPKHORNY-XMMWENQYSA-N |
| PubChem CID | 5282474 |
| ChEMBL | CHEMBL1200987 |
| ChEBI | CHEBI:48409 |
| DTXSID | DTXSID7044217 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 183 |
|---|---|
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 9 |
| Frei drehbare Bindungen | 10 |
| Schwere Atome | 35 |
| Formalladung | 0 |
| Komplexität | 711 |
| Schmelzpunkt | 248-250° |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Löslichkeit | DMSO: >10mg/mL |
| Aggregatzustand | powder |
| Farbe | white to off-white |
| Merck | 14,3635 |
| Hauptanwendungen | pharmaceutical (small molecule) |
| InChIKey | DJSLTDBPKHORNY-XMMWENQYSA-N |
| SMILES | S(O)(=O)(=O)C.C(C1C=CC(C(=O)O)=CC=1)N1C(=NC=C1/C=C(/C(=O)O)\CC1SC=CC=1)CCCC |
| CAS Datenbank | 144143-96-4(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Drug Induced Liver Injury | Drug Induced Liver Injury Rank (DILIrank 2.0)Eprosartan mesylateAmbiguous-DILI-concern3Adverse reactionsDOI:10.1016/j.drudis.2016.02.015 |
|---|---|
| Effects During Pregnancy and Lactation | ◉ Summary of Use during LactationEprosartan is no longer marketed in the US. Because no information is available on the use of eprosartan during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.◉ Effects in Breastfed InfantsRelevant published information was not found as of the revision date.◉ Effects on Lactation and Breastmilk |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29349990 |
| RTECS-Nr. | XN0282400 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2 |
Anwendungen & Verwendung
Verwenden
Eprosartan Mesylate is an angiotensin II receptor antagonists. Eprosartan Mesylate is used as an antihypertensive agent.