Grundinformationen
- Standard-SMILES
CCCCCCCC/C=C\CCCCCCCC(N)=O- InChIKey
FATBGEAMYMYZAF-KTKRTIGZSA-N- Summenformel
- C18H35NO
- Durchschnittliche Molmasse
- 281,5 g/mol
- Monoisotopische Masse
- 281,27186474
Namen und Bezeichner
- Bevorzugter Name
- Oleamide
- IUPAC
- (Z)-octadec-9-enamide
- Lokaler Name
- Oleamid
- Englischer Name
- Oleamide
- Summenformel
- C18H35NO
- Molmasse
- 281.48
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
301-02-0- PubChem CID
- 5283387
- DTXSID
DTXSID6027137- ChEMBL
CHEMBL15927- ChEBI
CHEBI:116314- UNII
- 7L25QK8BWO
- EC Number
- 206-103-9
- Nikkaji
- J36.613G
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 6,6
- Polarare Oberfläche (TPSA)
- 43,1 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 15
- Schwere Atome
- 20
- Formalladung
- 0
- Komplexität
- 236
Experimentelle und physikochemische Eigenschaften
Melting Point
76 °C
102 - 104 °C
Physical Description
Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals; Other Solid; Dry Powder; Large Crystals
Ivory-colored solid; [HSDB]
Solid
Kovats Retention Index
2375;2397
3265
Physikochemische Eigenschaften
- Schmelzpunkt
- 70 °C · 70°C
- Siedepunkt
- 433.3 · 433.3±24.0 °C(Predicted)
- Dichte
- 0.94 g/cm3 · 0.94 g/cm3
- storage temp.
- -20 °C · -20°C
- Löslichkeit
- Soluble in chloroform (50 mg/ml), ethanol (100 mM), DMSO (~14 mg/ml), and DMF (~14 mg/ml)
- pka
- 16.61 · 16.61±0.40(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- Wasserlöslichkeit
- Insoluble in water.
- Stabilität
- 2 years · Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
- Kosmetik-Inhaltsstoffe Funktionen
- OPACIFYINGVISCOSITY CONTROLLING
- InChI
- 1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
- InChIKey
- FATBGEAMYMYZAF-KTKRTIGZSA-N
- SMILES
- CCCCCCCC\C=C/CCCCCCCC(N)=O
- LogP
- 6.882 · 6.882 (est)
- CAS Datenbank
- 301 · 301-02-0(CAS DataBase Reference)
- NIST chemische Informationen
- 9 · 9-Octadecenamide, (z)-(301-02-0)
- EPA chemische Informationen
- Oleamide (301-02-0)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 42.7% (470 of 1101) of reports.
Warning
H315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H413 (40.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 1101 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 470 of 1101 reports by companies.;There are 7 notifications provided by 631 of 1101 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Regulatory Information
Chemical: 9-Octadecenamide, (Z)-
9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Contact urticarial reaction reported within 20 minutes of open patch test; Emergency treatment: Irritants; [HSDB] Causes mild skin and eye irritation in rabbits; Not considered sensitizing to human skin; [IUCLID] Causes changes in motor activity and excitement in acute intraperitoneal toxic-dose studies of rats and mice; [RTECS] A skin and strong eye irritant; May cause an allergic skin reaction; [Aldrich MSDS]
Hazard Classes and Categories
Skin Irrit. 2 (12.1%);Eye Irrit. 2 (12.1%);STOT SE 3 (12.1%);Aquatic Chronic 4 (40.2%)
Serious eye damage/eye irritation - Category 2B
Toxikologische Informationen
Regulatorische Informationen
Regulatory Information
Chemical: 9-Octadecenamide, (Z)-
9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard
Sicherheitsdaten
- wgk
- 1
- tsca
- TSCA listed
- hs_code
- 29241990
- risk_code
- 36/37/38-43
- hazard_code
- Xi
- safety_code
- 26-36-37
- Speicherklasse
- 11 - Combustible Solids
- Giftige Stoffe Daten
- 301-02-0(Hazardous Substances Data)
- Hazard Classifications
- Aquatic Chronic 4
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS.
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
Verwendung und Herstellung
Uses
Used as a slip and anti-block agent for extrusion of polyethylene and an additive to wax, printing inks, lubricating oils, and cosmetics; [HSDB] Used as a rubber additive, anti-static agent, dispersion aid, and mold release agent; [IUCLID]
Molding and Core Making [Category: Foundry]
SLIP-AGENT FOR EXTRUSION OF POLYETHYLENE; WAX ADDITIVE; INK ADDITIVE; COSMETICS
SLIP & ANTIBLOCK AGENT FOR PLASTICS-ESP POLYETHYLENE FILM
LUBRICATING OIL ADDITIVE
PRINTING INK ADDITIVE
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 7,000,000 - <8,500,000 lb;2022: 10,000,000 - <25,000,000 lb;2021: 10,000,000 - <25,000,000 lb;2020: 10,000,000 - <25,000,000 lb
(1980) 2.27X10+9 GRAMS (ESTIMATE)
(1981) PROBABLY GREATER THAN 6.81X10+6 GRAMS
General Manufacturing Information
Plastics Material and Resin Manufacturing;Paint and Coating Manufacturing;Adhesive Manufacturing;All Other Chemical Product and Preparation Manufacturing;Rubber Product Manufacturing;Custom Compounding of Purchased Resins;Petroleum Lubricating Oil and Grease Manufacturing;Synthetic Rubber Manufacturing;Plastics Product Manufacturing;Wholesale and Retail Trade
9-Octadecenamide, (9Z)-: ACTIVE
ADOGEN /IS/ TRADEMARK FOR SERIES OF FATTY NITROGEN CHEM INCL AMINES, AMIDES... AVAIL IN VARIOUS GRADES FOR SPECIFIC APPLICATIONS IN FABRIC SOFTENERS, ORE SEPARATION, DETERGENTS, PETROLEUM ADDITIVES, CORROSION INHIBITORS, BACTERICIDES, PRINTING INKS, ANTIBLOCK & SLIP AGENTS... /ADOGEN/
SLIP-EZE /IS/ TRADEMARK FOR A SPECIALLY PREPARED FATTY ACID AMIDE. USED AS SLIP ADDITIVE & AS INTERNAL MOLD-RELEASE ADDITIVE TO POLYETHYLENE.
Anwendungen
VerwendenOleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).
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Ergänzende Hinweise
DefinitionChEBI: A fatty amide derived from oleic acid.
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