Oleamid

Oleamide

HCID 5283387CAS 301-02-0

Grundinformationen

Standard-SMILES
CCCCCCCC/C=C\CCCCCCCC(N)=O
InChIKey
FATBGEAMYMYZAF-KTKRTIGZSA-N
Summenformel
C18H35NO
Durchschnittliche Molmasse
281,5 g/mol
Monoisotopische Masse
281,27186474

Namen und Bezeichner

Bevorzugter Name
Oleamide
IUPAC
(Z)-octadec-9-enamide
Lokaler Name
Oleamid
Englischer Name
Oleamide
Summenformel
C18H35NO
Molmasse
281.48

Namen und Synonyme

Oleamide301-02-0Oleic acid amideOleylamideOleyl amide(Z)-octadec-9-enamideAdogen 739-Octadecenamide, (9Z)-Crodamide OCrodamide ORSlip-ezeArmoslip CP
Weitere Namen anzeigen
ODA9-OCTADECENAMIDEOLEAMIDCIS-9-OCTADECENAMIDE9-Octadecenamide,(Z)-(9Z)-9-Octadecenamide
(Z)-9-OCTADECENAMIDE9Z-octadecenamideArmid O9,10-octadecenamide7L25QK8BWONSC-26987CHEBI:116314RefChem:856476

Datenbank-Bezeichner

CAS
301-02-0
PubChem CID
5283387
DTXSID
DTXSID6027137
ChEMBL
CHEMBL15927
ChEBI
CHEBI:116314
UNII
7L25QK8BWO
EC Number
206-103-9
Nikkaji
J36.613G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
6,6
Polarare Oberfläche (TPSA)
43,1 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
1
Frei drehbare Bindungen
15
Schwere Atome
20

Experimentelle und physikochemische Eigenschaften

Density0.94
Color/FormIVORY-COLORED POWDER
SolubilityINSOL IN WATER; SOL IN ETHER, HOT ALCOHOL
Melting Point · 2 Einträge

76 °C

102 - 104 °C

Vapor Pressure0.0000012 [mmHg]
Physical Description · 3 Einträge

Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals; Other Solid; Dry Powder; Large Crystals

Ivory-colored solid; [HSDB]

Solid

Physikochemische Eigenschaften

Schmelzpunkt
70 °C · 70°C
Siedepunkt
433.3 · 433.3±24.0 °C(Predicted)
Dichte
0.94 g/cm3 · 0.94 g/cm3
storage temp.
-20 °C · -20°C
Löslichkeit
Soluble in chloroform (50 mg/ml), ethanol (100 mM), DMSO (~14 mg/ml), and DMF (~14 mg/ml)
pka
16.61 · 16.61±0.40(Predicted)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 42.7% (470 of 1101) of reports.

Warning

H315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H413 (40.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1101 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 470 of 1101 reports by companies.;There are 7 notifications provided by 631 of 1101 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: 9-Octadecenamide, (Z)-

9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 9-Octadecenamide, (Z)-: Human health tier I assessment
Hazards Summary · 1 Eintrag

Contact urticarial reaction reported within 20 minutes of open patch test; Emergency treatment: Irritants; [HSDB] Causes mild skin and eye irritation in rabbits; Not considered sensitizing to human skin; [IUCLID] Causes changes in motor activity and excitement in acute intraperitoneal toxic-dose studies of rats and mice; [RTECS] A skin and strong eye irritant; May cause an allergic skin reaction; [Aldrich MSDS]

Hazard Classes and Categories · 2 Einträge

Skin Irrit. 2 (12.1%);Eye Irrit. 2 (12.1%);STOT SE 3 (12.1%);Aquatic Chronic 4 (40.2%)

Serious eye damage/eye irritation - Category 2B

Toxikologische Informationen

Human Toxicity ExcerptsOPEN PATCH TEST WITH OLEYLAMIDE (AMIDE OF OLEIC ACID) 0.1% IN ETHANOL ELICITED A STRONG URTICARIAL REACTION IN 20 MIN.

Regulatorische Informationen

Regulatory Information · 3 Einträge

Chemical: 9-Octadecenamide, (Z)-

9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
1
tsca
TSCA listed
hs_code
29241990
risk_code
36/37/38-43
hazard_code
Xi
safety_code
26-36-37

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS.

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

Cellular LocationsExtracellular;Membrane

Verwendung und Herstellung

Uses · 6 Einträge

Used as a slip and anti-block agent for extrusion of polyethylene and an additive to wax, printing inks, lubricating oils, and cosmetics; [HSDB] Used as a rubber additive, anti-static agent, dispersion aid, and mold release agent; [IUCLID]

Molding and Core Making [Category: Foundry]

SLIP-AGENT FOR EXTRUSION OF POLYETHYLENE; WAX ADDITIVE; INK ADDITIVE; COSMETICS

SLIP & ANTIBLOCK AGENT FOR PLASTICS-ESP POLYETHYLENE FILM

LUBRICATING OIL ADDITIVE

PRINTING INK ADDITIVE

U.S. Exports · 2 Einträge

(1979) No Data

(1981) No Data

U.S. Imports · 2 Einträge

(1979) No Data

(1981) No Data

U.S. Production · 3 Einträge

2023: 7,000,000 - <8,500,000 lb;2022: 10,000,000 - <25,000,000 lb;2021: 10,000,000 - <25,000,000 lb;2020: 10,000,000 - <25,000,000 lb

(1980) 2.27X10+9 GRAMS (ESTIMATE)

(1981) PROBABLY GREATER THAN 6.81X10+6 GRAMS

Consumer UsesLubricating agent;Anti-adhesive/cohesive;Surface modifier
Industry UsesAnti-adhesive/cohesive;Lubricating agent;Anti-slip agent;Adhesion/cohesion promoter;Anti-scaling agent;Surface modifier

Anwendungen

VerwendenOleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南长沙恒昌化工有限公司0731-85070388 13217318550
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A fatty amide derived from oleic acid.

Zugehörige Reaktionen

3

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