Arsenous acid
Grundinformationen
- CAS
13464-58-9- Standard-SMILES
O[As](O)O- InChIKey
GCPXMJHSNVMWNM-UHFFFAOYSA-N- Summenformel
- AsH3O3
- Durchschnittliche Molmasse
- 125,944 g/mol
- Monoisotopische Masse
- 125,929814
Überblick
Arsenous acid is an arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom. It is a conjugate acid of an arsenite(1-).
Namen und Bezeichner
- Bevorzugter Name
- Arsenous acid
- IUPAC
- arsorous acid
- Englischer Name
- arsenous acid
- Summenformel
- AsH3O3
- Molmasse
- 125.94
Namen und Synonyme
Arsenous acidarsorous acidTRIHYDROXYARSENITE(III)13464-58-9arsenic trihydroxideH3AsO3As(OH)3935XD1L5K2DTXSID7074828CHEBI:49900RefChem:114198DTXCID3034240
Weitere Namen anzeigen
Arsenous acid (9CI)Arsenous acid (as As)GCPXMJHSNVMWNM-UHFFFAOYSA-NCarbon Dioxide in Nitrogen (Nominal Amount-of-Substance Fraction 500 μmol/mol)
arsenous trioxidediarsonic trioxidearsenic (III) trioxideArsenious acid (H3AsO3)UNII-935XD1L5K2Arsenic (white)trioxoarsenic acidtrihydroxidoarsenic
Datenbank-Bezeichner
- CAS
13464-58-9、15502-74-6- PubChem CID
- 545
- DTXSID
DTXSID7074828- ChEMBL
CHEMBL1236189- ChEBI
CHEBI:49900- UNII
- 935XD1L5K2
- Nikkaji
- J43.679H
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 60,7 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 4
- Formalladung
- 0
- Komplexität
- 8
Experimentelle und physikochemische Eigenschaften
Chemical ClassesMetals -> Arsenic Compounds, Inorganic
Boiling Point465 °C
Physical Description
Solid
V (@25 °C)
Physikochemische Eigenschaften
- Aggregatzustand
- exists only in solution
- pka
- 6.86 · 6.86±0.53(Predicted)
- Farbe
- exists only in solution
- EPA chemische Informationen
- Arsenous acid (13464-58-9)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Gefahrenhinweise
Hazards SummarySee Arsenic and the linked occupational diseases.
Sicherheit und Schutzausrüstung
Exposure Control and Personal ProtectionBiological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;
Minimum Risk LevelAcute Oral: 0.005 mg/kg/day (L134)
Chronic Oral: 0.0003 mg/kg/day (L134)
Chronic Inhalation: 0.01 mg/m3 (L134)
Threshold Limit Values (TLV)0.01 [mg/m3], as As
Permissible Exposure Limit (PEL)0.01 [mg/m3], as As
Protective Action Criteria (PAC)
0.050 [mg/m3]
0.78 [mg/m3]
4.7 [mg/m3]
Immediately Dangerous to Life or Health (IDLH)5.0 [mg/m3], as As
Toxikologische Informationen
Treatment
Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)
Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Chemie und Industrie
Pharmakologische Informationen
Metabolism/Metabolites
Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)
Verwendung und Herstellung
Uses
Arsenic and its compounds are used in pesticides, wood preservatives, paints/pigments, and various metal alloys (electronics). Small amounts of arensic can be found in contaminated air, water, and some meat products, especially seafood. (L2)
Anwendungen
VerwendenPesticides.
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Anbieter1 Anbieter
斯派螺（武汉）药物研发有限公司[email protected]
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