Morphine Hydrochloride

HCID 5464110CAS 52-26-6
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Grundinformationen

Standard-SMILES
CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5.Cl
InChIKey
XCKKIKBIPZJUET-VYKNHSEDSA-N
Summenformel
C17H20ClNO3
Durchschnittliche Molmasse
321,8 g/mol
Monoisotopische Masse
321,1131712

Namen und Bezeichner

Bevorzugter Name
Morphine Hydrochloride
IUPAC
(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol;hydrochloride

Namen und Synonyme

Morphine hydrochloride52-26-6Morphine HClThebamettenMorphine chlorhydrateEpimoreAmpekTheba-IntranVendalMorphinum muriaticummorphine-HClUNII-J28GE0ROVX
Weitere Namen anzeigen
J28GE0ROVXEINECS 200-136-2CHEBI:55340Morphine hydrochloride [USP:JAN]Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, hydrochlorideMorphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5-alpha,6-alpha)-Morphine hydrochloride (USP:JAN)17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol hydrochloride

Datenbank-Bezeichner

CAS
52-26-6
PubChem CID
5464110
ChEMBL
CHEMBL556578
ChEBI
CHEBI:55340
UNII
J28GE0ROVX
EC Number
200-136-2

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
52,9 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
0
Schwere Atome
22

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H301 (37.5%): Toxic if swallowed [Danger Acute toxicity, oral]；H302 (62.5%): Harmful if swallowed [Warning Acute toxicity, oral]；H311 (12.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H315 (12.5%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (50%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (12.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H331 (37.5%): Toxic if inhaled [Danger Acute toxicity, inhalation]；H334 (37.5%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]；H336 (37.5%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic effects]；H361 (50%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]；H361fd (25%): Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]；H362 (62.5%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]

P203, P233, P260, P261, P262, P263, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P361+P364, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 8 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Status: Active Update: 16-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19240

Morphine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety Information · 1 Eintrag

IMAP assessments - Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5.alpha.,6.alpha.)-: Human health tier I assessment；IMAP assessments - Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5.alpha.,6.alpha.)-: Environment tier I assessment

Hazard Classes and CategoriesAcute Tox. 3 (37.5%)；Acute Tox. 4 (62.5%)；Acute Tox. 3 (12.5%)；Skin Irrit. 2 (12.5%)；Skin Sens. 1 (50%)；Eye Irrit. 2 (12.5%)；Acute Tox. 3 (37.5%)；Resp. Sens. 1 (37.5%)；STOT SE 3 (37.5%)；Repr. 2 (50%)；Lact. (62.5%)

Regulatorische Informationen

Regulatory Information · 2 Einträge

Status: Active Update: 16-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/19240

Morphine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

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