Cicletanine

HCID 54910

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Grundinformationen

CAS: 89943-82-8
Standard-SMILES: Cc1ncc2c(c1O)COC2c1ccc(Cl)cc1
InChIKey: CVKNDPRBJVBDSS-UHFFFAOYSA-N
Summenformel: C14H12ClNO2
Durchschnittliche Molmasse: 261,7 g/mol
Monoisotopische Masse: 261,0556563

Überblick

Cicletanine is an organochlorine compound.

Namen und Bezeichner

Bevorzugter Name: Cicletanine
IUPAC: 3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol
Englischer Name: Cicletanine
Summenformel: C14H12ClNO2
Molmasse: 261.7

Namen und Synonyme

CicletanineCycletanide89943-82-8CicletaninaCicletaninumWin 90,000Win-90000BN-1270CHG7QC509Wcicletanide3-(4-chlorophenyl)-6-methyl-1H,3H-furo[3,4-c]pyridin-7-ol3-(4-chlorophenyl)-6-methyl-1H,3H-furo(3,4-c)pyridin-7-ol

Weitere Namen anzeigen

3-(4-Chlorophenyl)-1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-olFuro[3,4-c]pyridin-7-ol, 3-(4-chlorophenyl)-1,3-dihydro-6-methyl-

RefChem:577124C03BX031,3-dihydro-6-methyl-7-hydroxy-3-(4-chlorophenyl)furo(3,4-d)pyridine(A+-)-BN-1270Furo(3,4-c)pyridin-7-ol, 3-(4-chlorophenyl)-1,3-dihydro-6-methyl-Tenstaten3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol(R)-(-)-CICLETANINE

Datenbank-Bezeichner

CAS: 89943-82-8
PubChem CID: 54910
DTXSID: DTXSID70868972
ChEMBL: CHEMBL191886
ChEBI: CHEBI:135078
UNII: CHG7QC509W
EC Number: 630-329-0
Nikkaji: J55.610F

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 2,4
Polarare Oberfläche (TPSA): 42,4 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 3
Frei drehbare Bindungen: 1
Schwere Atome: 18
Formalladung: 0
Komplexität: 294

Experimentelle und physikochemische Eigenschaften

LogP2.34

Physikochemische Eigenschaften

Siedepunkt: 446.3 · 446.3±45.0 °C(Predicted)
Dichte: 1.351 · 1.351±0.06 g/cm3(Predicted)
pka: 5.37 · 5.37±0.40(Predicted)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Gefahrenhinweise

Hazard Classes and CategoriesEye Dam. 1 (100%)

Sicherheitsdaten

Alarmwort: Achtung
Gefahrenhinweise: Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H318

Chemie und Industrie

Pharmakologische Informationen

ATC Code · 2 Einträge

C - Cardiovascular system

QC - Cardiovascular system

MeSH Pharmacological Classification · 3 Einträge

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.

Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Agents that promote the excretion of urine through their effects on kidney function.