2,2'-Dithiodi(ethylammonium)dichlorid
Cystamine Dihydrochloride
Grundinformationen
- CAS
56-17-7- Standard-SMILES
Cl.Cl.NCCSSCCN- InChIKey
YUFRRMZSSPQMOS-UHFFFAOYSA-N- Summenformel
- C4H12N2S2.2ClH
- Durchschnittliche Molmasse
- 225,2 g/mol
- Monoisotopische Masse
- 223,9975462
Überblick
See also: Cystamine (has active moiety).
Namen und Bezeichner
- Bevorzugter Name
- Cystamine Dihydrochloride
- IUPAC
- 2-(2-aminoethyldisulfanyl)ethanamine;dihydrochloride
- Lokaler Name
- 2,2'-Dithiodi(ethylammonium)dichlorid
- Englischer Name
- Cystamine dihydrochloride
- Summenformel
- C4H14Cl2N2S2
- Molmasse
- 225.2
Namen und Synonyme
Cystamine dihydrochloride56-17-7Cystamine HClCystamin dihydrochlorideEthanamine, 2,2'-dithiobis-, dihydrochlorideUSAF CB-342-Aminoethyl disulfide dihydrochloride2,2'-Dithiodi(ethylammonium) dichlorideBis(2-aminoethyl) disulfide dihydrochloride2,2'-Dithio-bis-(ethylamine) dihydrochlorideHydrochloride, CystamineI90T518457
Weitere Namen anzeigen
aed2,2'-disulfanediyldiethanaMine dihydrochlorideusafcb-34CystamineHclcystaminedihclCystamine 2HClTIMTEC-BB SBB003325Cystamine dihydrochLCYSTAMINIUM DICHLORIDE
Dihydrochloride, CystamineDTXSID6058766NSC-39322C2U867X2F7NSC39322RefChem:130221DTXCID7042013200-260-7
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 103 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 10
- Formalladung
- 0
- Komplexität
- 37
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Classes -> Sulfur Compounds
Physical DescriptionSolid; [Merck Index] White odorless hygroscopic powder; [Alfa Aesar MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 217 · 217-220 °C (dec.)(lit.)
- storage temp.
- 30 °C · Store below +30°C.
- Löslichkeit
- 2 O: · H2O: soluble1.0g/10 mL, clear to almost clear, colorless to almost colorless (<5.5 NTU)
- Aggregatzustand
- Crystalline Powder, Crystals or Chunks
- Farbe
- White to yellow
- Biologische Quelle
- synthetic
- Wasserlöslichkeit
- soluble
- Merck
- 14 · 14,2776
- BRN
- 3616850 · 3616850
- Stabilität
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C4H12N2S2.2ClH/c5-1-3-7-8-4-2-6;;/h1-6H2;2*1H
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 53 reports by companies from 7 notifications to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory Information
Chemical: Ethanamine, 2,2'-dithiobis-, dihydrochloride
Ethanamine, 2,2'-dithiobis-, dihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards Summary
Causes depressed renal function tests in acute inhalation studies of rats; Causes somnolence, convulsions, and respiratory depression in oral lethal-dose studies of rats and mice; [RTECS] May cause irritation; Harmful by ingestion; [Alfa Aesar MSDS] See Cystamine.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Toxikologische Informationen
Adverse EffectsNeurotoxin - Other CNS neurotoxin
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29309070
- RTECS-Nr.
- KR7260000
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Drugs used to protect against ionizing radiation. They are usually of interest for use in radiation therapy but have been considered for other purposes, e.g. military.
Chemical agents that react with SH groups. This is a chemically diverse group that is used for a variety of purposes. Among these are enzyme inhibition, enzyme reactivation or protection, and labelling.
Verwendung und Herstellung
Uses
An anti-infective agent most commonly used in the treatment of urinary tract infections. Its anti-infective action derives from the slow release of formaldehyde by hydrolysis at acidic pH. (From Martindale, The Extra Pharmacopoeia, 30th ed, p173) [ChemIDplus]
Household ProductsInformation on 1 consumer products that contain Cystamine dihydrochloride in the following categories is provided:
General Manufacturing InformationEthanamine, 2,2'-dithiobis-, hydrochloride (1:2): ACTIVE
Anwendungen
VerwendenCystamine dihydrochloride acts as an anti-infective agent, which is used in the treatment of urinary tract infections. It is also used as a radiation-protective agent that interferes with sulfhydryl enzymes. Further, it serves as a heparin antagonist and sulfhydryl modifying reagent. In addition to this, it is used as an inhibitor of TGase.
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