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Phenylhydrazinhydrochlorid

Phenylhydrazine hydrochloride

HCID 60962
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Grundinformationen

CAS
27140-08-5
Standard-SMILES
Cl.NNc1ccccc1
InChIKey
JOVOSQBPPZZESK-UHFFFAOYSA-N
Summenformel
C6H8N2.ClH
Durchschnittliche Molmasse
144,6 g/mol
Monoisotopische Masse
144,045426

Überblick

Phenylhydrazine hydrochloride is a white to tan solid with a weak aromatic odor. (EPA, 1998)

Namen und Bezeichner

Bevorzugter Name
Phenylhydrazine hydrochloride
IUPAC
phenylhydrazine;hydrochloride
Lokaler Name
Phenylhydrazinhydrochlorid
Englischer Name
phenylhydrazine hydrochloride
Summenformel
C6H9ClN2
Molmasse
144.6

Namen und Synonyme

PHENYLHYDRAZINE HYDROCHLORIDE59-88-1Phenylhydrazinium chloridePhenylhydrazine-HClPhenylhydrazine monohydrochlorideHydrazine, phenyl-, monohydrochloridePhenylhydrazin hydrochloridHydrazine, phenyl-, hydrochlorideDTXSID3021148H7QFK49SVDHydrazine, phenyl-, hydrochloride (1:1)NSC-5710
Weitere Namen anzeigen
Phenylhydrazine/hydrochloric acid,(1:x)
DTXCID701148CHEBI:136540RefChem:173074200-444-7248-259-0PHENYLHYDRAZINE HCLPhenylhydrazine.HCl27140-08-5

Datenbank-Bezeichner

CAS
27140-08-5、59-88-1
PubChem CID
60962
DTXSID
DTXSID3021148
ChEMBL
CHEMBL3182475
ChEBI
CHEBI:136540
UNII
H7QFK49SVD
EC Number
200-444-7、248-259-0

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
38,1 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
1
Schwere Atome
9
Formalladung
0
Komplexität
57,5

Experimentelle und physikochemische Eigenschaften

Chemical Classes · 2 Einträge

Nitrogen Compounds -> Hydrazines

Flammable agents - 2nd degree

DensityGreater than 1 at 68 °F (EPA, 1998)
Boiling PointNot pertinent; it decomposes (EPA, 1998)
Melting Point469 to 475 °F (EPA, 1998)
Physical Description · 2 Einträge

Phenylhydrazine hydrochloride is a white to tan solid with a weak aromatic odor. (EPA, 1998)

White to tan solid with a mild aromatic odor; [CAMEO] White powder; [Alfa Aesar MSDS]

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: Hydrazine, phenyl-, hydrochloride (1:1)

Hazard Traits - Carcinogenicity

Hazard Traits - Carcinogenicity

Phenylhydrazinium chloride: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Other Safety InformationIMAP assessments - Phenylhydrazine and its monohydrochloride: Human health tier II assessment
Fire HazardsToxic and irritating hydrogen chloride and oxides of nitrogen may be produced in fire. May be corrosive to metals. Hazardous polymerization may not occur. (EPA, 1998)
Health Hazards · 1 Eintrag

This material is poisonous if swallowed or if fumes are inhaled. Dust is irritating to eyes, nose, and throat. Phenylhydrazine is a chronic poison. Phenylhydrazine is an industrial substance suspect of carcinogenic potential for humans. (EPA, 1998)

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationElectron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION).

Verwendung und Herstellung

UsesUsed to make dyes, antipyrine, and nitron (explosives stabilizer); as a reagent for sugars, aldehydes, and ketones; and as a therapeutic hemolytic; [Merck Index]
General Manufacturing InformationHydrazine, phenyl-, hydrochloride (1:1): ACTIVE

Zugehörige Reaktionen

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Hazards Summary · 1 Eintrag

Causes cyanosis, corrosion, and weight loss in dermal lethal-dose studies of rabbits; Causes methemoglobinemia, respiratory stimulation, and normocytic anemia in intraperitoneal lethal-dose studies of rats; [RTECS] Overexposure may cause skin sensitization, hemolytic anemia, dyspnea, cyanosis, jaundice, kidney injury, vascular thrombosis, and occupational cancer; [Merck Index] An irritant and chronic poison; Ingestion may cause jaundice, anorexia, nausea, vascular thrombosis, anemia, and liver injury; [CHRIS] A skin and strong eye irritant; May cause skin sensitization; Toxic by ingestion, inhalation, and skin absorption; Risk of irreversible adverse health effects; Suspected to cause genetic defects and cancer; [Alfa Aesar MSDS] See Phenylhydrazine.

Reactive GroupAzo, Diazo, Azido, Hydrazine, and Azide Compounds
Reactivity ProfilePHENYLHYDRAZINE HYDROCHLORIDE may be corrosive to metals (USCG, 1999).
Air and Water ReactionsForms corrosive acidic solutions.
Hazard Classes and Categories · 6 Einträge

Acute Tox. 3 (96.1%)

Carcinogenicity - category 1B

Acute toxicity - category 3

Self-reactive substances and mixtures - Type G

Flammable agents - 2nd degree

Carc. 1B

Lower Explosive Limit (LEL)Combustible. (EPA, 1998)
Upper Explosive Limit (UEL)Combustible. (EPA, 1998)

Sicherheit und Schutzausrüstung

Fire FightingWear goggles and self-contained breathing apparatus.
First AidWarning: Phenylhydrazine hydrochloride is highly irritating to eyes, nose, and throat. Caution is advised.
Nonfire Spill Response · 1 Eintrag

Avoid contact with solid and dust. Restrict access. Disperse and flush. (Non-Specific -- Phenylhydrazine) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Do not touch spilled material; stop leak if you can do it without risk.

Protective Action Criteria (PAC) · 3 Einträge

22 [mg/m3]

250 [mg/m3]

1500 [mg/m3]

Personal Protective Equipment (PPE) · 1 Eintrag

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

Toxikologische Informationen

Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.