D-Lactic Acid (HCID 61503)

Überblick

(R)-lactic acid is an optically active form of lactic acid having (R)-configuration. It has a role as an Escherichia coli metabolite and a human metabolite. It is a conjugate acid of a (R)-lactate. It is an enantiomer of a (S)-lactic acid.

Namen und Bezeichner

Bevorzugter Name: D-Lactic Acid
IUPAC: (2R)-2-hydroxypropanoic acid
Lokaler Name: (R)-Milchsure
Englischer Name: (R)-Lactate
Summenformel: C3H6O3
Molmasse: 90.08

Namen und Synonyme

D-Lactic acid10326-41-7(R)-2-Hydroxypropanoic acidD-(-)-Lactic acid(2R)-2-hydroxypropanoic acid(R)-Lactic acid(-)-Lactic acidPropanoic acid, 2-hydroxy-, (2R)-(R)-2-Hydroxypropionic acid(R)-(-)-Lactic acidD-MilchsaeureD-2-Hydroxypropanoic acid

Weitere Namen anzeigen

D-MILK ACID(r)-lactateD-（& # 8722D-LaCLic Acid(R)-lacticaciD(-)LACTIC ACID

Lactic acid, D-D-2-Hydroxypropionic acid(R)-alpha-Hydroxypropionic acidDTXSID00470303Q6M5SET7WDTXCID8027030CHEBI:42111RefChem:584137

Datenbank-Bezeichner

CAS: 10326-41-7
PubChem CID: 61503
DTXSID: DTXSID0047030
ChEMBL: CHEMBL358850
ChEBI: CHEBI:42111
UNII: 3Q6M5SET7W
EC Number: 233-713-2
Nikkaji: J9.141C

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -0,7
Polarare Oberfläche (TPSA): 57,5 Å²
H-Brücken-Donoren: 2
H-Brücken-Akzeptoren: 3
Frei drehbare Bindungen: 1
Schwere Atome: 6
Formalladung: 0
Komplexität: 59,1

Experimentelle und physikochemische Eigenschaften

SpringerMaterials PropertiesCoriolis coupling

Melting Point52.8 °C

Physical DescriptionSolid

Dissociation Constants · 2 Einträge

3.861

3.83

Physikochemische Eigenschaften

Schmelzpunkt: 52.8 ° · 52.8°
Siedepunkt: 227.6 · 227.6±0.0 °C(Predicted)
Dichte: 1.276 · 1.276±0.06 g/cm3(Predicted)
Dampfdruck: 3.8 Pa · 3.8Pa at 25℃
Brechungsindex: 1.428 to · 1.4280 to 1.4320
FEMA: 2611 · 2611 | LACTIC ACID
storage temp.: -20 °C · -20°C
Löslichkeit: 2 O: · H2O: 0.1 g/mL, clear, colorless
Aggregatzustand: Low Melting Solid
pka: 3.83 · pK = 3.83(at 25℃)
Farbe: White to Off-white
Geruch (Odor): odorless acidic
Wasserlöslichkeit: Soluble in water (50mg/ml)
Merck: 14 · 14,5335
JECFA Number: 930 · 930
BRN: 1720252 · 1720252
Stabilität: Hygroscopic
InChI: 1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m1/s1
InChIKey: JVTAAEKCZFNVCJ-UWTATZPHSA-N
SMILES: C[C@@H](O)C(O)=O
LogP: -0.54 at · -0.54 at 20℃
CAS Datenbank: 10326 · 10326-41-7(CAS DataBase Reference)
EPA chemische Informationen: 2 · Propanoic acid, 2-hydroxy-, (2R)- (10326-41-7)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H314 (10.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P332+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 48 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Propanoic acid, 2-hydroxy-, (2R)-

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 22-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/12317

Propanoic acid, 2-hydroxy-, (2R)-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Lactic acid isomers

Hazard Classes and Categories · 2 Einträge

Skin Corr. 1C (10.4%)

Skin corrosion/irritation - Category 1

Toxikologische Informationen

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).

Sicherheitsdaten

F: 3-10
wgk: 3
tsca: TSCA listed
ridadr: UN 3265 8/PG III
hs_code: 2918110000
risk_code: 38-41
hazard_code: Xi
safety_code: 26-39
hazard_class: 8
packing_group: III
Speicherklasse: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Eye Dam. 1Skin Corr. 1C

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsBladder

Cellular LocationsExtracellular

Metabolite PathwaysLeigh Syndrome

Verwendung und Herstellung

UsesThis is an endogenously produced metabolite found in the human body. It is used in metabolic reactions, catabolic reactions or waste generation.

General Manufacturing InformationPropanoic acid, 2-hydroxy-, (2R)-: ACTIVE

Anwendungen · 1 Eintrag

VerwendenD-(-)-Lactic acid is a useful biochemical for proteomics research. It is also used in the production of chiral drug and in the chemical synthesis. Lactic acid is used as a reagent in organic synthesis (in the manufacture of adhesives). It is used in the leather, textile, and tanning industries. It may be used as a plasticizer, a catalyst, or an acidifying agent. Lactic acid has even been used as a flavoring agent in the manufacture of tobacco products.