DL-Serin

DL-Serine

HCID 617CAS 302-84-1
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Grundinformationen

Standard-SMILES
NC(CO)C(=O)O
InChIKey
MTCFGRXMJLQNBG-UHFFFAOYSA-N
Summenformel
C3H7NO3
Durchschnittliche Molmasse
105,09 g/mol
Monoisotopische Masse
105,04259309

Namen und Bezeichner

Bevorzugter Name
DL-Serine
IUPAC
2-amino-3-hydroxypropanoic acid
Lokaler Name
DL-Serin
Englischer Name
DL-Serine
Summenformel
C3H7NO3
Molmasse
105.09

Namen und Synonyme

DL-Serine302-84-1Serine, DL-00PAR1C66FNSC-9960DTXSID70859325NSC99602-azaniumyl-3-hydroxypropanoateSerine DL-RefChem:1083916DTXCID20202802206-130-6
Weitere Namen anzeigen
SERINEserinDL-SER2-AMINO-3-HYDROXY-PROPIONIC ACIDDL-SerinDL-Ser-OHDL-SERINE,FCC
2-Amino-3-hydroxypropanoic acidSerine DL-formH-DL-Ser-OHSERINE, (L)d,l-serineL-Serine-2-13c-15N2-amino-3-hydroxy-propanoic acidDL-2-Amino-3-hydroxypropionic Acid

Datenbank-Bezeichner

CAS
302-84-1、312-84-5、56-45-1
PubChem CID
617
DTXSID
DTXSID70859325
ChEBI
CHEBI:17822
UNII
00PAR1C66F
EC Number
206-130-6
Nikkaji
J1.277G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-3,1
Polarare Oberfläche (TPSA)
83,6 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
2
Schwere Atome
7

Experimentelle und physikochemische Eigenschaften

Physical DescriptionSolid; [Merck Index] Beige crystalline solid; [Sigma-Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
240 °C · 240 °C (dec.) (lit.)
Siedepunkt
197.09 °C · 197.09°C (rough estimate)
Dichte
1.53 · 1.53
Brechungsindex
1.4368 · 1.4368 (estimate)
storage temp.
30 °C · Store below +30°C.
Löslichkeit
2 O: · H2O: soluble

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 99.6% (261 of 262) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 261 of 262 companies (only 0.4% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 262 reports by companies from 2 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 261 of 262 reports by companies.；There is 1 notification provided by 1 of 262 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: DL-Serine

Regulation (EC) No 1831/2003 (amended)

Status: Active Update: 12-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21820

Serine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - DL-Serine: Environment tier I assessment；Evaluation - Chemicals that are unlikely to require further regulation to manage risks to human health
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See L-Serine.
Hazard Classes and CategoriesNot Classified

Regulatorische Informationen

Regulatory Information · 4 Einträge

Chemical: DL-Serine

Regulation (EC) No 1831/2003 (amended)

Status: Active Update: 12-08-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21820

Serine: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29225000
RTECS-Nr.
VT8100000
risk_code
36/37/38
hazard_code
Xi

Chemie und Industrie

Verwendung und Herstellung

UsesA non-essential amino acid; [Merck Index]
General Manufacturing InformationSerine: ACTIVE
Anwendungen · 2 Einträge

BeschreibungDL-Serine is a kind of neutral aliphatic amino acids containing hydroxyl groups with polarity but being uncharged, and belongs to nonessential amino acids for human body. It has a high content in sericin silk protein and fibroin protein. It can be formed from the methyl transfer reaction of glycine. It can also be converted to pyruvate or hydroxy pyruvate through deamination. It is also an important raw material for in vivo synthesis of choline and cysteine.

VerwendenDL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer’s treatment.

Darstellung

synthetischeDL-serine is obtained by complexing glycine under the catalysis of copper ions and then combining with formaldehyde under alkaline conditions, followed by acidification, ion exchange, and crystallization in ethanol.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
普洛药业股份有限公司/浙江横店普洛进出口有限公司+86-0571-87635730 +86-13588737631
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.

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