HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 62005Erstellt: 26. Oktober 2026
Tobramycinsulfat
Tobramycin sulfate · TOBRAMYCIN SULPHATE · obracine · tenemicin · TOBRAMYCIN SLIPHATE · TobraMycin Sulfate API · 1-epitobramycinsulfate · TOBRAMYCIN SULFATE SALT
https://huagongshe.com/de/chemical/62005
Identifikatoren & physikalische Daten
| CAS No. | 49842-07-1 |
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| Summenformel | C18H39N5O13S |
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| Durchschnittliche Molmasse | 565,6 g/mol |
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| SMILES | NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](N)C[C@@H]1O.O=S(=O)(O)O |
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| InChIKey | ZEUUPKVZFKBXPW-TWDWGCDDSA-N |
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| PubChem CID | 62005 |
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| ChEMBL | CHEMBL1200780 |
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| Lokaler Name | Tobramycinsulfat |
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Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 351 |
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| H-Brücken-Donoren | 12 |
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| H-Brücken-Akzeptoren | 18 |
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| Frei drehbare Bindungen | 6 |
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| Schwere Atome | 37 |
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| Formalladung | 0 |
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| Komplexität | 690 |
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| Lagerbedingungen | 2-8°C |
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| Löslichkeit | Methanol (Slightly), Water (Sparingly)Soluble in water (50 mg/ml). |
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| Aggregatzustand | Powder |
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| Farbe | White to off-white |
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| Stabilität | Hygroscopic |
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| InChIKey | ZEUUPKVZFKBXPW-SYOBZNKXNA-N |
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| SMILES | OS(O)(=O)=O.NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O |
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| CAS Datenbank | 49842-07-1 |
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| EPA chemische Informationen | Tobramycin sulfate (49842-07-1) |
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Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
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| Zollcode | 2941900000 |
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| R-Sätze (R) | 61-20/21/22 |
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| Gefahrensymbole | T |
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| Sicherheitshinweise (S) | 53-22-36/37/39-45 |
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| Lagerklasse | 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects |
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| Gefahrenklasse | Acute Tox. 4 DermalAcute Tox. 4 InhalationRepr. 1B |
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Anwendungen & Verwendung
Verwenden
Tobramycin sulfate is used as an antibiotic which is used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas. It is used to inhibit bacterial protein synthesis at the level of 30S (16S rRNA) and 70S ribosomal complex assembly. It is used to treat pseudomonas aeruginosa lung infections and is used in combination with other antibiotics to treat urinary tract infections, gynecologic infections, peritonitis, endocarditis, pneumonia, sepsis, respiratory infections, osteomyelitis and other soft-tissue infections. It is a potential therapy for sinus infections1. Product T1783 has been used to study antibiotic resistance2.