Dimethyl Sulfone (HCID 6213)

Überblick

Sulfonyldimethane is a sulfone.

Namen und Bezeichner

Bevorzugter Name: Dimethyl Sulfone
IUPAC: methylsulfonylmethane
Lokaler Name: Dimethylsulfon
Englischer Name: Dimethyl sulfone
Summenformel: C2H6O2S
Molmasse: 94.13

Namen und Synonyme

Dimethyl sulfoneMethyl sulfone67-71-0MethylsulfonylmethaneDimethyl sulphoneSulfonylbismethaneMethane, sulfonylbis-sulfonyldimethaneMETHYL SULFONYL METHANEMethylsulfonyl methaneDTXSID40439379H4PO4Z4FT

Weitere Namen anzeigen

MSMDMSO2(CH3)2SO2DimethylsulfonMethylSulfonylMethane(Msm)Dimethyl sulfone solutionMETHYLSULPHONE

NSC-63345CHEBI:9349DTXCID2023937NSC63345methyl sulfonmethaneMSM2000 PremiumSUL VITAL HOTRefChem:134278

Datenbank-Bezeichner

CAS: 67-71-0
PubChem CID: 6213
DTXSID: DTXSID4043937
ChEMBL: CHEMBL25028
ChEBI: CHEBI:9349
UNII: 9H4PO4Z4FT
EC Number: 200-665-9
Nikkaji: J1.412E

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -0,4
Polarare Oberfläche (TPSA): 42,5 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 0
Schwere Atome: 5
Formalladung: 0
Komplexität: 85,3

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Classes -> Sulfur Compounds

DrugsPharmaceuticals -> Listed in ZINC15

CosmeticsSolvent

SpringerMaterials PropertiesSchoenflies notation

LogP-1.41

Density1.1700 @ 10°C

Physikochemische Eigenschaften

Schmelzpunkt: 107 · 107-109 °C (lit.)
Siedepunkt: 238 °C · 238 °C (lit.)
Dichte: 1 · 1,16 g/cm3
Brechungsindex: 1.4226 · 1.4226
Flammpunkt: 290 °F · 290 °F
storage temp.: 30 °C · Store below +30°C.
Löslichkeit: 150 g/l · 150g/l
pka: 28 · 28(at 25℃)
Aggregatzustand: Crystals or Crystalline Powder
Farbe: White
Geruch (Odor): 1 % · at 1.00%. sulfurous burnt
Wasserlöslichkeit: 150 g/L · 150 g/L (20 ºC)
Spezifische Wärmekapazität: 1.06 J/ · Cp(gas): 1.06 J/(g·K), at 25℃
Merck: 14 · 14,3258
BRN: 1737717 · 1737717
Henry's Law Constant: 5 · 5.0×10-3 mol/(m3Pa) at 25℃, Mackay et al. (2006)
Stabilität: Stable. Combustible. Incompatible with strong oxidizing agents.
Kosmetik-Inhaltsstoffe Funktionen: SOLVENTVISCOSITY CONTROLLING
InChI: 1S/C2H6O2S/c1-5(2,3)4/h1-2H3
InChIKey: HHVIBTZHLRERCL-UHFFFAOYSA-N
SMILES: CS(C)(=O)=O
LogP: -1.074 · -1.074 (est)
CAS Datenbank: 67 · 67-71-0(CAS DataBase Reference)
NIST chemische Informationen: Dimethyl sulfone(67-71-0)
EPA chemische Informationen: Dimethyl sulfone (67-71-0)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 96.1% (122 of 127) of all reports.

Not Classified

Aggregated GHS information provided per 127 reports by companies from 5 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Methane, sulfonylbis-

Methane, 1,1'-sulfonylbis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methane, 1,1'-sulfonylbis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 04-08-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/17580

Dimethyl sulfone: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryNo evidence of teratogenicity in rats; [REPROTOX] Not a skin irritant; May cause eye irritation; [Alfa Aesar MSDS] See Dimethyl sulfoxide. See Dipropyl sulfone.

Hazard Classes and CategoriesNot Classified

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 3 Einträge

15 [mg/m3]

170 [mg/m3]

990 [mg/m3]

Toxikologische Informationen

Effects During Pregnancy and Lactation◉ Summary of Use during Lactation

Sicherheitsdaten

wgk: 1
tsca: TSCA listed
hs_code: 29309070
RTECS-Nr.: PB2785000
Toxizität: LD50 orally in Rabbit: 17000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
safety_code: 22-24/25
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationSubstances that reduce or suppress INFLAMMATION.

Tissue LocationsBrain

Cellular LocationsCytoplasm

Verwendung und Herstellung

UsesOccurs in some plants and in the adrenal cortex of cattle; Used as a solvent; [Merck Index] A metabolite of dimethyl sulfoxide that naturally occurs in many foods; Marketed as a dietary supplement for promotion of joint health; [REPROTOX]

U.S. Production2023: 67,460 lb

Consumer UsesSoil amendments (fertilizers)

Use ClassificationCosmetics -> Solvent

General Manufacturing InformationMethane, 1,1'-sulfonylbis-: ACTIVE

Anwendungen

VerwendenDimethyl sulfone is a high tempereture solvent for many inorganic and organic substances,it is used as antiinflammatory, antiproliferative, antiparasitic.