Tetraethylammonium Bromide (HCID 6285)

Überblick

See also: Tetraethylammonium (has active moiety).

Namen und Bezeichner

Bevorzugter Name: Tetraethylammonium Bromide
IUPAC: tetraethylazanium bromide
Lokaler Name: Tetrylammoniumbromid
Englischer Name: Tetraethylammonium bromide
Summenformel: C8H20BrN
Molmasse: 210.16

Namen und Synonyme

TETRAETHYLAMMONIUM BROMIDE71-91-0TEABSympatektomanEtambroEthylonBromethylTetraniumBeparonEtamonEtylonTeamon

Weitere Namen anzeigen

tetraethylazanium bromideTetra ethyl ammonium bromide SolidEthanaminium, N,N,N-triethyl-, bromide (1:1)tmd10

Tetrylammonium bromideTEA bromideTetraethyl ammonium bromideEthanaminium, N,N,N-triethyl-, bromideBromuro de tetrilamonioBromure de tetrylammoniumTMD 10Bromure de tetraethylammonium

Datenbank-Bezeichner

CAS: 71-91-0
PubChem CID: 6285
DTXSID: DTXSID9044457
ChEMBL: CHEMBL324254
UNII: 0435621Z3N
EC Number: 200-769-4

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 0 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 1
Frei drehbare Bindungen: 4
Schwere Atome: 10
Formalladung: 0
Komplexität: 47,5

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Quaternary Amines

Density1.39 @ 20°C

Vapor Pressure0.00000079 [mmHg]

Physical Description · 2 Einträge

Liquid

Deliquescent solid; [Merck Index] Colorless crystalline solid; Highly hygroscopic; [Sigma-Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt: 285 °C · 285 °C (dec.)(lit.)
Siedepunkt: 310 °C/979.1 · >310 °C/979.1 hPa
Dichte: 1 · 1,397 g/cm3
Dampfdichte: 5.3 · 5.3 (vs air)
Dampfdruck: 1 hPa · <1 hPa
Brechungsindex: 1 · 1,442-1,444
storage temp.: 30 °C · Store below +30°C.
Löslichkeit: 0.1 g/mL · acetonitrile: 0.1 g/mL warm, clear, colorless
Aggregatzustand: Liquid
Farbe: White to cream
Geruch (Odor): Odorless
PH: 6.5 · 6.5 (100g/l, H2O, 20℃)
Wasserlöslichkeit: 2795 g/L · 2795 g/L (25 º C)
Merck: 14 · 14,9199
BRN: 3563430 · 3563430
Stabilität: Stable. Incompatible with strong oxidizing agents.
InChI: 1S/C8H20N.BrH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1
InChIKey: HWCKGOZZJDHMNC-UHFFFAOYSA-M
SMILES: [Br-].CC[N+](CC)(CC)CC
CAS Datenbank: 71 · 71-91-0(CAS DataBase Reference)
NIST chemische Informationen: Tetraethylammonium bromide(71-91-0)
EPA chemische Informationen: Ethanaminium, N,N,N-triethyl-, bromide (71-91-0)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 1.6% (5 of 317) of reports.

Warning

H302 (18.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 317 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: Ethanaminium, N,N,N-triethyl-, bromide

Ethanaminium, N,N,N-triethyl-, bromide (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanaminium, N,N,N-triethyl-, bromide (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/19226

Tetraethylammonium bromide: HSNO Approval: HSR006306 Approved with controls

Other Safety InformationIMAP assessments - Tetraethylammonium salts: Human health tier II assessment

Hazards Summary · 1 Eintrag

Causes mydriasis, tremor, and changes in motor activity in acute intraperitoneal studies of mice; Causes ganglion blockage and lowered blood pressure in acute intravenous studies of cats; [RTECS] A skin and strong eye irritant; Targets the heart and CNS; [Sigma-Aldrich MSDS]

Hazard Classes and Categories · 2 Einträge

Acute Tox. 4 (18.3%)

Eye irritation - category 2B

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 3 Einträge

8.4 [mg/m3]

92 [mg/m3]

550 [mg/m3]

Sicherheitsdaten

F: 3
wgk: 3
tsca: TSCA listed
hs_code: 29239000
RTECS-Nr.: BS5950000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-37/39
Speicherklasse: 11 - Combustible Solids
Hazard Classifications: Aquatic Chronic 3

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationA class of drugs that act by inhibition of potassium efflux through cell membranes. Blockade of potassium channels prolongs the duration of ACTION POTENTIALS. They are used as ANTI-ARRHYTHMIA AGENTS and VASODILATOR AGENTS.

Verwendung und Herstellung

UsesA ganglion blocking agent; [Merck Index]

U.S. Production2023: 1,000,000 - <5,000,000 lb

Industry UsesIntermediate

General Manufacturing Information · 2 Einträge

All Other Basic Organic Chemical Manufacturing

Ethanaminium, N,N,N-triethyl-, bromide (1:1): ACTIVE

Anwendungen

VerwendenTetraethylammonium Bromide, can be used as a source of tetraethylammonium ions for various pharmaceutical studies. It has also the ability to block K+ channels in various tissues.