1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol

Dimethyl Isosorbide

HCID 62990CAS 5306-85-4
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
CO[C@H]1CO[C@H]2[C@@H]1OC[C@H]2OC
InChIKey
MEJYDZQQVZJMPP-ULAWRXDQSA-N
Summenformel
C8H14O4
Durchschnittliche Molmasse
174,19 g/mol
Monoisotopische Masse
174,08920893

Namen und Bezeichner

Bevorzugter Name
Dimethyl Isosorbide
IUPAC
(3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan
Lokaler Name
1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol
Englischer Name
Isosorbide dimethyl ether
Summenformel
C8H14O4
Molmasse
174.2

Namen und Synonyme

Isosorbide dimethyl ether5306-85-4Dimethyl isosorbide2,5-Dimethylisosorbide1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitolSA6A6V432SNSC-40727NSC-44695D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-DTXSID201019399RefChem:1342482,5-O-dimethylisosorbide
Weitere Namen anzeigen
DIMETHYL ISOBORBIDE(3R,3aR,6S,6aR)O,O-DIMETHYLISOSORBIDEDiMethyl Isosorbide(DMI)SOSORBIDE DIMETHYL ETHERlsosorbide dimethyl ether
DTXCID201477371226-159-8Arlasolve DMI(3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furanMFCD00064828(3S,3aR,6R,6aR)-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan2,5-Di-O-methyl-1,4:3,6-dianhydro-D-glucitol(3R,3aR,6S,6aR)-3,6-dimethoxy-hexahydrofuro[3,2-b]furan

Datenbank-Bezeichner

CAS
5306-85-4
PubChem CID
62990
DTXSID
DTXSID201019399
UNII
SA6A6V432S
EC Number
226-159-8
Nikkaji
J208.650F

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-0,6
Polarare Oberfläche (TPSA)
36,9 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
2
Schwere Atome
12

Experimentelle und physikochemische Eigenschaften

CosmeticsSolvent
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Physical DescriptionLiquid

Physikochemische Eigenschaften

Schmelzpunkt
-70 °C · -70°C
Siedepunkt
93 · 93-95 °C0.1 mm Hg(lit.)
Dichte
1.15 g/mL · 1.15 g/mL at 25 °C(lit.)
Dampfdruck
12.54 Pa · 12.54Pa at 20℃
Brechungsindex
20 · n20/D 1.461(lit.)
Flammpunkt
227 °F · 227 °F

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 99.6% (225 of 226) of all reports.

Not Classified

Aggregated GHS information provided per 226 reports by companies from 2 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 5 Einträge

Chemical: D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-

D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: Active Update: 08-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/21446

D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesNot Classified

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29092000
safety_code
23-24/25
Speicherklasse
10 - Combustible liquids

Chemie und Industrie

Verwendung und Herstellung

U.S. Production2023: 305,816 lb
Consumer UsesSurfactant (surface active agent)
Industry UsesSolvent
Household ProductsInformation on 1 consumer products that contain Dimethyl Isosorbide in the following categories is provided:
Use ClassificationCosmetics -> Solvent
General Manufacturing Information · 2 Einträge

Pharmaceutical and Medicine Manufacturing

D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-: ACTIVE

Anwendungen · 1 Eintrag

VerwendenIsosorbide dimethyl ether (DMI), a sustainable solvent, is widely used in various cosmetic and pharmaceutical formulations.General applications:DMI can be used as an alternative green solvent for epoxidation of cyclooctene, Baylis–Hillman reaction of isomaltulose-derived aldehydes with α,β-unsaturated ketones and also in solid-phase synthesis.It can be used as a coalescent for water-borne paints, where it acts as a co-solvent during the water loss phase and as a coalescing agent during the film formation.

Darstellung · 1 Eintrag

synthetischeIsosorbide dimethyl ether is synthesized from isosorbide by methylation.Isosorbide dimethyl ether is obtained from stock like D-sorbitol, which is mainly derived from the hydrogenation of D-glucose.Isosorbide dimethyl has a low level of toxicity and is referred to as a green solvent due to its production from renewable/raw material.The boiling point of this solvent is high.lt is used as a substitute to dimethyl sulfoxide,and dimethylformamide-like solvents.

Vor- und nachgelagerte Produkte

Nachgelagerte Produkte

Anbieter50 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]

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