Methylprednisolone aceponate

HCID 63019CAS 86401-95-8

Daten werden ergänzt – meist innerhalb einer Minute fertig

Grundinformationen

Standard-SMILES
CCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C
InChIKey
DALKLAYLIPSCQL-YPYQNWSCSA-N
Summenformel
C27H36O7
Durchschnittliche Molmasse
472,578 g/mol
Monoisotopische Masse
472,24610349

Namen und Bezeichner

Bevorzugter Name
Methylprednisolone aceponate
IUPAC
21-(Acetyloxy)-11-hydroxy-6alpha-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
Englischer Name
Methylprednisolone aceponate
Summenformel
C27H36O7
Molmasse
472.57

Namen und Synonyme

AdvantanSH-440ZK-91588ZK-91-588AceponateZK-91588:SH-440Prednisolone Impurity 21METHYLPREDNISOLONE ACEPONATEMethilprednisolone aceponateMethylprednisolone Impurity 55

Datenbank-Bezeichner

CAS
86401-95-8
PubChem CID
63019
DTXSID
DTXSID2023301
ChEMBL
CHEMBL1697782
ChEBI
CHEBI:135762
UNII
ET54W9J4U2
EC Number
658-084-5、687-724-6
Nikkaji
J25.810E

Eigenschaften

Physikochemische Eigenschaften

Schmelzpunkt
105 · 105 - 108°C
Siedepunkt
595.8 · 595.8±50.0 °C(Predicted)
Dichte
1.23 · 1.23±0.1 g/cm3(Predicted)
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Ethyl Acetate(Slightly)
pka
14.05 · 14.05±0.70(Predicted)

Sicherheit und Regulatorisches

Sicherheitsdaten

Alarmwort
Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H361

Chemie und Industrie

Anwendungen · 2 Einträge

BeschreibungMethylprednisolone aceponate (MPA) is a new potent topical corticosteroid. Chemically, it is a corticosteroid diester that penetrates the skin rapidly. It is rapidly metabolised and then conjugated, so although potent, it does not appear to cause serious local or systemic side effects. Clinical trials have shown that once daily use is sufficient to control most eczematous conditions and is also appropriate and effective in atopic dermatitis. MPA is effective in the treatment of facial and scalp eczema and sunburn and has shown promising results in the treatment of psoriasis. MPA is also suitable for use in children and infants. MPA is available in a wide range of formulations (0.1%) including creams, ointments, fat ointments, lotions and solutions depending on the patient's individual condition.

VerwendenMethylprednisolone aceponate used in treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus.

Anbieter50 Anbieter

上海策嵘生物科技有限公司[email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
艾吉析科技(上海)有限公司17717235263 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]

Zugehörige Reaktionen

2

Verknüpfte Notizen

Wird geladen…