HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Amlodipine Maleate
AMLODIPINE MALEATE · Amlodipine IH Impurity A · Amlodipine maleate USP/EP/BP · Amlodipine maleate - Bio-X ? · AMLODIPINE MALEATE MM STANDARD · Amlodipine maleate (crystalline) · Amlodipine maleate, 10 mM in DMSO · AmlodipineMaleateC20H25C1N205.C4H404
Identifikatoren & physikalische Daten
| CAS No. | 88150-47-4 |
|---|---|
| Summenformel | C24H29ClN2O9 |
| Durchschnittliche Molmasse | 524,9 g/mol |
| Monoisotopische Masse | 524,15615819 g/mol |
| SMILES | CCOC(=O)C1=C(COCCN)NC(C)=C(C(=O)OC)C1c1ccccc1Cl.O=C(O)/C=C\C(=O)O |
| InChIKey | TZNOWAJJWCGILX-BTJKTKAUSA-N |
| PubChem CID | 6435922 |
| ChEMBL | CHEMBL1200984 |
| EC No. | 629-849-0 |
| DTXSID | DTXSID601027708 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 174 |
|---|---|
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 11 |
| Frei drehbare Bindungen | 12 |
| Schwere Atome | 36 |
| Formalladung | 0 |
| Komplexität | 765 |
| Human Drugs | FDA approved drugs -> Active ingredient |
| Schmelzpunkt | 178-179° |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| Farbe | Off-White to Pale Yellow |
| Stabilität | Light Sensitive |
| InChIKey | TZNOWAJJWCGILX-BTJKTKAUSA-N |
| SMILES | C1(C2=CC=CC=C2Cl)C(=C(NC(COCCN)=C1C(=O)OCC)C)C(=O)OC.C(/C(=O)O)=C/C(=O)O |
| CAS Datenbank | 88150-47-4(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (40%): Toxic if swallowed [Danger Acute toxicity, oral]P203, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P318, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 3 (40%) |
| Alarmwort | Warnung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
Anti-anginal; antihypertensive.