Cephalosporin C

HCID 65536CAS 11111-12-9

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Grundinformationen

Standard-SMILES: CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CCC[C@@H](N)C(=O)O)[C@H]2SC1
InChIKey: HOKIDJSKDBPKTQ-GLXFQSAKSA-N
Summenformel: C16H21N3O8S
Durchschnittliche Molmasse: 415,4 g/mol
Monoisotopische Masse: 415,10493563

Überblick

Cephalosporin C is a cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N6-L-lysino group at position 7. It has a role as a fungal metabolite. It is functionally related to a cephalosporanic acid. It is a conjugate acid of a cephalosporin C(1-).

Namen und Bezeichner

Bevorzugter Name: Cephalosporin C
IUPAC: (6R,7R)-3-(acetyloxymethyl)-7-[[(5R)-5-amino-5-carboxypentanoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Namen und Synonyme

cephalosporin C61-24-57-(5-Amino-5-carboxyvaleramido)cephalosporanic acid3XIY7HJT5LCHEBI:15776DTXSID90960427NSC-757790(6R,7R)-3-(acetyloxymethyl)-7-[[(5R)-5-amino-5-carboxypentanoyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(6R,7R)-3-[(acetyloxy)methyl]-7-{[(5R)-5-amino-5-carboxypentanoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid(6R,7R)-3-((acetyloxy)methyl)-7-(((5R)-5-amino-5-carboxypentanoyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid(6R,7R)-3-(acetyloxymethyl)-7-(((5R)-5-amino-5-carboxypentanoyl)amino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acidRefChem:918232

Weitere Namen anzeigen

DTXCID2013882835-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-8-oxo-, (6R-(6 alpha,7 beta(R*)))-200-501-6(6R,7R)-3-(Acetoxymethyl)-7-((R)-5-amino-5-carboxypentanamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-((acetyloxy)methyl)-7-((5-amino-5-carboxy-1-oxopentyl)amino)-8-oxo-, (6R-(6alpha,7beta(R*)))-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(5-amino-5-carboxyvaleramido)-3-(hydroxymethyl)-8-oxo-, acetate (ester)EINECS 200-501-6UNII-3XIY7HJT5L

Datenbank-Bezeichner

CAS: 11111-12-9、39879-21-5、59143-60-1、61-24-5
PubChem CID: 65536
DTXSID: DTXSID90960427
ChEMBL: CHEMBL482858
ChEBI: CHEBI:15776
UNII: 3XIY7HJT5L
EC Number: 200-501-6、254-669-0、261-624-9
Nikkaji: J4.815A

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -4,4
Polarare Oberfläche (TPSA): 202 Å²
H-Brücken-Donoren: 4
H-Brücken-Akzeptoren: 10
Frei drehbare Bindungen: 10
Schwere Atome: 28
Formalladung: 0
Komplexität: 737

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Listed in ZINC15

Human DrugsPharmaceuticals

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Warning

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.

Warning

H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

Gefahrenhinweise

Regulatory InformationCephalosporin: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and Categories · 2 Einträge

Skin Sens. 1 (100%)

Repr. 2 (100%)