4-Morpholinopropansulfonsäure
Mops
Grundinformationen
- CAS
1132-61-2- Standard-SMILES
O=S(=O)(O)CCCN1CCOCC1- InChIKey
DVLFYONBTKHTER-UHFFFAOYSA-N- Summenformel
- C7H15NO4S
- Durchschnittliche Molmasse
- 209,27 g/mol
- Monoisotopische Masse
- 209,07217913
Überblick
3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 C. It is an organosulfonic acid, a member of morpholines and a MOPS. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.
Namen und Bezeichner
- Bevorzugter Name
- Mops
- IUPAC
- 3-morpholin-4-ylpropane-1-sulfonic acid
- Lokaler Name
- 4-Morpholinopropansulfonsäure
- Englischer Name
- MOPS
- Summenformel
- C7H15NO4S
- Molmasse
- 209.26
Namen und Synonyme
MOPS1132-61-23-Morpholinopropanesulfonic acid4-Morpholinepropanesulfonic acid3-(N-Morpholino)propanesulfonic acidMorpholinopropane sulfonic acid3-morpholin-4-ylpropane-1-sulfonic acidMorpholinopropanesulfonic acidDTXSID4044371273BP63NV3morpholine propanesulphonic acidDTXCID2024371
Weitere Namen anzeigen
MOPS FREE ACID4-propanesulfonyl morpholine3-Morpholinopropanesulfoinc Acid4-morpholinopropanesulphonic acid3-MORPHOLINOPROPANESULPHONIC ACID
CHEBI:441153-[N-Morpholino]propanesulfonic acidRefChem:926116CHEBI:39074214-478-53-Morpholinopropane-1-sulfonic acid3-(morpholin-4-yl)propane-1-sulfonic acid3[N-MORPHOLINO]PROPANE SULFONIC ACID
Datenbank-Bezeichner
- CAS
1132-61-2
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -3,1
- Polarare Oberfläche (TPSA)
- 75,2 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 227
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Uses -> Biological Buffers
DrugsPharmaceuticals -> Listed in ZINC15
Physical DescriptionWhite solid; [Merck Index] White odorless powder; [Caledon Laboratories MSDS]
Collision Cross Section142.7 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: APCI+; Dataset: TOXCAST; Source Identifier: DTXSID4044371]
Physikochemische Eigenschaften
- Schmelzpunkt
- 277 · 277-282 °C
- Dichte
- 1.3168 · 1.3168 (rough estimate)
- Dampfdruck
- 0 Pa · 0Pa at 25℃
- Brechungsindex
- 1.637 · 1.6370 (estimate)
- Flammpunkt
- 116 °C · 116 °C
- storage temp.
- room temp
- Löslichkeit
- 2 O: · H2O: 1 M at 20 °C, clear
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 45.9% (189 of 412) of reports.
Warning
H315 (53.4%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 412 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: 4-Morpholinepropanesulfonic acid
REACH registered substance: 4-morpholinopropanesulphonic acid (EC: 214-478-5)
MOPS: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Caledon Laboratories MSDS] See N-Ethylmorpholine.
Hazard Classes and CategoriesSkin Irrit. 2 (53.4%)
Sicherheitsdaten
- wgk
- 1
- tsca
- TSCA listed
- hs_code
- 2934999090
- RTECS-Nr.
- QE9104530
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Verwendung und Herstellung
UsesUsed as a biological buffer; [Merck Index] Used as a laboratory reagent; [Caledon Laboratories MSDS]
General Manufacturing Information4-Morpholinepropanesulfonic acid: ACTIVE
Anwendungen
VerwendenDue to its inert nature, 3-morpholinopropanesulfonic acid (MOPS) is widely used as a buffer in many biochemical studies. MOPS has been used as a cell culture additive component in lentiviral particle production, a buffering agent in microbial growth medium and nuclei extraction buffer, a component of Roswell Park Memorial Institute (RPMI) medium for diluting fungal inoculum, and a buffer in capillary-zone electrophoresis to test performance. It is also used for the dilution of proteins from algal samples.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Ergänzende Hinweise
DefinitionChEBI: 3-(N-morpholino)propanesulfonic acid is a Good's buffer substance, pKa = 7.2 at 20 ℃. It is a member of morpholines, a MOPS and an organosulfonic acid. It is a conjugate acid of a 3-(N-morpholino)propanesulfonate. It is a tautomer of a 3-(N-morpholiniumyl)propanesulfonate.
Zugehörige Reaktionen
33
Notizen zur Verbindung
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