HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Benzyloxycarbonyl-L-asparaginsure
Z-ASP · CBZ-ASP-OH · Z-ASP-OH · CBZ-L-ASP · N-CBZ-L-ASPARTIC ACID · N-CARBOBENZOXY-L-ASPARTIC ACID · Z-L-ASP-OH · CBZ-L-Asp-OH
Identifikatoren & physikalische Daten
| CAS No. | 1152-61-0 |
|---|---|
| Summenformel | C12H13NO6 |
| Durchschnittliche Molmasse | 267,23 g/mol |
| Monoisotopische Masse | 267,07428713 g/mol |
| SMILES | O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)O |
| InChIKey | XYXYXSKSTZAEJW-UHFFFAOYSA-N |
| PubChem CID | 70855 |
| ChEMBL | CHEMBL1161935 |
| Lokaler Name | N-Benzyloxycarbonyl-L-asparaginsure |
Chemische & physikalische Eigenschaften
| XLogP | 0,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 113 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 19 |
| Formalladung | 0 |
| Komplexität | 337 |
| Schmelzpunkt | 117-119 °C (lit.) |
| Siedepunkt | 410.42°C (rough estimate) |
| Dichte | 1.3276 (rough estimate) |
| Brechungsindex | 9.5 ° (C=7, AcOH) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | almost transparency in Methanol |
| pKa (Säurekonstante) | 3.75±0.23(Predicted) |
| Aggregatzustand | Fine Crystalline Powder |
| Farbe | White |
| BRN | 2336722 |
| Hauptanwendungen | peptide synthesis |
| InChI | 1S/C12H13NO6/c14-10(15)6-9(11(16)17)13-12(18)19-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,18)(H,14,15)(H,16,17)/t9-/m0/s1 |
| InChIKey | XYXYXSKSTZAEJW-VIFPVBQESA-N |
| SMILES | OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(O)=O |
| CAS Datenbank | 1152-61-0(CAS DataBase Reference) |
| EPA chemische Informationen | N-Carbobenzyloxy-L-aspartic acid (1152-61-0) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29242990 |
| R-Sätze (R) | 36/37/38-20/21/22 |
| Gefahrensymbole | Xi,Xn |
| Sicherheitshinweise (S) | 26-36-37/39 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Dam. 1Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
N-Cbz-L-aspartic acid is an N-Cbz-protected form of L-Aspartic acid (A790024). L-Aspartic acid is a nonessential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system.