D-Tyrosine (HCID 71098)

Namen und Bezeichner

Bevorzugter Name: D-Tyrosine
IUPAC: (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid
Lokaler Name: D-Tyrosin
Englischer Name: D-Tyrosine
Summenformel: C9H11NO3
Molmasse: 181.19

Namen und Synonyme

D-tyrosine556-02-5(2R)-2-amino-3-(4-hydroxyphenyl)propanoic acidD-TyrD-Tyrosin(R)-TYROSINEWQ5G9JQ7GCCHEBI:28479(R)-3-(p-Hydroxyphenyl)alanineEINECS 209-112-6D-4-HYDROXYPHENYLALANINEDTXSID50883441

Weitere Namen anzeigen

D-Tyr-OHD-THREONINOLD(+)-TYROSINED-thyrosineTYROSINE, D-D-p-TyrosineD-Tyrosine98%

(R)-2-Amino-3-(p-hydroxyphenyl)propionic acid2-amino-3-(4-hydroxyphenyl)-propanoic acidRefChem:585118DTXCID601022972(2R)-2-azaniumyl-3-(4-hydroxyphenyl)propanoate209-112-6H-D-Tyr-OH(R)-2-amino-3-(4-hydroxyphenyl)propanoic acid

Datenbank-Bezeichner

CAS: 556-02-5
PubChem CID: 71098
DTXSID: DTXSID50883441
ChEMBL: CHEMBL1076637
ChEBI: CHEBI:28479
UNII: WQ5G9JQ7GC
EC Number: 209-112-6
Nikkaji: J9.196K

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -2,3
Polarare Oberfläche (TPSA): 83,6 Å²
H-Brücken-Donoren: 3
H-Brücken-Akzeptoren: 4
Frei drehbare Bindungen: 3
Schwere Atome: 13
Formalladung: 0
Komplexität: 176

Experimentelle und physikochemische Eigenschaften

Solubility453

Physikochemische Eigenschaften

Schmelzpunkt: 300 °C · >300 °C (lit.)
Siedepunkt: 314.29 °C · 314.29°C (rough estimate)
Dichte: 1.2375 · 1.2375 (rough estimate)
Brechungsindex: 11.2 ° · 11.2 ° (C=5, 1mol/L HCl)
storage temp.: Store at RT.
Löslichkeit: Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
pka: 2.25 · 2.25±0.10(Predicted)
Aggregatzustand: Crystals or Powder
Farbe: White to off-white
Wasserlöslichkeit: SOLUBLE
Merck: 14 · 14,9839
BRN: 2212157 · 2212157
Major Application: peptide synthesis
Kosmetik-Inhaltsstoffe Funktionen: FRAGRANCEHAIR CONDITIONINGANTISTATICSKIN CONDITIONING
InChI: 1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m1/s1
InChIKey: OUYCCCASQSFEME-UHFFFAOYSA-N
SMILES: N[C@H](Cc1ccc(O)cc1)C(O)=O
LogP: -0.418 · -0.418 (est)
CAS Datenbank: 556 · 556-02-5(CAS DataBase Reference)
EPA chemische Informationen: D-Tyrosine (556-02-5)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 82.4% (42 of 51) of all reports.

Warning

H315 (17.6%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (17.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (15.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 42 of 51 reports by companies.；There are 6 notifications provided by 9 of 51 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory InformationChemical: D-Tyrosine

Other Safety InformationIMAP assessments - D-Tyrosine: Environment tier I assessment；Evaluation - Chemicals that are unlikely to require further regulation to manage risks to human health

Hazard Classes and CategoriesSkin Irrit. 2 (17.6%)；Eye Irrit. 2 (17.6%)；STOT SE 3 (15.7%)

Regulatorische Informationen

Regulatory InformationChemical: D-Tyrosine

Sicherheitsdaten

wgk: 3
tsca: TSCA listed
hs_code: 29225000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-24/25
Speicherklasse: 13 - Non Combustible Solids

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationD-Tyrosine: INACTIVE

Anwendungen · 1 Eintrag

VerwendenD-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic po lypropylene surfaces.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Chloracetylchlorid DL-Tyrosin

Nachgelagerte Produkte

BOC-D-TYR(BZL)-OH H-3,5-DIBROMO-D-TYR-OH N,O-Di-BOC-D-tyrosine 3-Bromo-D-Tyrosine

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: D-tyrosine is an optically active form of tyrosine having D-configuration. It has a role as an Escherichia coli metabolite. It is a tyrosine and a D-alpha-amino acid. It is a conjugate base of a D-tyrosinium. It is a conjugate acid of a D-tyrosinate(1-). It is an enantiomer of a L-tyrosine. It is a tautomer of a D-tyrosine zwitterion.