(±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylendipivalathydrochlorid

Dipivefrin Hydrochloride

HCID 71486CAS 64019-93-8
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Grundinformationen

Standard-SMILES
CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1.Cl
InChIKey
VKFAUCPBMAGVRG-UHFFFAOYSA-N
Summenformel
C19H30ClNO5
Durchschnittliche Molmasse
387,9 g/mol
Monoisotopische Masse
387,1812508

Namen und Bezeichner

Bevorzugter Name
Dipivefrin Hydrochloride
IUPAC
[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochloride
Lokaler Name
(±)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylendipivalathydrochlorid
Englischer Name
Dipivefrin hydrochloride
Summenformel
C19H30ClNO5
Molmasse
387.8982

Namen und Synonyme

Dipivefrin hydrochloride64019-93-8Dipivefrin HCLDipivefrine hydrochlorideAKProDTXSID20454945QTH9UHV0K(1)-4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-phenylene dipivalate hydrochlorideCHEBI:4647DTXCID0025494(RS)-4-(1-HYDROXY-2-(METHYLAMINO)ETHYL)-O-PHENYLENE DIPIVALATE HYDROCHLORIDEAlcon
Weitere Namen anzeigen
ProgateDiopinePivalephrineDipivefri ImpurityD6-Dipivefrine HClhydrochloride,(+-)-estedipivefrinhydrochloridedipivefrinehydrochlorideDipifrin (hydrochloride)
RefChem:56498dipivefrin hydrochloride, (+-)-Propanoic Acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene Ester, Hydrochloride,(+-)-Dipivefrin (hydrochloride)dipivefrine HClDipivefrine (hydrochloride)[2-(2,2-dimethylpropanoyloxy)-4-[1-hydroxy-2-(methylamino)ethyl]phenyl] 2,2-dimethylpropanoate;hydrochlorideDipivefrine hydrochloride (JAN)

Datenbank-Bezeichner

CAS
64019-93-8
PubChem CID
71486
DTXSID
DTXSID2045494
ChEMBL
CHEMBL1200833
ChEBI
CHEBI:4647
UNII
5QTH9UHV0K
EC Number
264-609-5

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
84,9 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
6
Frei drehbare Bindungen
9
Schwere Atome
26

Physikochemische Eigenschaften

Schmelzpunkt
158 · 158-159°
storage temp.
-20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
Löslichkeit
Freely soluble in water, very soluble in methanol, freely soluble in ethanol (96 per cent) and in methylene chloride.
Aggregatzustand
Solid
pka
8.4 · 8.40(at 25℃)
Farbe
White to Off-White

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Gefahrenhinweise

Hazard Classes and CategoriesAcute Tox. 3 (100%)

Sicherheitsdaten

wgk
WGK 3
ridadr
UN 2811 6.1 / PGIII
hs_code
2922504500
Speicherklasse
6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications
Acute Tox. 3 Oral

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationDrugs that bind to and activate adrenergic receptors.

Anwendungen

VerwendenAdrenergic (ophthalmic)

Anbieter50 Anbieter

南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
广州佳途科技股份有限公司81960175 18933936954 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: The hydrochloride salt of dipivefrin. It is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.

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