α-D-Ribofuranose-5-(dihydrogenphosphat)-1-(trihydrogendiphosphat)

Phosphoribosyl Pyrophosphate

HCID 7339CAS 13270-65-0

Grundinformationen

Standard-SMILES
O=P(O)(O)OC[C@H]1O[C@H](OP(=O)(O)OP(=O)(O)O)[C@H](O)[C@@H]1O
InChIKey
PQGCEDQWHSBAJP-TXICZTDVSA-N
Summenformel
C5H13O14P3
Durchschnittliche Molmasse
390,07 g/mol
Monoisotopische Masse
389,95181499

Überblick

5-O-phosphono-alpha-D-ribofuranosyl diphosphate is a derivative of alpha-D-ribose having a phosphate group at the 5-position and a diphosphate at the 1-position. It has a role as a mouse metabolite, a plant metabolite, an Escherichia coli metabolite and a human metabolite. It is functionally related to an alpha-D-ribose. It is a conjugate acid of a 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-).

Namen und Bezeichner

Bevorzugter Name
Phosphoribosyl Pyrophosphate
IUPAC
[(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl] phosphono hydrogen phosphate
Lokaler Name
α-D-Ribofuranose-5-(dihydrogenphosphat)-1-(trihydrogendiphosphat)
Englischer Name
alpha-D-ribofuranose 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate)
Summenformel
C5H13O14P3
Molmasse
390.069603

Namen und Synonyme

PHOSPHORIBOSYL PYROPHOSPHATE7540-64-9W5555R4ERG5-phosphoribosyl-1-pyrophosphateDTXSID40895038alpha-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate)(((2R,3S,4R,5R)-3,4-DIHYDROXY-5-((HYDROXY(PHOSPHONOOXY)PHOSPHORYL)OXY)OXOLAN-2-YL)METHOXY)PHOSPHONIC ACID{[(2R,3S,4R,5R)-3,4-dihydroxy-5-{[hydroxy(phosphonooxy)phosphoryl]oxy}oxolan-2-yl]methoxy}phosphonic acid(((((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonooxy)methyl)oxolan-2-yl)oxy)(hydroxy)phosphoryl)oxy)phosphonic acid[({[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]oxy}(hydroxy)phosphoryl)oxy]phosphonic acidRefChem:537483Pyrophosphate, Phosphoribosyl
Weitere Namen anzeigen
Uridine Impurity 30Phosphoribosyl-1-pyrophosphate5-Phosphoribosyl 1-diphosphatePhosphoribosylpyrophosphoric acidα-D-Ribofuranose,5-phosphate 1-pyrophosphateCiclopirox Impurity 2(Ciclopirox EP Impurity B )α-D-Ribofuranose 1-diphosphoric acid 5-phosphoric acidα-D-Ribofuranose, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate)
DTXCID301324595231-417-8PRPP5-Phospho-alpha-D-ribose 1-diphosphateAlpha-Phosphoribosylpyrophosphoric AcidPRib-PP5-Phosphoribosyl diphosphatephosphoribosylpyrophosphate

Datenbank-Bezeichner

CAS
13270-65-0、7540-64-9
PubChem CID
7339
DTXSID
DTXSID40895038
ChEMBL
CHEMBL1235437、CHEMBL606077
ChEBI
CHEBI:17111
UNII
W5555R4ERG
EC Number
231-417-8
Nikkaji
J40.073D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-5,8
Polarare Oberfläche (TPSA)
230 Ų
H-Brücken-Donoren
7
H-Brücken-Akzeptoren
14
Frei drehbare Bindungen
7
Schwere Atome
22

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Listed in ZINC15
Physical DescriptionSolid
Collision Cross Section161.1 Ų [M+Na-2H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

Physikochemische Eigenschaften

Siedepunkt
804.4 · 804.4±75.0 °C(Predicted)
Dichte
2.15 · 2.15±0.1 g/cm3(Predicted)
pka
0.96 · 0.96±0.50(Predicted)

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsErythrocyte
Cellular LocationsCytoplasm
Metabolite Pathways2-Hydroxyglutric Aciduria (D And L Form)

Anbieter3 Anbieter

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