Grundinformationen
- CAS
97-78-9- Standard-SMILES
CCCCCCCCCCCC(=O)N(C)CC(=O)O- InChIKey
BACYUWVYYTXETD-UHFFFAOYSA-N- Summenformel
- C15H29NO3
- Durchschnittliche Molmasse
- 271,4 g/mol
- Monoisotopische Masse
- 271,21474379
Überblick
N-Lauroylsarcosine is a N-acyl-amino acid.
Namen und Bezeichner
- Bevorzugter Name
- Lauroylsarcosine
- IUPAC
- 2-[dodecanoyl(methyl)amino]acetic acid
- Lokaler Name
- N-Lauroylsarkosin
- Englischer Name
- N-LAUROYLSARCOSINE
- Summenformel
- C15H29NO3
- Molmasse
- 271.4
Namen und Synonyme
N-LAUROYLSARCOSINE97-78-9Lauroyl sarcosineGlycine, N-methyl-N-(1-oxododecyl)-LauroylsarcosineHamposyl LMaprosyl LSarcosyl LN-LaurylsarcosineN-Lauroyl sarcosinateCrodasinic L2-(N-methyldodecanamido)acetic acid
Weitere Namen anzeigen
N-DODECANOYL-N-METHYLGLYCINEN-LAURYL SARCOSINESARKOSYL LSarcosinate LHN-Lauroylsarkosin
Nikkol sarcosinate LHN-Lauroyl-N-methylaminoacetic acidLIJ19P3L6FNSC-96994LOWENOL L ACIDSarkosyn-lauroyl sarcosinen-lauroylsarcosinate
Datenbank-Bezeichner
- CAS
97-78-9- PubChem CID
- 7348
- DTXSID
DTXSID7042011- ChEMBL
CHEMBL1907464- ChEBI
CHEBI:183705- UNII
- LIJ19P3L6F
- EC Number
- 202-608-3
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,5
- Polarare Oberfläche (TPSA)
- 57,6 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 12
- Schwere Atome
- 19
- Formalladung
- 0
- Komplexität
- 254
Experimentelle und physikochemische Eigenschaften
Chemical ClassesBiological Agents -> Amino Acids and Derivatives
Cosmetics
Cosmetic ingredients (Lauroyl Sarcosine) -> CIR (Cosmetic Ingredient Review)
Cleansing; Surfactant; Antistatic; Hair conditioning
SurfactantsSurfactant
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description
Liquid
White hygroscopic powder; [Sigma-Aldrich MSDS]
Collision Cross Section170.1 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID7042011]
Physikochemische Eigenschaften
- Schmelzpunkt
- 45 · 45-49 °C
- Siedepunkt
- 413.2 · 413.2±28.0 °C(Predicted)
- Dichte
- 0.97 · 0.97
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H315 (90.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P260, P261, P264, P264+P265, P271, P280, P284, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P320, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 173 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Glycine, N-methyl-N-(1-oxododecyl)-
Glycine, N-methyl-N-(1-oxododecyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Glycine, N-methyl-N-(1-oxododecyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: N-lauroylsarcosine (EC: 202-608-3)
Glycine, N-methyl-N-(1-oxododecyl)-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryA skin and strong eye irritant; [Sigma-Aldrich MSDS] See Sarcosine hydrochloride.
Hazard Classes and CategoriesSkin Irrit. 2 (90.2%)
Toxikologische Informationen
Health EffectsAcyl sarcosines may cause irritation to the skin and eyes. They may also react to produce N-nitrososarcosine, which is believed to be carcinogenic. (A2881)
Chemie und Industrie
Pharmakologische Informationen
Metabolism/Metabolites
Acyl sarcosines can be absorbed following oral or dermal contact, while nitrosamines can enter the body via ingestion, inhalation, or dermal contact. Once in the body, nitrosamines are metabolized by cytochrome P-450 enzymes, which essentially activates them into carcinogens. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase. (A2878, A2879, L1892)
MeSH Pharmacological Classification
Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties.
Verwendung und Herstellung
Uses
CIR ingredient: Lauroyl Sarcosine
Permitted for use as an inert ingredient in non-food pesticide products; [EPA]
Acyl sarcosines are used as hair-conditioning agents and surfactant-cleansing agents in cosmetics, as well as to improve wetting and penetration of topical pharmaceutical products. Acyl sarcosines and their sodium salts are also used in the metal finishing and processing industries for their crystal modifying, anti-rust, and anti-corrosion properties. (A2881)
U.S. Production2023: 88,531 lb
Industry UsesSurfactant (surface active agent)
Household ProductsInformation on 25 consumer products that contain Lauroyl sarcosine in the following categories is provided:
Use ClassificationCosmetics -> Cleansing; Surfactant; Antistatic; Hair conditioning
General Manufacturing Information
Zugehörige Reaktionen
3
Notizen zur Verbindung
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