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Grundinformationen
- Standard-SMILES
NC(=S)Nc1cccc2ccccc12- InChIKey
PIVQQUNOTICCSA-UHFFFAOYSA-N- Summenformel
- C11H10N2S
- Durchschnittliche Molmasse
- 202,282 g/mol
- Monoisotopische Masse
- 202,05646932
Namen und Bezeichner
- Bevorzugter Name
- 1-(1-Naphthyl)-2-thiourea
- IUPAC
- N-Naphthalen-1-ylthiourea
- Lokaler Name
- Antu (ISO)
- Englischer Name
- 1-(1-Naphthyl)-2-thiourea
- Summenformel
- C11H10N2S
- Molmasse
- 202.28
Namen und Synonyme
Datenbank-Bezeichner
- CAS
30553-04-9、86-88-4- PubChem CID
- 736366
- DTXSID
DTXSID8020919- ChEMBL
CHEMBL3182781- ChEBI
CHEBI:82256- UNII
- UKY0H6XJ4J
- EC Number
- 201-706-3
- Nikkaji
- J4.268D
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 193 °C · 193 °C
- Siedepunkt
- 377.6 · 377.6±25.0 °C(Predicted)
- Dichte
- 1.333 · 1.333
- Brechungsindex
- 1.55 · 1.5500 (estimate)
- storage temp.
- Poison room
- Löslichkeit
- 4.3 and · 4.3 and 86 g/L in acetone and triethylene glycol, respectively (Windholz et al., 1983)
- pka
- 13.12 · 13.12±0.70(Predicted)
- Aggregatzustand
- Crystals or Crystalline Powder
- Farbe
- Grayish to beige-brown
- Geruch (Odor)
- bitter taste
- Wasserlöslichkeit
- 600 mg/L · 600 mg/L at 20 °C (quoted, Windholz et al., 1983)
- Merck
- 14 · 14,722
- BRN
- 778118 · 778118
- Henry's Law Constant
- 1.2 · 1.2×103 mol/(m3Pa) at 25℃, HSDB (2015)
- Major Application
- agricultureenvironmental
- InChI
- 1S/C11H10N2S/c12-11(14)13-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H3,12,13,14)
- InChIKey
- PIVQQUNOTICCSA-UHFFFAOYSA-N
- SMILES
- NC(=S)Nc1cccc2ccccc12
- CAS Datenbank
- 86 · 86-88-4(CAS DataBase Reference)
- EPA chemische Informationen
- .alpha.-Naphthylthiourea (86-88-4)
Sicherheit und Regulatorisches
Sicherheitsdaten
- OEB
- C
- OEL
- TWA: 0.3 mg/m3
- wgk
- 2
- IDLA
- 100 mg/m3
- tsca
- TSCA listed
- ridadr
- UN 1651
- hs_code
- 29309090
- RTECS-Nr.
- YT9275000
- risk_code
- 28-40
- Toxizität
- Acute oral LD50 for Norwegian rats 6–8 mg/kg (Hartley and Kidd, 1987).
- hazard_code
- T+
- safety_code
- 28-36/37-45-25-23
- hazard_class
- 6.1
- packing_group
- II
- Speicherklasse
- 6.1A - Combustible, acute toxic Cat. 1 and 2very toxic hazardous materials
- Giftige Stoffe Daten
- 86-88-4(Hazardous Substances Data)
- Hazard Classifications
- Acute Tox. 2 OralCarc. 2
Chemie und Industrie
Anwendungen
Beschreibunga-Naphthylthiourea (ANTU; also called DIRAX) is toxic by inhalation, ingestion, or skin contact. Due to its very narrow spectrum of activity, production was discontinued a long time ago. Exposure to ANTU causes pulmonary edema; therefore, it is often used as an experimental pneumotoxin. ANTU is a graycolored, prism-shaped, odorless powder with a bitter taste. It has a molecular weight of 202.28 and melting point of 200 ℃ and does not ignite readily. However, on interaction with potential oxidizing agents, it may cause fire and explosions, which can lead to hazardous decomposition products such as sulfur dioxide, nitrogen dioxide, and carbon monoxide. The structure of ANTU contains the naphthalene chromophore, which absorbs UV light at ~311 nm. This suggests that ANTU can undergo photolysis.
VerwendenRodenticide. Specific control for the adult Norway rat; less toxic to other rat species.
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