HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 73641Erstellt: 4. November 2026
Arjunolic Acid
arjunolicaci · Arjulic acid · arjunolic acid · Arjunolic acid, 10 mM in DMSO · Arjunolic acid >=95% (LC/MS-ELSD) · 2,3,23-Trihydroxyolean-12-en-28-oic acid · Olean-12-en-28-oicacid, 2,3,23-trihydroxy-, (2a,3b,4a)- · (2alpha,3beta,4alpha)-2,3,23-Trihydroxy-olean-12-en-28-oic acid
https://huagongshe.com/de/chemical/73641
Identifikatoren & physikalische Daten
| CAS No. | 465-00-9 |
|---|
| Summenformel | C30H48O5 |
|---|
| Durchschnittliche Molmasse | 488,7 g/mol |
|---|
| Monoisotopische Masse | 488,35017463 g/mol |
|---|
| SMILES | CC1(C)CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@]43C)[C@@H]2C1 |
|---|
| InChIKey | RWNHLTKFBKYDOJ-DDHMHSPCSA-N |
|---|
| PubChem CID | 73641 |
|---|
| ChEMBL | CHEMBL464466 |
|---|
| ChEBI | CHEBI:68381 |
|---|
| DTXSID | DTXSID80963583 |
|---|
Chemische & physikalische Eigenschaften
| XLogP | 5,8 |
|---|
| Polarare Oberfläche (TPSA) | 98 |
|---|
| H-Brücken-Donoren | 4 |
|---|
| H-Brücken-Akzeptoren | 5 |
|---|
| Frei drehbare Bindungen | 2 |
|---|
| Schwere Atome | 35 |
|---|
| Formalladung | 0 |
|---|
| Komplexität | 941 |
|---|
| Schmelzpunkt | 332-334 °C |
|---|
| Siedepunkt | 606.0±55.0 °C(Predicted) |
|---|
| Dichte | 1.19±0.1 g/cm3(Predicted) |
|---|
| Lagerbedingungen | -20°C |
|---|
| Löslichkeit | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
|---|
| Aggregatzustand | Powder |
|---|
| pKa (Säurekonstante) | 4.62±0.70(Predicted) |
|---|
| Farbe | White to off-white |
|---|
| Hauptanwendungen | metabolomicsvitamins, nutraceuticals, and natural products |
|---|
| InChIKey | RWNHLTKFBKYDOJ-QBUVGUFVNA-N |
|---|
| SMILES | [C@@H]1(O)C[C@@]2([C@@]3([H])CC=C4[C@]5([C@](C(O)=O)(CCC(C)(C)C5)CC[C@@]4(C)[C@]3(C)CC[C@@]2([H])[C@](C)(CO)[C@H]1O)[H])C |&1:0,3,4,9,10,22,24,28,30,34,r| |
|---|
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|
| Lagerklasse | 11 - Combustible Solids |
|---|
Anwendungen & Verwendung
Beschreibung
Arjunolic acid is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay when used at a concentration of 0.8 mM. Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain. It reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at doses of 100 and 250 mg/kg for 20 days. Arjunolic acid reduces renal fibrosis and increases in kidney TNF-α and IL-1β levels induced by cisplatin in mice when administered at doses of 100 and 250 mg/kg per day for 10 days.
