1,3-Oxazolidin-2-on
2-Oxazolidinone
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
497-25-6- Standard-SMILES
O=C1NCCO1- InChIKey
IZXIZTKNFFYFOF-UHFFFAOYSA-N- Summenformel
- C3H5NO2
- Durchschnittliche Molmasse
- 87,08 g/mol
- Monoisotopische Masse
- 87,0320284
Überblick
Oxazolidin-2-one is an oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2. It has a role as a metabolite. It is a carbamate ester and an oxazolidinone.
Namen und Bezeichner
- Bevorzugter Name
- 2-Oxazolidinone
- IUPAC
- 1,3-oxazolidin-2-one
- Lokaler Name
- 1,3-Oxazolidin-2-on
- Englischer Name
- 2-Oxazolidone
- Summenformel
- C3H5NO2
- Molmasse
- 87.08
Namen und Synonyme
2-OxazolidinoneOxazolidin-2-one2-Oxazolidone497-25-61,3-Oxazolidin-2-oneOxazolidoneCHEBI:1237Z4D49W92PPNSC-35382NSC-38240Carbamic acid, (2-hydroxyethyl)-, gamma-lactoneDTXSID2074326
Weitere Namen anzeigen
OxazolidineNSC 353822-Oxazolinone2-OXAZOLIDIONE2-OX2-Oxa
2 oxazolidinone2 OxazolidoneOxazolidin 2 one1,3 Oxazolidin 2 one1,3-oxazolidine-2-oneRefChem:1688681,3 Oxazolidine 2 oneDTXCID4040719
Datenbank-Bezeichner
- CAS
497-25-6、51667-26-6- PubChem CID
- 73949
- DTXSID
DTXSID2074326- ChEMBL
CHEMBL1867161- ChEBI
CHEBI:1237- UNII
- Z4D49W92PP
- EC Number
- 207-840-9
- Nikkaji
- J36.850D
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- -0,3
- Polarare Oberfläche (TPSA)
- 38,3 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 6
- Formalladung
- 0
- Komplexität
- 71,2
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Other Nitrogen Compounds
SpringerMaterials PropertiesCrystal structure
Solubility>13.1 [ug/mL] (The mean of the results at pH 7.4)
Physical DescriptionBeige crystalline solid; [Sigma-Aldrich MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 83 · 83-87 °C(lit.)
- Siedepunkt
- 220 °C48 · 220 °C48 mm Hg(lit.)
- Dichte
- 1.2736 · 1.2736 (rough estimate)
- Brechungsindex
- 1.494 · 1.4940 (estimate)
- Flammpunkt
- 220 °C/48mm · 220°C/48mm
- storage temp.
- Sealed in dry,Room Temperature
- Löslichkeit
- Chloroform (Slightly, Heated), Methanol (Slightly)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 47.4% (36 of 76) of reports.
Warning
H302 (51.3%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 76 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: 2-Oxazolidinone
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Hazards SummaryA strong eye irritant; May cause skin sensitization; Harmful by ingestion; [Sigma-Aldrich MSDS] Search for (497-25-6[EC/RN Number]) AND (allergic OR dermatitis OR sensitizer OR sensitization): no results; [PubMed]
Hazard Classes and CategoriesAcute Tox. 4 (51.3%)
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29322980
- RTECS-Nr.
- RQ2450000
- risk_code
- 22-36-43-40-36/37/38
- Toxizität
- TDLo orl-mus: 1000 mg/kg:ETA BCPCA62,168,59
- hazard_code
- Xn,Xi
- safety_code
- 26-36/37-37-36
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
Verwendung und Herstellung
UsesDerivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents. [ChemIDplus]
General Manufacturing Information2-Oxazolidinone: ACTIVE
Anwendungen
VerwendenAs an oxazole derivative used as an antibiotic, 2-Oxazolidone is also used in the preparation of compounds with antitumor activity and as a metabolite of Furazolidone (F864100).
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Zugehörige Reaktionen
513
Notizen zur Verbindung
Wird geladen…