Trehalose

HCID 7427CAS 99-20-7
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Grundinformationen

Standard-SMILES
OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChIKey
HDTRYLNUVZCQOY-LIZSDCNHSA-N
Summenformel
C12H22O11
Durchschnittliche Molmasse
342,3 g/mol
Monoisotopische Masse
342,11621152

Überblick

Alpha,alpha-trehalose is a trehalose in which both glucose residues have alpha-configuration at the anomeric carbon. It has a role as a geroprotector, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human metabolite.

Namen und Bezeichner

Bevorzugter Name
Trehalose
IUPAC
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol
Lokaler Name
Trehalose
Englischer Name
Trehalose
Summenformel
C12H22O11
Molmasse
342.3

Namen und Synonyme

trehalose99-20-7D-(+)-TrehaloseMycosealpha,alpha-trehaloseErgot sugaralpha-D-TrehaloseCabalettaMushroom sugarNatural trehalosealpha-D-glucopyranosyl-alpha-D-glucopyranosidealpha,alpha'-Trehalose
Weitere Namen anzeigen
α,α-trehaloseD-TREHALOSEalpha-d-glucopyranosideTrehalose RSalpha-TrehaloseTrehalose solution
alpha-D-glucopyranosyl alpha-D-glucopyranosideCHEBI:16551B8WCK70T7INSC-2093(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-3,4,5-triolCHEBI:27082(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy)oxane-3,4,5-triol

Datenbank-Bezeichner

CAS
99-20-7
PubChem CID
7427
DTXSID
DTXSID3048102
ChEMBL
CHEMBL1236395
ChEBI
CHEBI:16551
UNII
B8WCK70T7I
EC Number
202-739-6
Nikkaji
J4.965D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-4,2
Polarare Oberfläche (TPSA)
190 Ų
H-Brücken-Donoren
8
H-Brücken-Akzeptoren
11
Frei drehbare Bindungen
4
Schwere Atome
23

Experimentelle und physikochemische Eigenschaften

Chemical ClassesBiological Agents -> Disaccharides
DrugsPharmaceuticals -> Listed in ZINC15
Cosmetics · 2 Einträge

Cosmetic ingredients (Trehalose) -> CIR (Cosmetic Ingredient Review)

Humectant; Moisturising

Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Melting Point203 °C
Physical Description · 2 Einträge

Dihydrate: Solid; [Merck Index] White or nearly white solid; [JECFA] White crystalline powder; [Acros Organics MSDS]

Solid

Physikochemische Eigenschaften

Schmelzpunkt
203 °C · 203 °C
Siedepunkt
397.76 °C · 397.76°C (rough estimate)
Dichte
1.58 · 1.5800
Dampfdruck
0.001 Pa · 0.001Pa at 25℃
Brechungsindex
197 ° · 197 ° (C=7, H2O)
storage temp.
Inert atmosphere,Room Temperature

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 99.8% (429 of 430) of all reports.

Not Classified

Aggregated GHS information provided per 430 reports by companies from 2 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: .alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosyl

Status: Active Update: 02-05-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/26864

.alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosyl: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Hazards SummaryNot toxic or mutagenic in subchronic toxicity studies; [ToxPlanet: Health Council of the Netherlands] The dihydrate is the product of commerce (CAS# 6138-23-4); [JECFA] May cause irritation; [Acros Organics MSDS]
Hazard Classes and CategoriesNot Classified

Toxikologische Informationen

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Sicherheitsdaten

wgk
WGK 1
tsca
TSCA listed
hs_code
29400090
risk_code
38
hazard_code
Xi
safety_code
37/39-26

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsEpidermis
Cellular LocationsExtracellular
Metabolite PathwaysTrehalose Degradation

Verwendung und Herstellung

Uses · 2 Einträge

CIR ingredient: Trehalose

Disaccharide present in fungi, bacteria, yeasts, and insects; Used to stabilize cells during freeze-drying and air-drying, as a sweetener and stabilizer in foods, and as an additive in cosmetics; [Merck Index] Used as a texturizer, stabilizer, humectant, and sweetener in foods; [JECFA]

Household ProductsInformation on 31 consumer products that contain Trehalose in the following categories is provided:
Use Classification · 3 Einträge

Food Additives -> HUMECTANT; STABILIZER; SWEETENER; TEXTURIZER; THICKENER -> JECFA Functional Classes

Food Additives -> HUMECTANT; STABILIZER; SWEETENER; TEXTURIZER; THICKENER -> JECFA Functional Classes

Cosmetics -> Humectant; Moisturising

General Manufacturing Information.alpha.-D-Glucopyranoside, .alpha.-D-glucopyranosyl: ACTIVE

Anwendungen

Verwendentrehalose is a humectant and moisturizer, it helps bind water in the skin and increase the skin’s moisture content. It is a naturally occurring plant sugar.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Nachgelagerte Produkte

Anbieter50 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon.

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