CAS 2002-24-6 Ethanolamine Hydrochloride (HCID 74819)

Überblick

The CIR Expert Panel concluded that ethanolamine and the 12 related ethanolamine salts, listed below, are safe in the present practices of use and concentration described in this safety assessment (rinse-off products only) when formulated to be non-irritating. The Panel cautioned that ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Ethanolamine HCl...

Namen und Bezeichner

Bevorzugter Name: Ethanolamine Hydrochloride
IUPAC: 2-aminoethanol;hydrochloride
Lokaler Name: 2-Hydroxyethylammoniumchlorid
Englischer Name: Ethanolamine hydrochloride
Summenformel: C2H8ClNO
Molmasse: 97.54

Namen und Synonyme

2-Aminoethanol hydrochlorideEthanolamine hydrochloride2002-24-6Ethanolamine HCl2-Aminoethanol HClbeta-Aminoethanol hydrochlorideUNII-KKP3YYL02FKKP3YYL02FEINECS 217-900-6NSC 10000NSC 30601NSC 41218

Weitere Namen anzeigen

MONOETHANOLAMINE HYDROCHLORIDEETHANOLAMINE HYDROCH2-Aminoethan-1-ol hydrochloridemeahydrochlorideMONOETHANOLAMINE HCLethanolaminechloridecolaminehydrochlorideEthanolammoniumchlorid

NSC-10000NSC-30601NSC-41218DTXSID8049593ETHANOLAMINE HYDROCHLORIDE [II]ETHANOLAMINE HYDROCHLORIDE [MI]ETHANOLAMINE HYDROCHLORIDE (II)2Aminoethanol HCl

Datenbank-Bezeichner

CAS: 2002-24-6
PubChem CID: 74819
DTXSID: DTXSID8049593
UNII: KKP3YYL02F
EC Number: 217-900-6

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA): 46,3 Å²
H-Brücken-Donoren: 3
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 1
Schwere Atome: 5
Formalladung: 0
Komplexität: 10

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Ethanolamines

Cosmetics · 2 Einträge

Cosmetic ingredients (Ethanolamine HCl) -> CIR (Cosmetic Ingredient Review)

Buffering

Physical Description · 2 Einträge

Liquid

Deliquescent solid; [Merck Index] White hygroscopic powder; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt: 82 · 82-84 °C(lit.)
Dichte: 1.07 g/cm3 · 1.07g/cm3 at 20—25°C1.12g/cm3 at 20—25°C
storage temp.: 30 °C · Store below +30°C.
Löslichkeit: DMSO (Slightly, Heated)
Aggregatzustand: Agglomerating Crystals
Wichte: 1.146 · 1.146
Farbe: White or slightly beige
Geruch (Odor): Odorless
PH: 9 · 9—10
pka: 9.5 · 9.5(at 25℃)
Wasserlöslichkeit: almost transparency
Merck: 14 · 14,3727
BRN: 3542892 · 3542892
Stabilität: Hygroscopic
Kosmetik-Inhaltsstoffe Funktionen: BUFFERING
InChI: 1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChIKey: PMUNIMVZCACZBB-UHFFFAOYSA-N
SMILES: NCCO.[H]Cl
LogP: -1.308 · -1.308 (est)
CAS Datenbank: 2002 · 2002-24-6(CAS DataBase Reference)
EPA chemische Informationen: 2 · Ethanol, 2-amino-, hydrochloride (2002-24-6)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 3.2% (7 of 220) of reports.

Warning

H290 (10%): May be corrosive to metals [Warning Corrosive to Metals]

P234, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 220 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Ethanol, 2-amino-, hydrochloride

Ethanol, 2-amino-, hydrochloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Ethanol, 2-amino-, hydrochloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Ethanol, 2-amino-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Ethanol, 2-amino-, hydrochloride: Human health tier I assessment

Hazards SummaryDecreased average litter size and increased post-implantation loss observed in 2-generation oral study of rats at doses maternally toxic (1,000 mg/kg/day); [EPA - TSCATS] A skin and strong eye irritant; [Alfa Aesar MSDS] See Ethanolamine.

Hazard Classes and CategoriesMet. Corr. 1 (10%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The CIR Expert Panel concluded that ethanolamine and the 12 related ethanolamine salts, listed below, are safe in the present practices of use and concentration described in this safety assessment (rinse-off products only) when formulated to be non-irritating. The Panel cautioned that ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Ethanolamine HCl...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

F: 3-10
wgk: 1
tsca: TSCA listed
hs_code: 29221100
RTECS-Nr.: KJ6370000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36/37/39
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Verwendung und Herstellung

Uses · 3 Einträge

CIR ingredient: Ethanolamine HCl

Used to remove carbon dioxide and hydrogen sulfide from natural gas and in the production of surfactants, antibiotics, polishes, hair waving solutions, and emulsifiers; Also used as a softening agent (hides) and dispersing agent (agricultural chemicals); [Merck Index]

Leather Tanning and Processing [Category: Industry]

U.S. Production2023: <75,000 lb

Industry UsesAnti-scaling agent

Use ClassificationCosmetics -> Buffering

General Manufacturing Information · 2 Einträge

Oil and Gas Drilling, Extraction, and Support activities

Ethanol, 2-amino-, hydrochloride (1:1): ACTIVE

Anwendungen · 1 Eintrag

VerwendenEthanolamine hydrochloride has been used:in overnight incubation of the tips to attach primary amine groups at the tip surfacein the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumorsto administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process