Butyl Glycolate (HCID 81882)

Überblick

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Butyl Glycolate...

Namen und Bezeichner

Bevorzugter Name: Butyl Glycolate
IUPAC: butyl 2-hydroxyacetate
Lokaler Name: Butylglykolat
Englischer Name: Butyl hydroxyacetate
Summenformel: C6H12O3
Molmasse: 132.16

Namen und Synonyme

Butyl glycolatebutyl 2-hydroxyacetate7397-62-8Butyl hydroxyacetateAcetic acid, hydroxy-, butyl estern-butyl glycolateDTXSID60447253H5QAS0HZXAcetic acid, 2-hydroxy-, butyl esterUNII-3H5QAS0HZXGlycolic acid, butyl esterEINECS 230-991-7

Weitere Namen anzeigen

Polysolvan OButyl hydroxyacetate ISO 9001：2015 REACHPolysolvan 0butyl glycollateButhyl Glycolate

BUTOXYCARBONYLMETHANOLAI3-07975DTXCID4024725EC 230-991-7RefChem:122255BUTYL GLYCOLATE [INCI]230-991-7VFGRALUHHHDIQI-UHFFFAOYSA-N

Datenbank-Bezeichner

CAS: 7397-62-8
PubChem CID: 81882
DTXSID: DTXSID6044725
ChEMBL: CHEMBL3184386
UNII: 3H5QAS0HZX
EC Number: 230-991-7
Nikkaji: J39.924H

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 0,7
Polarare Oberfläche (TPSA): 46,5 Å²
H-Brücken-Donoren: 1
H-Brücken-Akzeptoren: 3
Frei drehbare Bindungen: 5
Schwere Atome: 9
Formalladung: 0
Komplexität: 80,4

Experimentelle und physikochemische Eigenschaften

CosmeticsCosmetic ingredients (Butyl Glycolate) -> CIR (Cosmetic Ingredient Review)

SpringerMaterials PropertiesSurface tension

Physikochemische Eigenschaften

Siedepunkt: 187 · 187-190 °C(lit.)
Dichte: 1.019 g/mL · 1.019 g/mL at 20 °C(lit.)
Dampfdruck: 1.3 hPa · 1.3hPa at 20℃
Brechungsindex: 20 · n20/D 1.427
Flammpunkt: 74 °C · 74 °C
storage temp.: 2 · 2-8°C
pka: 12.99 · 12.99±0.10(Predicted)
Wasserlöslichkeit: 46 g/L · 46g/L at 20℃
BRN: 1749477 · 1749477
Kosmetik-Inhaltsstoffe Funktionen: SKIN CONDITIONING
InChI: InChI=1S/C6H12O3/c1-2-3-4-9-6(8)5-7/h7H,2-5H2,1H3
InChIKey: VFGRALUHHHDIQI-UHFFFAOYSA-N
SMILES: C(OCCCC)(=O)CO
LogP: 0.38 at · 0.38 at 25℃
CAS Datenbank: 7397 · 7397-62-8(CAS DataBase Reference)
NIST chemische Informationen: Butyl glycolate(7397-62-8)
EPA chemische Informationen: Acetic acid, hydroxy-, butyl ester (7397-62-8)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.2% (6 of 2726) of reports.

Danger

H318 (99.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]

P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)

Aggregated GHS information provided per 2726 reports by companies from 12 notifications to the ECHA C&L Inventory.

Warning

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Acetic acid, hydroxy-, butyl ester

Status: Active Update: 17-01-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/23612

Acetic acid, hydroxy-, butyl ester: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2 Einträge

Eye Dam. 1 (99.8%)

Flammable liquids - Category 4

Toxikologische Informationen

Toxicity Summary · 2 Einträge

Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Butyl Glycolate...

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk: 1
tsca: TSCA listed
ridadr: NA 1993 / PGIII
risk_code: 63-41
hazard_code: Xn
safety_code: 23-24/25-36/37/39-26
Speicherklasse: 10 - Combustible liquids
Hazard Classifications: Eye Dam. 1Repr. 2

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: Butyl Glycolate

General Manufacturing InformationAcetic acid, 2-hydroxy-, butyl ester: ACTIVE

Anwendungen · 1 Eintrag

VerwendenButyl glycolate may be used in the preparation of N-(α-hydroxyacetyl)-(S)-isoleucine. n-Butyl glycolate is used primarily as a varnish additive, valued because of its low volatility. Trade names include PolysolvanO (Hoechst) and GB-Ester (Wacker). It confers smooth spreading properties and high gloss on nitrocellulose varnish. For acetyl cellulose, it is effective as a blush inhibitor under conditions of high humidity. Due to its good blending properties, n-butyl glycolate is also used as an additive in alkyd resins and oil-based paints.