HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mecrilat
CA-7 · Coapt · Coapt. · Adhere · Cyanolit · Mecrilat · Mecrilate · mecrylate
Identifikatoren & physikalische Daten
| CAS No. | 137-05-3 |
|---|---|
| Summenformel | C5H5NO2 |
| Durchschnittliche Molmasse | 111,1 g/mol |
| Monoisotopische Masse | 111,0320284 g/mol |
| SMILES | C=C(C#N)C(=O)OC |
| InChIKey | MWCLLHOVUTZFKS-UHFFFAOYSA-N |
| PubChem CID | 8711 |
| ChEMBL | CHEMBL2106424 |
| EC No. | 205-275-2 |
| DTXSID | DTXSID4025589 |
| Lokaler Name | Mecrilat |
Chemische & physikalische Eigenschaften
| XLogP | 0,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 50,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 163 |
| Stoffklassen | Flammable agents - 2nd degree |
| Polymers | Plastics & Rubber -> (Meth)acrylates |
| SpringerMaterials Properties | Boiling point |
| LogP (Verteilungskoeffizient) | 0.03 (estimated) |
| Geruch | Strong, acrid odorCharacteristic odor |
| Dichte | 1.1044 at 81 °F (NTP, 1992) - Denser than waterwill sink1.1012 g/cu cm at 20 °CRelative density (water = 1): 1.11.1012 @25 °C(81 °F): 1.10nD25 1.443. d20 1.1044 |
| Viscosity | 2.2 cP at 25 °C |
| Color/Form | Clear, colorless liquidThick liquid |
| Löslichkeit | less than 1 mg/mL at 72 °F (NTP, 1992)Soluble or partially soluble in methyl ethyl ketone, toluene, DMF /dimethylformamide/, acetone, nitromethane30% |
| Flammpunkt | 174 °F (NIOSH, 2024)82.78 °C (closed cup)79 °C |
| Siedepunkt | 117 to 120 °F at 1.8 mmHg (NTP, 1992)47 °C at 2 mm HgBP: 47-49 °C (0.33-0.36 kPa)66 °C117-120 °F at 1.8 mmHg200.5 °C @760 [mm Hg]bp 48-49° |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides and CN-/.Decomposition: degradation products include formaldehydethermal decomposition products may include highly toxic fumes of hydrogen cyanide and toxic oxides of carbon and nitrogen. |
| Schmelzpunkt | -40 °C |
| Dampfdruck | 49hPa at 20℃ |
| Brechungsindex | n20D 1.4459 |
| Aggregatzustand | Colorless liquid |
| InChI | InChI=1S/C5H5NO2/c1-4(3-6)5(7)8-2/h1H2,2H3 |
| InChIKey | MWCLLHOVUTZFKS-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C(C#N)=C |
| LogP (Verteilungskoeffizient) | 0.24 at 25℃ and pH7 |
| EPA chemische Informationen | Methyl 2-cyanoacrylate (137-05-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315: Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
|---|---|
| Regulatorische Informationen | Chemical: 2-Propenoic acid, 2-cyano-, methyl esterREACH registered substance: Mecrilate (EC: 205-275-2)Methyl 2-cyanoacrylate: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| DOT-Kennzeichnung | Combustible Liquid |
| Brandgefahren | Flash point data for this compound are not available but it is probably non-flammable. (NTP, 1992)Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 79 °C explosive vapour/air mixtures may be formed. |
| Gesundheitsgefahren | Excerpt from NIOSH Pocket Guide for Methyl-2-cyanoacrylate: |
| Gefahrenübersicht | Asthma: Occupational asthma due to methyl methacrylate and cyanoacrylate. [Lozewicz S et al. Thorax 1985 Nov40(11):836-9]A potential skin sensitizer[ICSC] DSEN and RSEN notations recommended[ACGIH] |
| Reaktive Gruppe | Nitriles |
| EG-Einstufung | Symbol: XiR: 36/37/38S: (2)-23-24/25-26 |
| Special Reports | WHOConcise International Chemical Assessment Document 36, Methyl Cyanoacrylate and Ethyl Cyanoacrylate (2001). CICADs are concise documents that provide summaries of the relevant scientific information concerning the potential effects of chemicals upon human health and/or the environment. The primary objective of CICADs is characterization of hazard and dose-response from exposure to a chemical.[Available from, as of February 15, 2011: http://www.inchem.org/documents/cicads/cicads/cicad36.htm] |
Anwendungen & Verwendung
Beschreibung
Methyl cyanoacrylate (MCA) is an organic compound that contains several functional groups, a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues.It can be encountered under many trade names. Methyl cyanoacrylate is less commonly encountered than ethyl cyanoacrylate. It is soluble in acetone, methyl ethyl ketone, nitro methane, and dichloromethane. MCA polymerizes rapidly in presence of moisture.
Verwenden
Surgical aid (tissue adhesive).