Grundinformationen
- Standard-SMILES
O=C([O-])CC(O)C(=O)[O-].[Na+].[Na+]- InChIKey
WPUMTJGUQUYPIV-UHFFFAOYSA-L- Summenformel
- C4H4Na2O5
- Durchschnittliche Molmasse
- 178,05 g/mol
- Monoisotopische Masse
- 177,98541179
Überblick
On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.
Namen und Bezeichner
- Bevorzugter Name
- Malic acid, disodium salt
- IUPAC
- disodium;2-hydroxybutanedioate
- Englischer Name
- DL-Malic acid disodium salt
- Summenformel
- C4H4Na2O5
- Molmasse
- 178.05
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
22798-10-3、40520-93-2、676-46-0- PubChem CID
- 8736
- DTXSID
DTXSID7046831- ChEMBL
CHEMBL182856- UNII
- 2EFF9N315F
- EC Number
- 211-627-6、254-952-9、866-020-4
- Nikkaji
- J3.317K
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 100 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 11
- Formalladung
- 0
- Komplexität
- 118
Experimentelle und physikochemische Eigenschaften
Cosmetics
Cosmetic ingredients (Sodium Malate) -> CIR (Cosmetic Ingredient Review)
Humectant; Skin conditioning
Physikochemische Eigenschaften
- Schmelzpunkt
- 300 °C · >300 °C(lit.)
- CAS Datenbank
- 22798 · 22798-10-3(CAS DataBase Reference)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 45.8% (65 of 142) of reports.
Warning
H315 (41.5%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 142 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
This chemical does not meet GHS hazard criteria for 100% (37 of 37) of all reports.
Gefahrenhinweise
Regulatory Information
Chemical: Butanedioic acid, hydroxy-, disodium salt
Disodium malate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Skin Irrit. 2 (41.5%)
Skin Irrit. 2 (100%)
Not Classified
Toxikologische Informationen
Toxicity Summary
On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.
Safe for use in cosmetics, with qualifications
Sicherheitsdaten
- wgk
- 3
- RTECS-Nr.
- ON7730000
Chemie und Industrie
Verwendung und Herstellung
Use Classification
Food additives
Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes
Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes
Cosmetics -> Humectant; Skin conditioning
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