Malic acid, disodium salt

HCID 8736CAS 22798-10-3

Grundinformationen

Standard-SMILES
O=C([O-])CC(O)C(=O)[O-].[Na+].[Na+]
InChIKey
WPUMTJGUQUYPIV-UHFFFAOYSA-L
Summenformel
C4H4Na2O5
Durchschnittliche Molmasse
178,05 g/mol
Monoisotopische Masse
177,98541179

Überblick

On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.

Namen und Bezeichner

Bevorzugter Name
Malic acid, disodium salt
IUPAC
disodium;2-hydroxybutanedioate
Englischer Name
DL-Malic acid disodium salt
Summenformel
C4H4Na2O5
Molmasse
178.05

Namen und Synonyme

Malic acid, disodium saltRefChem:887666Sodium malate676-46-0Disodium malateDL-Malic acid disodium saltdisodium 2-hydroxybutanedioateDisodium DL-malate22798-10-3disodium;2-hydroxybutanedioateSODIUM DL-MALATESodium 2-hydroxysuccinate
Weitere Namen anzeigen
DISODIUM DL-MALATE HYDRATEMALIC ACID, SODIUMDI-SODIUM DL-MALATEDL-MALIC ACID SODIUMMalicaciddisodiumsaltdl-malic acid disodiumDl-MalicAcid,SodiumSaltSODIUM DL-MALATE HYDRATEDI-SODIUM MALATE 0.5-WATER
Sodium DL-maleateButanedioic acid, hydroxy-, disodium saltDTXSID7046831malic acid sodium saltMFCD00012466L-HYDROXYBUTANEDIOICACIDDISODIUMSALT2EFF9N315F63474-37-3

Datenbank-Bezeichner

CAS
22798-10-3、40520-93-2、676-46-0
PubChem CID
8736
DTXSID
DTXSID7046831
ChEMBL
CHEMBL182856
UNII
2EFF9N315F
EC Number
211-627-6、254-952-9、866-020-4
Nikkaji
J3.317K

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
100 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
5
Frei drehbare Bindungen
1
Schwere Atome
11

Experimentelle und physikochemische Eigenschaften

Cosmetics · 2 Einträge

Cosmetic ingredients (Sodium Malate) -> CIR (Cosmetic Ingredient Review)

Humectant; Skin conditioning

SolubilityFreely soluble in water
Physical DescriptionWhite crystalline powder or lumps

Physikochemische Eigenschaften

Schmelzpunkt
300 °C · >300 °C(lit.)
CAS Datenbank
22798 · 22798-10-3(CAS DataBase Reference)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 45.8% (65 of 142) of reports.

Warning

H315 (41.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 142 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

This chemical does not meet GHS hazard criteria for 100% (37 of 37) of all reports.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: Butanedioic acid, hydroxy-, disodium salt

Disodium malate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Butanedioic acid, hydroxy-, disodium salt: Human health tier I assessment
Hazard Classes and Categories · 3 Einträge

Skin Irrit. 2 (41.5%)

Skin Irrit. 2 (100%)

Not Classified

Toxikologische Informationen

Toxicity Summary · 2 Einträge

On the basis of the animal and clinical data included in this report, the CIR Expert Panel concludes that Malic Acid and Sodium Malate are safe for use as pH adjusters in cosmetic formulations. The Expert Panel determined that the data are insufficient to determine the safety of these ingredients for any other functions.

Safe for use in cosmetics, with qualifications

Sicherheitsdaten

wgk
3
RTECS-Nr.
ON7730000

Chemie und Industrie

Verwendung und Herstellung

UsesCIR ingredient: Sodium Malate
Use Classification · 4 Einträge

Food additives

Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes

Flavouring Agent -> FLAVOURING_AGENTFood Additives -> ACIDITY_REGULATOR -> JECFA Functional Classes

Cosmetics -> Humectant; Skin conditioning

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]

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