1-Bromdodecan
1-Bromododecane
Grundinformationen
- CAS
143-15-7- Standard-SMILES
CCCCCCCCCCCCBr- InChIKey
PBLNBZIONSLZBU-UHFFFAOYSA-N- Summenformel
- C12H25Br
- Durchschnittliche Molmasse
- 249,23 g/mol
- Monoisotopische Masse
- 248,11396
Namen und Bezeichner
- Bevorzugter Name
- 1-Bromododecane
- IUPAC
- 1-bromododecane
- Lokaler Name
- 1-Bromdodecan
- Englischer Name
- 1-Bromododecane
- Summenformel
- C12H25Br
- Molmasse
- 249.23
Namen und Synonyme
1-Bromododecane143-15-7Lauryl bromideDodecyl bromideDodecane, 1-bromo-DTXSID2044395DTXCID002439590T93TX09DNSC-6786RefChem:75159205-587-9n-Dodecyl bromide
Weitere Namen anzeigen
1-DodecylbromideBROMODODECANLaurlybromideJACS-143-15-7Lauroylbromide1-Dodecylbromid1-bromo-dodecan
Dodecane, bromo-bromododecaneC12H25Br1-bromo dodecane1-bromo-dodecane1-BROMO-N-DODECANE1-dodecyl-bromideMFCD00000225
Datenbank-Bezeichner
- CAS
143-15-7- PubChem CID
- 8919
- DTXSID
DTXSID2044395- ChEMBL
CHEMBL3184907- UNII
- 90T93TX09D
- EC Number
- 205-587-9
- Nikkaji
- J2.029J
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 7,1
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 0
- Frei drehbare Bindungen
- 10
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 81,2
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Classes -> Halogenated Aliphatics, Saturated
SpringerMaterials PropertiesBoiling point
Density1.038 @25 °C
Physical Description
Liquid
Liquid; [Merck Index] Colorless liquid with a weak odor; [Alfa Aesar MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 11 · −11-−9 °C(lit.)
- Siedepunkt
- 134 · 134-135 °C6 mm Hg(lit.)
- Dichte
- 1.04 g/mL · 1.040 g/mL at 20 °C
- Dampfdichte
- 8.6 · 8.6 (vs air)
- Brechungsindex
- 20 · n20/D 1.458(lit.)
- Flammpunkt
- 230 °F · >230 °F
- storage temp.
- 2 · Sealed in dry,2-8°C
- Löslichkeit
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 22.9% (58 of 253) of reports.
Danger
H304 (41.1%): May be fatal if swallowed and enters airways [Danger Aspiration hazard]
P261, P264, P264+P265, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P331, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 253 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Dodecane, 1-bromo-
Dodecane, 1-bromo- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecane, 1-bromo- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: 1-bromododecane (EC: 205-587-9)
Dodecane, 1-bromo-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Alfa Aesar MSDS] See 1-Bromopropane and 2-Bromopentane.
Hazard Classes and CategoriesAsp. Tox. 1 (41.1%)
Sicherheit und Schutzausrüstung
Protective Action Criteria (PAC)
12 [mg/m3]
130 [mg/m3]
790 [mg/m3]
Chemie und Industrie
Verwendung und Herstellung
U.S. Production2023: 250,000 - <550,000 lb
Consumer UsesAbrasives
Industry UsesAbrasives
General Manufacturing Information
Mining (except Oil and Gas) and support activities
Dodecane, 1-bromo-: ACTIVE
Anwendungen
Verwenden1-Bromododecane is used as a solvent. It is used as an intermediate to manufacture surfactant, pharmaceuticals and other organic compounds.
Verwenden1-Bromododecane have assumed considerable importance as starting materials for the production of many types of organic derivatives. The major use for 1-Bromododecane with 12 – 16 carbon atomsisinthe production of alkyldimethylamines by the nucleophilic displacement of bromide ion with dimethylamine. These amines are used as intermediates in the manufacture of fatty amine oxides and alkyl dimethyl benzyl quaternary ammonium salts, which are used in a wide range of products because of their biological (germicidal) or physical (cationic) properties. Minor amounts of 1-Bromododecane are used to produce insect pheromones, phasetransfer catalysts, and other useful specialty chemicals.
Darstellung
synthetische1-Bromododecane is synthesized by the action of 1-dodecanol and hydrobromic acid. The 1-dodecanol is added to the enameled glass reaction pot, stirred and cooled, and sulfuric acid is slowly added. Stir for 1h, then add hydrobromic acid. The temperature is gradually increased to 90-95℃, and the reaction is stirred for 8h. After the reaction, the temperature is lowered to 30℃ and left for 8h. The acid layer is separated, and the oil layer is adjusted to pH 8 with dilute alkali solution, and the alkali solution is separated and washed with 50% ethanol. Distill under reduced pressure and collect 140-200℃ (3.33kPa) fractions to obtain refined 1-bromododecane.
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