3-Amino-1-propanol

HCID 9086CAS 156-87-6

Grundinformationen

Standard-SMILES
NCCCO
InChIKey
WUGQZFFCHPXWKQ-UHFFFAOYSA-N
Summenformel
C3H9NO
Durchschnittliche Molmasse
75,11 g/mol
Monoisotopische Masse
75,06841391

Überblick

N-propanolamine is a colorless to pale yellow liquid with a fishy odor. Less dense than water. Melting point 12.4 °C (54 °F). Moderately toxic by ingestion.

Namen und Bezeichner

Bevorzugter Name
3-Amino-1-propanol
IUPAC
3-aminopropan-1-ol
Lokaler Name
3-Amino-1-propanol
Englischer Name
3-Aminopropanol
Summenformel
C3H9NO
Molmasse
75.11

Namen und Synonyme

3-Aminopropan-1-ol3-Aminopropanol3-Amino-1-propanol156-87-61-Propanol, 3-amino-PROPANOLAMINE3-Aminopropyl alcohol3-Propanolamine3-Hydroxypropylamine1-Amino-3-propanol1,3-Propanolamine1-Amino-3-hydroxypropane
Weitere Namen anzeigen
monopropanolamine3-Hydroxy-1-aminopropane3-AIMNOPROPANOL
beta-Alaninolgamma-Aminopropanol3-Hydroxy-1-propylaminegamma-Hydroxy-1-propylamineYMA7C44XGYNSC-7766DTXSID0059746CHEBI:143408

Datenbank-Bezeichner

CAS
156-87-6
PubChem CID
9086
DTXSID
DTXSID0059746
ChEMBL
CHEMBL115530
ChEBI
CHEBI:143408
UNII
YMA7C44XGY
EC Number
205-864-4
Nikkaji
J2.560G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,1
Polarare Oberfläche (TPSA)
46,3 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
2
Schwere Atome
5

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Amino Alcohols, Other
SpringerMaterials Properties15N nuclear magnetic resonance spectrum
Density · 3 Einträge

0.982 at 68 °F (USCG, 1999) - Less dense than water; will float

0.9824 @ 26 °C/4 °C

0.985 @25 °C

Color/FormCOLORLESS LIQUID
Solubility · 2 Einträge

SOL IN WATER, ALCOHOL & ETHER

MISCIBLE WITH ACETONE & CHLOROFORM

Flash Point · 2 Einträge

175 °F (USCG, 1999)

175 °F

Physikochemische Eigenschaften

Schmelzpunkt
10 · 10-12 °C (lit.)
Siedepunkt
184 · 184-187 °C (lit.)
Dichte
0.982 g/mL · 0.982 g/mL at 20 °C (lit.)
Dampfdichte
2.59 · 2.59 (vs air)
Dampfdruck
2.1 mm · 2.1 mm Hg ( 20 °C)
Brechungsindex
20 · n20/D 1.4598(lit.)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 0.4% (1 of 259) of reports.

Danger

H302 (92.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 259 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Gefahrenhinweise

Regulatory Information · 4 Einträge

Chemical: 1-Propanol, 3-amino-

1-Propanol, 3-amino- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Propanol, 3-amino- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 17-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13762

3-Amino-1-propanol: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelCorrosive
Fire HazardsSpecial Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.
Health HazardsIf inhaled may be harmful. Contact may cause burns to skin and eyes. (Organic base.) (USCG, 1999)
Hazards Summary · 1 Eintrag

A severe eye and moderate to severe skin irritant; [RTECS] Moderately toxic by ingestion; [CAMEO] A moderate irritant; [HSDB] A fairly severe skin irritant that may cause second-degree burns following a few minutes contact; Causes irritation or burns to eyes; Vapors cause moderate irritation; [CHRIS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Harmful by ingestion and skin absorption; [Alfa Aesar MSDS]

Reactive GroupAlcohols and Polyols

Sicherheit und Schutzausrüstung

Fire FightingFire Extinguishing Agents: Small fires: Dry chemical, CO2, water spray or alcohol foam. Large fires: Water spray, fog or alcohol foam. (USCG, 1999)
First AidINHALATION: Move victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Nonfire Spill ResponseNeutralizing Agents for Acids and Caustics: Cover spilled material with sodium bisulfate. Flush with water. (USCG, 1999)
Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Protective Action Criteria (PAC) · 3 Einträge

4.0 [mg/m3]

44 [mg/m3]

270 [mg/m3]

Personal Protective Equipment (PPE)Wear butyl rubber gloves and face shield or all-purpose canister respirator for spills. Wear self-contained breathing apparatus and full protective clothing for fires. (USCG, 1999)

Toxikologische Informationen

Adverse EffectsDermatotoxin - Skin burns.
Human Toxicity ExcerptsMODERATELY TOXIC BY INGESTION; MODERATE IRRITANT TO TISSUE.

Sicherheitsdaten

wgk
1
tsca
TSCA listed
ridadr
UN 2735 8/PG 2
hs_code
29221980
RTECS-Nr.
UA5600000
risk_code
22-34-20/21/22

Chemie und Industrie

Verwendung und Herstellung

Uses · 3 Einträge

Used as a chemical intermediate; [HSDB]

CHEM INT FOR DEXPANTHENOL, A GASTROINTESTINAL DRUG

Organic intermediate

U.S. Exports · 2 Einträge

(1977) No Data

(1979) No Data

U.S. Imports · 2 Einträge

(1977) No Data

(1979) No Data

U.S. Production · 3 Einträge

2023: 100,000 - <250,000 lb

(1977) No Data

(1980) PROBABLY GREATER THAN 2.27X10+6 GRAMS

Industry UsesOther
Formulations/PreparationsGRADE: 99% PURE.

Anwendungen

VerwendenOrganic intermediate.

Anbieter50 Anbieter

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