[(Naphthyloxy)methyl]oxiran

2-((1-Naphthalenyloxy)methyl)oxirane

HCID 91521

Notizen Reaktionen

Teilstruktursuche Ähnliche Strukturen suchen

Grundinformationen

CAS: 2461-42-9
Standard-SMILES: c1ccc2c(OCC3CO3)cccc2c1
InChIKey: QYYCPWLLBSSFBW-UHFFFAOYSA-N
Summenformel: C13H12O2
Durchschnittliche Molmasse: 200,23 g/mol
Monoisotopische Masse: 200,08372962

Überblick

induces hypoxanthine phosphoribosyl transferase mutants

Namen und Bezeichner

Bevorzugter Name: 2-((1-Naphthalenyloxy)methyl)oxirane
IUPAC: 2-(naphthalen-1-yloxymethyl)oxirane
Lokaler Name: [(Naphthyloxy)methyl]oxiran
Englischer Name: 2-[(1-Naphthyloxy)methyl]oxirane
Summenformel: C13H12O2
Molmasse: 200.23

Namen und Synonyme

2461-42-9Glycidyl 1-naphthyl etherNaphthalene, 1-(2,3-epoxypropoxy)-NSC-63207FN14F351DTXSID5010309862-[(1-Naphthalenyloxy)methyl]oxirane2-((1-Naphthalenyloxy)methyl)oxiraneRefChem:555893DTXCID20221699219-555-72-[(1-Naphthyloxy)methyl]oxirane

Weitere Namen anzeigen

Propranolol Epoxide impurityEPOXY IMPURITYUNII:07FN14F351Propranolol EpoxidePropranolol PEP2 StdNaftopidil Impurity 1Propanolol Impurity 6Propranolol Impurity 7

2-((Naphthalen-1-yloxy)methyl)oxiraneNaphthyl glycidyl ether1-Naphthyl glycidyl ether1-Naphthol Glycidyl Ether2-(naphthalen-1-yloxymethyl)oxirane3-(1-Naphthoxy)-1,2-epoxypropane2-(1-naphthyloxymethyl)oxiranealpha-naphthyl glycidyl ether

Datenbank-Bezeichner

CAS: 2461-42-9
PubChem CID: 91521
DTXSID: DTXSID501030986
ChEMBL: CHEMBL1929345
UNII: 07FN14F351
EC Number: 219-555-7
Nikkaji: J216.102H

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 3,3
Polarare Oberfläche (TPSA): 21,8 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 3
Schwere Atome: 15
Formalladung: 0
Komplexität: 217

Experimentelle und physikochemische Eigenschaften

PolymersPlastics & Rubber -> Glycidyl Ethers

Physikochemische Eigenschaften

Schmelzpunkt: 95 °C · 95 °C
Siedepunkt: 163 · 163-167
Dichte: 1.192 · 1.192±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
Löslichkeit: Chloroform (Slightly), Ethyl Acetate (Slightly)
Aggregatzustand: Oil
Farbe: Clear Light Yellow
CAS Datenbank: 2461 · 2461-42-9(CAS DataBase Reference)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 8 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 28-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/17936

Hazards SummaryAllergic contact dermatitis reported in resin handlers; [Kanerva, p. 1799]

Hazard Classes and CategoriesAcute Tox. 4 (50%)

Toxikologische Informationen

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

Sicherheitsdaten

hs_code: 2910900090

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

Used as a reactive diluent in epoxy resins; [Kanerva, p. 1799]

Plastic Composites Manufacturing [Category: Industry]

Anwendungen

BeschreibungGlycidyl ethers are used as reactive diluents for epoxy resins. Alpha-naphtyl glycidyl ether is formed by adding epichlorhydrin and sodium hydroxide to alpha-naphtol. Contact dermatitis was reported in workers of a chemical plant.

Verwenden2-[(1-Naphthyloxy)methyl]oxirane is used in the preparation of Naftopidil (N213500) and propranolol (P831800).