L-(-)-Xylose

L-Xylose

HCID 95259CAS 609-06-3

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Grundinformationen

Standard-SMILES: O=C[C@@H](O)[C@H](O)[C@@H](O)CO
InChIKey: PYMYPHUHKUWMLA-WISUUJSJSA-N
Summenformel: C5H10O5
Durchschnittliche Molmasse: 150,13 g/mol
Monoisotopische Masse: 150,05282342

Überblick

Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.

Namen und Bezeichner

Bevorzugter Name: L-Xylose
IUPAC: (2S,3R,4S)-2,3,4,5-tetrahydroxypentanal
Lokaler Name: L-(-)-Xylose
Englischer Name: L-xylose
Summenformel: C5H10O5
Molmasse: 150.13

Namen und Synonyme

L-xylose609-06-3(2S,3R,4S)-2,3,4,5-tetrahydroxypentanalL(+)-XyloseL-xylo-pentosealdehydo-L-xyloseXylose, L-A4JW0V2MYACHEBI:17979DTXSID50883340NSC-26213RefChem:151985

Weitere Namen anzeigen

XYLOSEXYLOSE, LL-Xylose,99%laevo-xyloseL-Xylose (9CI)

GlyTouCan:G41915IHCHEBI:65328DTXCID301022878G41915IH210-174-1L-(-)-XYLOSEMFCD00151096L-Xyl

Datenbank-Bezeichner

CAS: 609-06-3
PubChem CID: 95259
DTXSID: DTXSID50883340
ChEBI: CHEBI:17979
UNII: A4JW0V2MYA
EC Number: 210-174-1
Nikkaji: J82.126H

Eigenschaften

Berechnete Struktureigenschaften

XLogP: -2,3
Polarare Oberfläche (TPSA): 98 Å²
H-Brücken-Donoren: 4
H-Brücken-Akzeptoren: 5
Frei drehbare Bindungen: 4
Schwere Atome: 10
Formalladung: 0
Komplexität: 104

Physikochemische Eigenschaften

Schmelzpunkt: 150 · 150-152 °C(lit.)
Siedepunkt: 191.65 °C · 191.65°C (rough estimate)
Dichte: 1.525 · 1.525
Brechungsindex: -20 ° · -20 ° (C=10, H2O)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit: 2 O: · H2O: 0.1 g/mL, clear, colorless
Aggregatzustand: Crystalline Powder
pka: 12.46 · 12.46±0.20(Predicted)
Farbe: White to off-white
Wasserlöslichkeit: within almost transparency
BRN: 1723080 · 1723080
InChI: 1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5+/m1/s1
InChIKey: SRBFZHDQGSBBOR-VVZXFQNISA-N
SMILES: O[C@H]1COC(O)[C@@H](O)[C@@H]1O
LogP: -2.39 · -2.390 (est)
CAS Datenbank: 609 · 609-06-3(CAS DataBase Reference)
EPA chemische Informationen: L-Xylose (609-06-3)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 71.4% (5 of 7) of all reports.

Warning

H315 (28.6%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationL-Xylose: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (28.6%)

Sicherheitsdaten

F: 3-10
wgk: 3
tsca: TSCA listed
hs_code: 29400000
risk_code: 36/37/38
hazard_code: Xi
safety_code: 24/25-36-26
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationL-Xylose: ACTIVE

Anwendungen

VerwendenL-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Darstellung · 1 Eintrag

synthetischeL-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).