Grundinformationen
- CAS
334-50-9- Standard-SMILES
Cl.Cl.Cl.NCCCCNCCCN- InChIKey
LCNBIHVSOPXFMR-UHFFFAOYSA-N- Summenformel
- C7H22Cl3N3
- Durchschnittliche Molmasse
- 254,6 g/mol
- Monoisotopische Masse
- 253,087931
Überblick
Spermidine trihydrochloride is an organic molecular entity. It has a role as an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is functionally related to a spermidine.
Namen und Bezeichner
- Bevorzugter Name
- Spermidine trihydrochloride
- IUPAC
- N'-(3-aminopropyl)butane-1,4-diamine;trihydrochloride
- Lokaler Name
- 4-Azoniaoctamethylendiammoniumtrichlorid
- Englischer Name
- Spermidine trihydrochloride
- Summenformel
- C7H22Cl3N3
- Molmasse
- 254.63
Namen und Synonyme
Spermidine trihydrochloride334-50-9Spermidine hydrochlorideSpermidine HClN-(3-Aminopropyl)-1,4-butanediamine trihydrochlorideEINECS 206-379-0NSC 5283991,4-BUTANEDIAMINE, N-(3-AMINOPROPYL)-, TRIHYDROCHLORIDE1O14BED3981,4-Butanediamine, N-(3-aminopropyl), hydrochloride4-Azoniaoctamethylenediammonium trichlorideNSC-528399
Weitere Namen anzeigen
SPERMIDINE 3HCLN-(3-AMINOPROPYL)-1,4-DIAMINO-BUTANE TRIHYDROCHLORIDESpermidie 3HCLSPD·3HClSperMidine triSPERMIDINE 3HCSperpmidine HCLSpermidine 3HCl>98%
SPERMIDINE TRIHYDROCHLORIDE [MI]1,4-Butanediamine, N1-(3-aminopropyl)-, hydrochloride (1:3)RefChem:888501SPERMIDINE HCL [INCI]4Azoniaoctamethylenediammonium trichlorideN(3Aminopropyl)1,4butanediamine trihydrochloride1,4Butanediamine, N(3aminopropyl), hydrochloride1,4Butanediamine, N(3aminopropyl), trihydrochloride
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 64,1 Ų
- H-Brücken-Donoren
- 6
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 7
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 56,8
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Uses -> Biochemical Research
Physical DescriptionSolid; [Merck Index] White hygroscopic powder; [Sigma-Aldrich MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 257 · 257-259 °C(lit.)
- storage temp.
- room temp
- Löslichkeit
- 2 O: · H2O: 1 M at 20 °C, clear, colorless
- Aggregatzustand
- Crystalline Powder
- Farbe
- White
- PH
- 3 · 3.0-6.0 (25℃, 1M in H2O)
- Biologische Quelle
- microbialsynthetic
- Wasserlöslichkeit
- Soluble in water (100 mg/ml), and ethanol.
- BRN
- 3552356 · 3552356
- Kosmetik-Inhaltsstoffe Funktionen
- HAIR CONDITIONING
- InChI
- InChI=1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 48 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information1,4-Butanediamine, N-(3-aminopropyl)-, trihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards SummaryCauses convulsions in acute intraperitoneal studies of rats and mice; [RTECS] A skin and strong eye irritant; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- F
- 3-10
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29212900
- RTECS-Nr.
- EJ7023000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Verwendung und Herstellung
UsesFound widely in nature and essential for tissue growth; Used as a tool in biochemical research; [Merck Index]
General Manufacturing Information1,4-Butanediamine, N1-(3-aminopropyl)-, hydrochloride (1:3): ACTIVE
Anwendungen
BeschreibungSpermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins. Additionally, spermidine stimulates T4 polynucleotide kinase activity. It is involved in growth, development, and the stress response in plants.
VerwendenSpermidine Trihydrochloride is a NOS1 inhibitor and NMDA and T4 activator. Polyamine that plays an important role in the regulation of cellular proliferation and differentiation. It was in a structural and functional study of polyamines, where potassium and sodium ions were found to promote different effects when binding with polyamines. Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.
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山西玉宁生物科技有限公司13623677056 · [email protected]
山东科立康药业有限公司053-88113608 17854192669
山东天微医药科技有限公司+86-18653895227 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
济南诚汇双达生物有限公司053158897070 15550412551
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