2,4-Difluoranilin

2,4-Difluoroaniline

HCID 9709CAS 367-25-9

Grundinformationen

Standard-SMILES
Nc1ccc(F)cc1F
InChIKey
CEPCPXLLFXPZGW-UHFFFAOYSA-N
Summenformel
C6H5F2N
Durchschnittliche Molmasse
129,11 g/mol
Monoisotopische Masse
129,0390056

Überblick

2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
2,4-Difluoroaniline
IUPAC
2,4-difluoroaniline
Lokaler Name
2,4-Difluoranilin
Englischer Name
2,4-Difluoroaniline
Summenformel
C6H5F2N
Molmasse
129.11

Namen und Synonyme

2,4-DIFLUOROANILINE367-25-92,4-DifluorobenzenamineBenzenamine, 2,4-difluoro-Aniline, 2,4-difluoro-DTXSID602506440P93L7KWDNSC-10297DTXCID905064RefChem:82418206-687-52,4-Difluroaniline
Weitere Namen anzeigen
Difluoroaniline4-Difluoroaniline2,4-difluoro-anilinAKOS 911272,4-Difluoranilin2,4-DIFLOUROANILINE
2,4-DifluorophenylamineMFCD000076482.4-difluoroaniline2,?4-?difluoro-BenzenamineFlurbiprofen Impurity 53CCRIS 46212,4-Difluoro AnilineEINECS 206-687-5

Datenbank-Bezeichner

CAS
367-25-9
PubChem CID
9709
DTXSID
DTXSID6025064
ChEMBL
CHEMBL1423658
UNII
40P93L7KWD
EC Number
206-687-5
Nikkaji
J193.875D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
1,5
Polarare Oberfläche (TPSA)
26 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
0
Schwere Atome
9

Experimentelle und physikochemische Eigenschaften

Density1.268 (NTP, 1992) - Denser than water; will sink
Solubility10 to 50 mg/mL at 68.9 °F (NTP, 1992)
Flash Point145 °F (NTP, 1992)
Boiling Point338 °F at 753 mmHg (NTP, 1992)
Melting Point18.5 °F (NTP, 1992)
Physical Description2,4-difluoroaniline is a dark reddish-purple liquid. (NTP, 1992)

Physikochemische Eigenschaften

Schmelzpunkt
-7.5 °C · -7.5 °C (lit.)
Siedepunkt
170 °C/753 · 170 °C/753 mmHg (lit.)
Dichte
1.268 g/mL · 1.268 g/mL at 25 °C (lit.)
Brechungsindex
20 · n20/D 1.506(lit.)
Flammpunkt
145 °F · 145 °F
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H302 (99.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 157 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: Benzenamine, 2,4-difluoro-

Status: Active Update: 19-02-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24338

Benzenamine, 2,4-difluoro-: Does not have an individual approval but may be used under an appropriate group standard

DOT LabelPoison
Fire HazardsThis compound is combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: This compound may be irritating to tissues. (NTP, 1992)
Reactive GroupAryl Halides
Reactivity Profile · 1 Eintrag

Anilines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Sicherheit und Schutzausrüstung

Fire FightingFires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Sicherheitsdaten

F
8-9-23
wgk
1
tsca
TSCA listed
ridadr
UN 2941 6.1/PG 3
hs_code
29214210
RTECS-Nr.
BX3680000

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationBenzenamine, 2,4-difluoro-: ACTIVE

Anwendungen

Verwenden2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

Anbieter50 Anbieter

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