Milbemectin M.A3
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Grundinformationen
- CAS
51570-36-6- Standard-SMILES
CC1=C[C@H]2C(=O)O[C@H]3C[C@@H](C/C=C(\C)C[C@@H](C)/C=C/C=C4\CO[C@H]([C@@H]1O)[C@@]42O)O[C@@]1(CC[C@H](C)[C@@H](C)O1)C3- InChIKey
ZLBGSRMUSVULIE-GSMJGMFJSA-N- Summenformel
- C31H44O7
- Durchschnittliche Molmasse
- 528,686 g/mol
- Monoisotopische Masse
- 528,30870375
Namen und Bezeichner
- Bevorzugter Name
- Milbemectin M.A3
- IUPAC
- [2'R,2a(3)E,4E,5'S,6R,6'R,8E,11R,15S,17aR,20R,20aR,20bS]-20,20b-Dihydroxy-5',6,6',8,19-pentamethyl-6,7,10,11,14,15,17a,20,20a,20b-decahydro-2H,17H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-oxan]-17-one
- Englischer Name
- MILBEMECTIN A3
- Summenformel
- C31H44O7
- Molmasse
- 528.69
Namen und Synonyme
milbemycinmilbemycin A3Milbemycin α1milbemycinb-2MILBEMECTIN A3milbemectine a3Antibiotic B-41A3Milbemycin oxime A3Milbemycin EP Imp BMilbemite Impurity 1
Datenbank-Bezeichner
- CAS
51570-36-6、51596-10-2- PubChem CID
- 9828343
- DTXSID
DTXSID1058391- ChEMBL
CHEMBL2272396、CHEMBL499030- ChEBI
CHEBI:39228- UNII
- C76Y8Z9GEX
- EC Number
- 610-705-0、684-598-4
- Nikkaji
- J34.159B
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 212 · 212-215°; mp 192-194°
- Siedepunkt
- 725.5 · 725.5±60.0 °C(Predicted)
- Dichte
- 1.21 · 1.21±0.1 g/cm3(Predicted)
- storage temp.
- 0 · 0-6°C
- Löslichkeit
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- Aggregatzustand
- A solid
- pka
- 12.46 · 12.46±0.70(Predicted)
- Farbe
- White to light yellow
- Henry's Law Constant
- 6.5 · 6.5×102 mol/(m3Pa) at 25℃, Maniere et al. (2011)
- InChIKey
- ZLBGSRMUSVULIE-HIKHPYAJNA-N
- EPA chemische Informationen
- 3 · Milbemycin A3 (51596-10-2)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- ridadr
- 2588
- hazard_class
- 6.1(b)
- packing_group
- III
Chemie und Industrie
Anwendungen
BeschreibungMilbemycin A3 is a member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin A3 is used as a nematocide and insecticide. The acaricidal and nematocidal activity of a mixture of milbemycin A3 and milbemycin A4 against adult spider mites, spider mite eggs, and C. elegans are reported at IC50 values of 5.3, 41.1, and 9.5 μg/ml.
VerwendenMilbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A3 is a major member of a group of analogues containing a 25-methyl substituent. Milbemycin A3 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.
Anbieter47 Anbieter
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
深圳市简一生物科技有限公司0755-84826604 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
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